Detailed information NTG0276989

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: CFN54_RS00470
• Genome accession: NZ_CP032635
• Coordinates: 98024..99283 (+)
• Length: 419 a.a.
• NCBI ID: WP_025016471.1
• Uniprot ID: -
• Organism: Latilactobacillus sakei strain ZFM225
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 93024..104283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CFN54_RS00455 (CFN54_00455)	-	94892..96223 (+)	1332	WP_035147594.1	YycH family regulatory protein	-
CFN54_RS00460 (CFN54_00460)	-	96228..97049 (+)	822	WP_035147596.1	two-component system regulatory protein YycI	-
CFN54_RS00465 (CFN54_00465)	vicX	97084..97890 (+)	807	WP_016264363.1	MBL fold metallo-hydrolase	Regulator
CFN54_RS00470 (CFN54_00470)	htrA	98024..99283 (+)	1260	WP_025016471.1	S1C family serine protease	Regulator
CFN54_RS00475 (CFN54_00475)	rlmH	99828..100307 (+)	480	WP_011373797.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
CFN54_RS00480 (CFN54_00480)	-	100447..101106 (+)	660	WP_025016470.1	hypothetical protein	-
CFN54_RS00485 (CFN54_00485)	add	101163..102188 (-)	1026	WP_035147601.1	adenosine deaminase	-
CFN54_RS00490 (CFN54_00490)	-	102358..103701 (+)	1344	WP_151388575.1	NCS2 family permease	-

Sequence

Protein

• Length: 419 a.a.
• Molecular weight: 42698.80 Da
• Isoelectric Point: 9.4566

>NTDB_id=276989 CFN54_RS00470 WP_025016471.1 98024..99283(+) (htrA) [Latilactobacillus sakei strain ZFM225]
MNQNSGLMKTAVVAVISALIGGGAAYAGFSRLGSSANDVTTATQTPTKAGATKISNIKVNSSSQTTTAFQKVNTSVVSVV
NLQKQQQSTGDLSSLFGSGSTNSNSSSSKSSSSDLEESSEGSGLIYEKKDGKAYIVTNNHVVAGSDKIEVILSDGTKLEA
SLVGTDAVSDLAVLKINGTKVKKTATFGDSDSIKAGESVLAIGSPLGSEYATSVTQGIISAKKRTIDVTDETTGQTTGQA
TVIQTDTAINPGNSGGPLVNMAGQVVGINSMKLASNGDTTVEGMGFAIPSNEVVKIINQLVANGKVVRPALGISVIDLTN
ISSTQQSSVLKLPSTVNSGVVVASVTSNSVAKKAGISKYDVIVGLGGKTVSSVADLHTILYSYAMNSTTEIQYYHNGSLK
KANVKLTQAASSDSTTTTK

Nucleotide

• Length: 1260 bp

>NTDB_id=276989 CFN54_RS00470 WP_025016471.1 98024..99283(+) (htrA) [Latilactobacillus sakei strain ZFM225]
ATGAATCAAAATTCAGGATTAATGAAAACAGCGGTTGTTGCAGTTATTTCAGCATTGATTGGTGGGGGCGCAGCCTATGC
CGGTTTTTCTCGACTCGGCAGTTCGGCCAATGATGTCACGACTGCAACGCAGACGCCTACTAAAGCGGGGGCAACTAAGA
TTAGTAATATCAAAGTGAACTCATCATCACAGACGACAACAGCCTTCCAAAAGGTTAATACATCAGTTGTATCCGTTGTG
AACTTACAAAAACAACAACAATCAACCGGTGACCTGAGTTCATTATTTGGTTCAGGCAGCACCAACAGCAATAGTAGTTC
TTCTAAGAGCAGTAGCAGTGATTTAGAAGAATCCAGTGAAGGTTCAGGTTTAATCTACGAGAAAAAAGACGGCAAAGCTT
ACATCGTGACGAATAATCACGTGGTTGCTGGTTCTGATAAAATCGAAGTCATTTTGAGTGATGGCACAAAATTGGAAGCT
AGTTTAGTTGGGACAGATGCTGTTTCTGATTTGGCTGTCTTAAAAATTAACGGGACTAAAGTGAAGAAGACGGCAACGTT
TGGTGATTCAGATAGTATCAAAGCTGGTGAATCAGTTCTTGCGATCGGCTCACCATTGGGTTCAGAATACGCAACTTCTG
TCACACAAGGGATCATTTCTGCTAAGAAACGGACAATTGATGTGACGGACGAAACAACTGGCCAAACAACTGGTCAAGCG
ACTGTTATTCAAACTGATACAGCGATTAACCCTGGGAACTCAGGTGGCCCATTAGTTAATATGGCCGGTCAAGTTGTTGG
GATTAATTCAATGAAGTTAGCCTCAAATGGTGATACGACAGTTGAAGGGATGGGCTTTGCTATTCCAAGTAACGAAGTTG
TTAAAATTATTAATCAATTAGTGGCTAACGGGAAAGTCGTTAGACCAGCACTTGGGATTAGTGTGATAGATTTAACCAAT
ATTTCATCAACACAACAATCTTCAGTATTAAAACTACCATCAACCGTCAATAGCGGGGTAGTGGTTGCCTCAGTAACAAG
CAATTCAGTTGCTAAGAAAGCTGGGATTAGTAAATACGATGTGATTGTCGGTTTAGGCGGCAAGACGGTTTCAAGCGTTG
CAGACTTACACACAATCCTATACAGTTACGCGATGAATAGTACAACTGAAATTCAGTACTACCATAATGGCAGCTTGAAA
AAAGCGAATGTTAAACTTACACAAGCAGCTTCATCAGATAGTACGACAACAACTAAATAA

Domains

Predicted by InterProScan.

• Peptidase family M50 (Peptidase_M50) (284-413)

• PDZ domain (PDZ_2) (309-406)

• Trypsin-like peptidase domain (Trypsin_2) (121-268)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	45.209	97.136	0.439
htrA	Streptococcus gordonii str. Challis substr. CH1	42.512	98.807	0.42
htrA	Streptococcus mutans UA159	45.968	88.783	0.408
htrA	Streptococcus pneumoniae TIGR4	48.424	83.294	0.403
htrA	Streptococcus pneumoniae R6	48.424	83.294	0.403
htrA	Streptococcus pneumoniae Rx1	48.424	83.294	0.403
htrA	Streptococcus pneumoniae D39	48.424	83.294	0.403