Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SSA_RS09040 Genome accession   NC_009009
Coordinates   1838418..1840271 (-) Length   617 a.a.
NCBI ID   WP_011837403.1    Uniprot ID   A3CPX1
Organism   Streptococcus sanguinis SK36     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1833418..1845271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS09015 (SSA_1840) - 1834150..1834512 (-) 363 WP_002901252.1 S1 RNA-binding domain-containing protein -
  SSA_RS09020 (SSA_1841) - 1834512..1835912 (-) 1401 WP_011837402.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SSA_RS09025 (SSA_1842) - 1835952..1836584 (-) 633 WP_002893493.1 response regulator transcription factor -
  SSA_RS09030 (SSA_1843) - 1836562..1837581 (-) 1020 WP_002893495.1 sensor histidine kinase -
  SSA_RS09035 (SSA_1844) liaF 1837578..1838273 (-) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  SSA_RS09040 (SSA_1845) stkP 1838418..1840271 (-) 1854 WP_011837403.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SSA_RS09045 (SSA_1846) - 1840268..1841008 (-) 741 WP_002896965.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SSA_RS09050 (SSA_1847) rsmB 1841027..1842343 (-) 1317 WP_002896964.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SSA_RS09055 (SSA_1848) fmt 1842333..1843268 (-) 936 WP_011837405.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 67340.19 Da        Isoelectric Point: 6.4426

>NTDB_id=27536 SSA_RS09040 WP_011837403.1 1838418..1840271(-) (stkP) [Streptococcus sanguinis SK36]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENSPISNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIISENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYERRNEKKLVFDDVAKADTKTLPKISPVPQPAVPPVKPTPPKAEAT
EVKEETADAVKKVPKKRRLRTRYKVLFFAVLLVLAAFVVLLYNSPSNTSVPDVSGQTVAEARSAIEAKKLVVGDEKEEYS
DNVESGKVIKTDPQANSQRREGSKIDLIISKGPKTFVMEDYVGQAKSAAVENLKTNYNVSEKLIEIVEEESDEYEPGQVI
RQSPAAGSTYDLTSNHKIKLTVAKEVTSVSMPDFGSMQYTYANARSYLIQMGISSSRIERVVDRSVTSTQADLVTSQSPA
AGQTIDLKSNEKITLYVTEATTPSSSSSSSSSSSSSSKSSSSSEDSGHGTSSSSSDS

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=27536 SSA_RS09040 WP_011837403.1 1838418..1840271(-) (stkP) [Streptococcus sanguinis SK36]
ATGATTCAAATCGGCAAAATCTTTGCCGGGCGATATAAAATTATCAAGCAGATTGGCCGCGGAGGTATGGCAGATGTCTA
TCTGGCCAAAGACTTGATTTTGGATGGTGAGGAAGTTGCGGTAAAGGTTCTTAGGACCAATTACCAGACAGATCCTATCG
CTGTCGCGCGTTTCCAGCGGGAAGCTAAGGCGATGGCTGACTTGGACCATCCGCACATCGTTCGGATTACTGATATTGGG
GAAGAAGATGGCCAGCAGTATCTGGCTATGGAATACGTGGCAGGTCTTGACCTCAAGCGCTATATCAAAGAGAATTCTCC
GATTTCAAATGAAGAAGCAGTCAGAATCATGGGACAAATCTTGCTGGCGATGCGCTTGGCGCATACACGCGGTATTGTCC
ATCGTGACCTGAAACCACAAAATGTCCTCTTGACCCCAGATGGCAATGCCAAGGTAACAGACTTTGGAATTGCGGTGGCC
TTTGCGGAGACAAGTCTGACTCAGACTAACTCAATGCTAGGCTCAGTTCATTATCTATCGCCTGAGCAGGCACGTGGCTC
TAAAGCAACTGTTCAGAGTGATATTTATGCGATGGGGATTATTTTTTATGAGATGCTGACTGGTCATATCCCTTATGATG
GGGATAGTGCCGTTACGATTGCTCTTCAGCATTTCCAAAAGCCGCTGCCATCCATCATTTCTGAAAATCCTAATGTGCCT
CAGGCATTGGAAAATGTTGTCATTAAGGCAACAGCCAAAAAACTGACGGATCGTTATCAGTCAGTTGCAGAGATGTATGT
TGACTTGTCCAGTAGCTTATCTTATGAGCGCCGCAATGAAAAGAAATTAGTCTTTGATGATGTTGCGAAAGCAGACACCA
AGACCTTGCCAAAAATCTCACCTGTACCGCAGCCAGCAGTTCCACCTGTTAAGCCAACTCCGCCTAAAGCGGAAGCGACT
GAAGTTAAGGAAGAGACAGCTGATGCGGTTAAGAAAGTTCCAAAGAAACGTCGCTTGAGAACGCGTTATAAAGTACTTTT
CTTTGCAGTCCTATTGGTTTTGGCGGCTTTTGTTGTCCTTCTTTATAATAGCCCATCCAATACCAGCGTACCAGATGTTT
CTGGCCAGACTGTAGCAGAGGCTCGCTCCGCTATTGAAGCTAAGAAGCTGGTTGTCGGAGACGAAAAGGAAGAATACAGC
GACAATGTCGAATCTGGCAAAGTCATTAAAACCGATCCACAGGCCAACAGTCAGCGCCGCGAAGGCAGCAAGATTGACCT
GATTATCTCCAAGGGCCCCAAGACCTTTGTAATGGAAGATTATGTTGGACAAGCAAAATCAGCCGCAGTTGAAAATCTGA
AAACAAACTATAATGTTTCTGAGAAATTGATTGAGATTGTTGAGGAAGAATCGGACGAGTACGAGCCAGGTCAGGTGATT
CGTCAGTCTCCGGCAGCTGGTTCGACCTATGATTTGACTTCTAATCATAAGATTAAGCTGACAGTGGCCAAAGAAGTGAC
TAGTGTGTCCATGCCTGACTTTGGCAGCATGCAGTACACCTACGCTAATGCACGGTCTTACTTGATCCAAATGGGAATTT
CTTCTTCCCGAATTGAGCGAGTTGTTGACCGCTCAGTCACTTCGACTCAGGCAGACTTGGTAACTTCCCAGTCACCAGCA
GCAGGTCAGACAATCGATCTCAAGTCTAATGAAAAAATCACTCTTTACGTGACAGAAGCAACAACACCATCGTCATCTAG
TTCGTCATCATCATCGTCTAGCAGTAGCTCAAAGAGCAGCTCATCGTCTGAAGATAGTGGACATGGAACAAGTTCTAGCT
CATCTGATAGTTGA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(437-504)

PASTA domain (PASTA)

(510-578)

PASTA domain (PASTA)

(370-431)

Protein kinase domain (Pkinase)

(12-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3CPX1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.079

97.893

0.617
  stkP Streptococcus pneumoniae D39

62.748

97.893

0.614
  stkP Streptococcus pneumoniae R6

62.748

97.893

0.614
  stkP Streptococcus pneumoniae Rx1

62.583

97.893

0.613
  pknB Streptococcus mutans UA159

58.262

95.138

0.554
  stkP/pknB Streptococcus salivarius strain HSISS4

55.966

96.434

0.54

Multiple sequence alignment