Detailed information NTG0271464

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: C4N11_RS10760
• Genome accession: NZ_CP026670
• Coordinates: 2008755..2009216 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain endophthalmitis isolate 335
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2003755..2014216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C4N11_RS10730 (C4N11_10730)	-	2004060..2004884 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
C4N11_RS10735 (C4N11_10735)	rnpA	2004859..2005230 (-)	372	WP_000739246.1	ribonuclease P protein component	-
C4N11_RS12850	-	2005247..2005378 (-)	132	WP_000768904.1	hypothetical protein	-
C4N11_RS10740 (C4N11_10740)	-	2005379..2006569 (-)	1191	WP_000167766.1	acetate kinase	-
C4N11_RS10745 (C4N11_10745)	comYH	2006620..2007573 (-)	954	WP_000345133.1	class I SAM-dependent methyltransferase	Machinery gene
C4N11_RS10750 (C4N11_10750)	-	2007634..2008228 (-)	595	Protein_2003	class I SAM-dependent methyltransferase	-
C4N11_RS10755 (C4N11_10755)	comGG/cglG	2008331..2008777 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
C4N11_RS10760 (C4N11_10760)	comGF/cglF	2008755..2009216 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
C4N11_RS10765 (C4N11_10765)	comGE/cglE	2009179..2009481 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
C4N11_RS10770 (C4N11_10770)	comGD/cglD	2009444..2009848 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
C4N11_RS10775 (C4N11_10775)	comGC/cglC	2009841..2010167 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
C4N11_RS10780 (C4N11_10780)	comGB/cglB	2010169..2011185 (-)	1017	WP_078134418.1	competence type IV pilus assembly protein ComGB	Machinery gene
C4N11_RS10785 (C4N11_10785)	comGA/cglA/cilD	2011133..2012074 (-)	942	WP_000249573.1	competence type IV pilus ATPase ComGA	Machinery gene
C4N11_RS10790 (C4N11_10790)	-	2012150..2012515 (-)	366	WP_000286415.1	DUF1033 family protein	-
C4N11_RS10795 (C4N11_10795)	-	2012666..2013724 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=271464 C4N11_RS10760 WP_000250539.1 2008755..2009216(-) (comGF/cglF) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=271464 C4N11_RS10760 WP_000250539.1 2008755..2009216(-) (comGF/cglF) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915