Detailed information NTG0027517

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SSA_RS03760
• Genome accession: NC_009009
• Coordinates: 730808..731758 (+)
• Length: 316 a.a.
• NCBI ID: WP_011836698.1
• Uniprot ID: A3CLX7
• Organism: Streptococcus sanguinis SK36
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 725808..736758

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSA_RS03735 (SSA_0744)	queA	725866..726894 (-)	1029	WP_011836693.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
SSA_RS03740 (SSA_0745)	-	726904..727083 (-)	180	WP_002897949.1	hypothetical protein	-
SSA_RS03745 (SSA_0746)	nagB	727218..727925 (+)	708	WP_011836695.1	glucosamine-6-phosphate deaminase	-
SSA_RS03750 (SSA_0747)	-	728076..729431 (+)	1356	WP_011836696.1	DUF1958 domain-containing protein	-
SSA_RS03755 (SSA_0748)	-	729526..730695 (+)	1170	WP_011836697.1	MFS transporter	-
SSA_RS03760 (SSA_0749)	coiA	730808..731758 (+)	951	WP_011836698.1	competence protein CoiA	Machinery gene
SSA_RS03765 (SSA_0750)	-	731929..732315 (+)	387	WP_011836699.1	DUF1310 family protein	-
SSA_RS03770 (SSA_0751)	pepF	732507..734309 (+)	1803	WP_011836700.1	oligoendopeptidase F	Regulator
SSA_RS03775 (SSA_0752)	-	734311..734994 (+)	684	WP_011836701.1	O-methyltransferase	-
SSA_RS03780 (SSA_0753)	prsA	735108..736115 (+)	1008	WP_011836702.1	peptidylprolyl isomerase PrsA	-

Sequence

Protein

• Length: 316 a.a.
• Molecular weight: 37462.09 Da
• Isoelectric Point: 7.6554

>NTDB_id=27517 SSA_RS03760 WP_011836698.1 730808..731758(+) (coiA) [Streptococcus sanguinis SK36]
MFVARNHKGLLCNALEEKIEKGADFVCPACSGAVRFKKGKVMQPHFAHVSLEQCSFYRENESAEHLNLKAELFRWAVQTE
EVEVEAFLPALQQIADLLVDEKLALEVQCSLLSIERLQERTLSYRQHGYQVLWLLGRKLWLKDSLTRLQKDFLYFSKNMG
FHLWELDQEKQVLRLKYLIHEDLHGKVQHKTKNFPFGHGQLLDILRLPFQKQEMNSFLAQQDPQICSYIRRQLYYQQPRW
MRLQAQLYQAGDNLLTKAAEDFYPQVRPIQATSFCQITTDLTDYYQQFENYYANLQQKNLQIVYSPAFYEMIREKC

Nucleotide

• Length: 951 bp

>NTDB_id=27517 SSA_RS03760 WP_011836698.1 730808..731758(+) (coiA) [Streptococcus sanguinis SK36]
ATGTTTGTGGCGCGAAATCATAAGGGACTTTTGTGTAATGCTCTGGAGGAGAAGATTGAGAAGGGGGCTGATTTTGTCTG
CCCAGCTTGTTCGGGGGCAGTCCGTTTTAAAAAAGGAAAGGTCATGCAGCCGCATTTTGCGCATGTTTCGCTAGAGCAGT
GTAGCTTTTATAGGGAAAATGAGAGCGCTGAGCACCTCAATCTTAAGGCGGAGCTTTTTCGCTGGGCTGTCCAAACAGAA
GAAGTTGAGGTGGAGGCTTTTTTGCCTGCTCTGCAGCAGATTGCTGATCTACTGGTTGATGAAAAACTGGCGCTTGAAGT
CCAGTGCAGTCTCCTAAGTATAGAACGGTTGCAGGAACGGACGCTTTCTTACCGCCAGCATGGTTATCAGGTTCTCTGGC
TTTTGGGGCGAAAACTTTGGCTCAAGGATTCCCTAACTCGCCTGCAGAAGGATTTTCTCTATTTTAGTAAAAATATGGGC
TTTCATCTTTGGGAGCTAGATCAAGAAAAGCAAGTTCTGCGTCTCAAATACCTGATTCACGAAGATCTGCATGGAAAAGT
TCAGCACAAGACTAAGAACTTTCCCTTTGGTCACGGTCAGCTTTTGGATATTTTGCGTTTGCCCTTTCAAAAGCAGGAGA
TGAACAGCTTTCTTGCCCAGCAAGATCCGCAGATCTGCAGCTATATCCGCCGTCAGCTTTATTACCAGCAACCTAGATGG
ATGAGGCTGCAGGCTCAGCTCTATCAGGCTGGAGATAATCTCCTGACTAAGGCTGCAGAGGATTTTTATCCGCAGGTTCG
GCCAATACAAGCTACCTCCTTCTGTCAGATAACTACTGACCTGACTGACTATTACCAGCAGTTTGAGAATTATTACGCCA
ATCTCCAGCAAAAAAATCTGCAAATTGTTTATTCACCGGCTTTTTATGAGATGATAAGAGAAAAATGCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-265)

3D structure

• AlphaFold DB: A3CLX7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	55.484	98.101	0.544
coiA	Streptococcus pneumoniae TIGR4	53.871	98.101	0.528
coiA	Streptococcus pneumoniae Rx1	53.871	98.101	0.528
coiA	Streptococcus pneumoniae D39	53.871	98.101	0.528
coiA	Streptococcus pneumoniae R6	53.871	98.101	0.528
coiA	Lactococcus lactis subsp. cremoris KW2	42.769	100	0.44