Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   D2E16_RS01320 Genome accession   NZ_CP032064
Coordinates   255404..256765 (-) Length   453 a.a.
NCBI ID   WP_024376266.1    Uniprot ID   -
Organism   Streptococcus suis strain YSJ17     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 250404..261765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS12455 - 251109..251507 (-) 399 WP_029180393.1 hypothetical protein -
  D2E16_RS01290 (D2E16_01335) - 251733..251960 (+) 228 WP_024376261.1 hypothetical protein -
  D2E16_RS01295 (D2E16_01340) - 251941..252246 (+) 306 WP_044672279.1 hypothetical protein -
  D2E16_RS01300 (D2E16_01345) - 252537..252878 (+) 342 WP_024378069.1 LytTR family DNA-binding domain-containing protein -
  D2E16_RS01305 (D2E16_01350) comE/blpR 252878..253618 (+) 741 WP_024376264.1 response regulator transcription factor Regulator
  D2E16_RS01310 (D2E16_01355) - 253628..254959 (+) 1332 WP_192369168.1 GHKL domain-containing protein -
  D2E16_RS01315 (D2E16_01360) - 255157..255306 (-) 150 WP_079267743.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  D2E16_RS01320 (D2E16_01365) comB 255404..256765 (-) 1362 WP_024376266.1 bacteriocin secretion accessory protein Regulator
  D2E16_RS01325 (D2E16_01370) comA/nlmT 256775..258928 (-) 2154 WP_024376267.1 peptide cleavage/export ABC transporter Regulator
  D2E16_RS01330 (D2E16_01375) - 259233..259463 (+) 231 WP_024376268.1 bacteriocin class II family protein -
  D2E16_RS01335 (D2E16_01380) - 259465..259656 (+) 192 WP_024376269.1 hypothetical protein -
  D2E16_RS01340 - 260159..260299 (+) 141 WP_153308671.1 hypothetical protein -
  D2E16_RS01345 - 260319..260459 (+) 141 WP_153308672.1 hypothetical protein -
  D2E16_RS01350 (D2E16_01385) - 260474..261085 (+) 612 WP_024378066.1 CPBP family intramembrane glutamic endopeptidase -
  D2E16_RS01355 (D2E16_01390) - 261247..261543 (+) 297 WP_024376271.1 bacteriocin immunity protein -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 49595.86 Da        Isoelectric Point: 4.9973

>NTDB_id=274157 D2E16_RS01320 WP_024376266.1 255404..256765(-) (comB) [Streptococcus suis strain YSJ17]
MNTNLFRSAEFYQRRYHNFATLLILPLVLLVSFLFLFSFLAKKEVTVTSRGEITPTKVIASIQSTSNNPILANHLVANQA
VKKGDALIQYAETMEASQKQALESQVHNLEEQKKGLETLRNSLEQGTNLFTGEDNFGYGATFQQFVSQTQDLELGIAKTN
AEVTNQAALANHTAAAIDQQLSQLQQDIIAYEELKTAISTQASSLPTGNPHQATLNNYLAQVQGTPNPALSDQYISQINQ
TIAGLENSMASLSIQRAGTGSIATYDTSLATKIESLRAQFLQNAAQQLTTVESQLLQAKSQLDQAATQLEQTTITAPENG
VIALNPEFEGKNLIPVGSDIAYLYPDIKQTKTVLITYYVTSEYVALLKEGQTARLSLEKIGNQPIIVIGSIQSIAQSATP
TEEGNLFKITAQATITENESSLLQYGLQGRVTSVIAKKTFFDYYKDKLLHTNN

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=274157 D2E16_RS01320 WP_024376266.1 255404..256765(-) (comB) [Streptococcus suis strain YSJ17]
ATGAATACAAACCTATTTCGAAGTGCTGAATTTTATCAGCGACGCTACCATAATTTTGCGACCCTTTTGATTCTCCCCTT
GGTACTACTGGTCTCCTTCCTTTTTCTCTTCTCCTTCCTAGCTAAAAAAGAAGTCACTGTCACTTCACGAGGAGAGATTA
CTCCTACCAAGGTCATCGCCTCCATTCAATCAACCAGTAACAATCCTATTCTTGCCAATCATCTCGTAGCCAATCAAGCC
GTAAAAAAAGGCGATGCTCTCATCCAGTACGCCGAAACAATGGAGGCTTCCCAGAAGCAAGCCTTAGAAAGTCAAGTTCA
TAACCTAGAAGAGCAGAAAAAAGGGTTGGAGACCTTACGAAACAGTCTTGAACAGGGTACCAACCTCTTTACAGGAGAAG
ATAACTTTGGCTACGGAGCAACCTTTCAGCAATTCGTCAGCCAAACACAAGACCTAGAATTAGGTATCGCTAAAACGAAT
GCCGAGGTCACTAATCAAGCAGCTTTGGCCAATCACACCGCTGCTGCTATTGACCAACAACTCAGTCAACTCCAGCAGGA
CATCATCGCCTACGAGGAGCTTAAAACAGCGATTAGCACCCAAGCAAGTAGCTTGCCGACAGGCAATCCCCACCAGGCCA
CTCTGAACAACTACCTAGCCCAAGTCCAAGGAACACCAAATCCTGCCCTTAGTGATCAATACATCAGCCAGATTAACCAA
ACCATCGCAGGATTGGAAAACTCAATGGCTAGCCTCTCTATTCAACGGGCAGGTACTGGTAGCATCGCCACCTACGACAC
AAGTCTAGCGACTAAAATCGAAAGTTTACGTGCCCAGTTTCTACAAAACGCAGCTCAGCAACTGACCACTGTCGAATCTC
AATTGCTTCAGGCAAAGTCGCAACTCGATCAAGCAGCTACTCAATTAGAACAAACTACCATTACCGCTCCAGAAAATGGT
GTCATCGCCCTAAATCCTGAGTTCGAGGGAAAAAACTTGATTCCAGTAGGGAGCGATATCGCCTATCTCTATCCTGATAT
CAAGCAAACCAAGACCGTCCTTATCACCTACTATGTGACTTCGGAGTATGTCGCCCTCCTCAAAGAAGGCCAGACCGCCC
GACTAAGCTTAGAGAAAATCGGCAATCAGCCAATCATAGTCATCGGCTCCATCCAGTCTATCGCTCAATCCGCAACACCG
ACAGAAGAGGGCAATCTCTTTAAGATTACAGCCCAAGCTACCATTACAGAAAATGAAAGCTCACTTCTACAGTATGGTCT
ACAGGGTCGCGTCACCAGTGTGATTGCTAAGAAGACCTTCTTCGACTACTACAAAGATAAACTGCTTCACACAAATAATT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(313-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

38

99.338

0.377
  comB Streptococcus mitis NCTC 12261

37.778

99.338

0.375
  comB Streptococcus pneumoniae D39

37.556

99.338

0.373
  comB Streptococcus pneumoniae R6

37.556

99.338

0.373
  comB Streptococcus pneumoniae Rx1

37.556

99.338

0.373
  comB Streptococcus gordonii str. Challis substr. CH1

37.029

99.558

0.369
  comB Streptococcus mitis SK321

37.111

99.338

0.369