Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SSA_RS09585 Genome accession   NC_009009
Coordinates   1954751..1955503 (-) Length   250 a.a.
NCBI ID   WP_011837465.1    Uniprot ID   A3CQ78
Organism   Streptococcus sanguinis SK36     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1949751..1960503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS09565 (SSA_1954) - 1950156..1951388 (-) 1233 WP_002917693.1 cysteine desulfurase -
  SSA_RS09570 (SSA_1955) sufD 1951430..1952692 (-) 1263 WP_004185458.1 Fe-S cluster assembly protein SufD -
  SSA_RS09575 (SSA_1956) sufC 1952734..1953504 (-) 771 WP_011837463.1 Fe-S cluster assembly ATPase SufC -
  SSA_RS09580 (SSA_1957) - 1953594..1954760 (-) 1167 WP_011837464.1 glycosyltransferase family 4 protein -
  SSA_RS09585 (SSA_1958) mecA 1954751..1955503 (-) 753 WP_011837465.1 adaptor protein MecA Regulator
  SSA_RS09590 (SSA_1959) - 1955679..1956521 (-) 843 WP_011837466.1 undecaprenyl-diphosphate phosphatase -
  SSA_RS09595 (SSA_1960) - 1956661..1958556 (-) 1896 WP_011837467.1 DUF2207 domain-containing protein -
  SSA_RS09600 (SSA_1961) - 1958688..1960253 (+) 1566 WP_011837468.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28852.56 Da        Isoelectric Point: 4.0662

>NTDB_id=27546 SSA_RS09585 WP_011837465.1 1954751..1955503(-) (mecA) [Streptococcus sanguinis SK36]
MEMKQISDSTIKITIQLEDLEKRGMEMADFLVPQEKTEEFFYTILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKL
DKNLSFEDLADLPDMDELSHMSPDEFLKTLEKSIFEKSKEDIEAVKSLETAEAEEREQLSQEAADEQSAENAERYIYYIL
RFEDIKAAAAFAQTVDYKIDLSELYKYDSAYYLTILVDVEGFPERYPAWLLAKMREFADDSDITRAVLQEHGHLLLVTDA
VSGLQKVECL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=27546 SSA_RS09585 WP_011837465.1 1954751..1955503(-) (mecA) [Streptococcus sanguinis SK36]
ATGGAAATGAAACAGATTAGTGATTCGACCATAAAAATCACGATTCAGCTGGAAGATTTGGAAAAGCGCGGCATGGAAAT
GGCCGATTTCTTGGTCCCCCAAGAAAAGACGGAAGAATTTTTCTATACCATCTTAGATGAGTTGGAAATGCCGGATAATT
TTTTGGACAGCGGTATGCTGAGCTTCCGTGTGACGCCTAAGCCAGATAAGGTGGATGTTTTTGTTACCAAGTCTAAGTTG
GATAAGAATCTGAGTTTTGAGGATTTGGCAGATTTGCCAGACATGGACGAGCTGTCTCATATGTCTCCAGATGAATTCCT
CAAGACACTGGAAAAGAGCATTTTTGAAAAGAGCAAGGAAGATATAGAAGCAGTCAAATCTTTGGAAACAGCCGAAGCAG
AGGAAAGAGAGCAGCTTTCTCAGGAGGCGGCGGATGAGCAGTCGGCAGAAAATGCAGAGCGCTATATATACTATATCCTG
CGCTTTGAAGATATTAAGGCTGCTGCGGCCTTTGCTCAGACGGTGGACTATAAGATTGACTTATCAGAACTTTATAAGTA
TGATTCAGCTTATTATTTGACGATTTTAGTAGATGTTGAGGGCTTCCCAGAACGCTATCCAGCTTGGCTCTTGGCTAAGA
TGCGTGAATTCGCAGATGATTCAGATATCACTCGGGCAGTGCTGCAGGAGCACGGACATCTGCTTTTGGTGACAGATGCC
GTCTCCGGCTTGCAGAAGGTTGAATGCCTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3CQ78

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.421

98.8

0.676
  mecA Streptococcus pneumoniae D39

68.421

98.8

0.676
  mecA Streptococcus pneumoniae R6

68.421

98.8

0.676
  mecA Streptococcus pneumoniae TIGR4

68.016

98.8

0.672
  mecA Streptococcus mutans UA159

49.393

98.8

0.488
  mecA Streptococcus thermophilus LMD-9

48.594

99.6

0.484
  mecA Streptococcus thermophilus LMG 18311

48.193

99.6

0.48

Multiple sequence alignment