Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   D9C20_RS09505 Genome accession   NZ_CP032867
Coordinates   1784469..1785671 (-) Length   400 a.a.
NCBI ID   WP_014481472.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis strain N4-2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1779469..1790671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D9C20_RS09470 (D9C20_09470) - 1779947..1780900 (-) 954 WP_014481469.1 sporulation-delaying protein SdpB family protein -
  D9C20_RS09475 (D9C20_09475) - 1780885..1781439 (-) 555 WP_015715050.1 SdpA family antimicrobial peptide system protein -
  D9C20_RS09480 (D9C20_09480) - 1781623..1782258 (-) 636 WP_014481470.1 SdpI family protein -
  D9C20_RS09485 (D9C20_09485) - 1782258..1782542 (-) 285 WP_015715052.1 autorepressor SdpR family transcription factor -
  D9C20_RS09490 (D9C20_09490) rocR 1782769..1784154 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  D9C20_RS09495 (D9C20_09495) - 1784136..1784288 (-) 153 Protein_1862 ATP-binding protein -
  D9C20_RS09500 (D9C20_09500) - 1784316..1784448 (-) 133 Protein_1863 hypothetical protein -
  D9C20_RS09505 (D9C20_09505) htrA 1784469..1785671 (-) 1203 WP_014481472.1 serine protease HtrC Regulator
  D9C20_RS09510 (D9C20_09510) vicX 1785753..1786547 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  D9C20_RS09515 (D9C20_09515) walI 1786569..1787411 (-) 843 WP_014481473.1 WalRK two-component regulatory system regulator WalI -
  D9C20_RS09520 (D9C20_09520) walH 1787398..1788765 (-) 1368 WP_014481474.1 WalRK two-component regulatory system regulator WalH -
  D9C20_RS09525 (D9C20_09525) walK 1788755..1790590 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42761.51 Da        Isoelectric Point: 5.1904

>NTDB_id=280071 D9C20_RS09505 WP_014481472.1 1784469..1785671(-) (htrA) [Bacillus subtilis subsp. subtilis strain N4-2]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGVVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=280071 D9C20_RS09505 WP_014481472.1 1784469..1785671(-) (htrA) [Bacillus subtilis subsp. subtilis strain N4-2]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGTTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAATGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGTGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCAGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(231-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.264

96.5

0.417
  htrA Streptococcus pneumoniae TIGR4

45.455

82.5

0.375
  htrA Streptococcus pneumoniae D39

45.455

82.5

0.375
  htrA Streptococcus pneumoniae Rx1

45.455

82.5

0.375
  htrA Streptococcus pneumoniae R6

45.455

82.5

0.375