Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilH   Type   Machinery gene
Locus tag   NLP_RS18245 Genome accession   NZ_CP026692
Coordinates   4134666..4135031 (+) Length   121 a.a.
NCBI ID   WP_069073698.1    Uniprot ID   A0A2D0HCN5
Organism   Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' strain 5183     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 4129666..4140031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLP_RS18225 (NLP_3548) - 4130339..4130638 (+) 300 WP_104907621.1 type II toxin-antitoxin system HigB family toxin -
  NLP_RS18230 (NLP_3549) - 4130622..4131023 (+) 402 WP_104907622.1 hypothetical protein -
  NLP_RS18235 (NLP_3550) hmpF 4131080..4132840 (-) 1761 WP_104907623.1 pilus motility taxis protein HmpF -
  NLP_RS18240 (NLP_3551) - 4133224..4134402 (+) 1179 WP_104907624.1 response regulator -
  NLP_RS18245 (NLP_3552) pilH 4134666..4135031 (+) 366 WP_069073698.1 response regulator Machinery gene
  NLP_RS18250 (NLP_3553) - 4135045..4135575 (+) 531 WP_104907625.1 chemotaxis protein CheW -
  NLP_RS18255 (NLP_3554) - 4135590..4138538 (+) 2949 WP_104909921.1 methyl-accepting chemotaxis protein -

Sequence


Protein


Download         Length: 121 a.a.        Molecular weight: 13350.52 Da        Isoelectric Point: 4.8604

>NTDB_id=271745 NLP_RS18245 WP_069073698.1 4134666..4135031(+) (pilH) [Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' strain 5183]
MSTVLIVEDSIAQREMITDLLKATGLTVTHASDGLEALEAIQIAPPDLVVLDIVMPRMNGYEVCRRLKSDPKTQNVPVVM
CSSKGEEFDRYWGMKQGADAYIAKPFQPTELVGTVKQLLRG

Nucleotide


Download         Length: 366 bp        

>NTDB_id=271745 NLP_RS18245 WP_069073698.1 4134666..4135031(+) (pilH) [Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' strain 5183]
ATGAGCACAGTTCTGATTGTGGAAGACAGTATCGCGCAAAGGGAGATGATTACAGACCTCCTGAAAGCAACTGGCCTAAC
AGTTACCCACGCTAGTGACGGATTAGAAGCATTAGAGGCAATTCAAATAGCACCTCCAGATTTAGTGGTATTAGATATTG
TCATGCCCCGAATGAACGGCTACGAAGTTTGTCGGCGGTTAAAATCCGATCCAAAAACCCAAAATGTCCCAGTGGTTATG
TGTTCTTCTAAAGGTGAAGAATTCGATCGCTATTGGGGCATGAAGCAAGGTGCAGACGCTTACATAGCCAAACCGTTTCA
ACCAACTGAGTTGGTAGGAACAGTCAAACAACTGCTGCGAGGATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A2D0HCN5

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Synechocystis sp. PCC 6803

76.86

100

0.769

  micA Streptococcus pneumoniae Cp1015

39.167

99.174

0.388

  pilG Acinetobacter baumannii strain A118

41.228

94.215

0.388

  vicR Streptococcus mutans UA159

38.333

99.174

0.38

  pilL-C Synechocystis sp. PCC 6803

37.5

99.174

0.372


Multiple sequence alignment