Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   C4N11_RS10745 Genome accession   NZ_CP026670
Coordinates   2006620..2007573 (-) Length   317 a.a.
NCBI ID   WP_000345133.1    Uniprot ID   A0A0T8FEM8
Organism   Streptococcus pneumoniae strain endophthalmitis isolate 335     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2001620..2012573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4N11_RS10720 (C4N11_10720) - 2002381..2003004 (-) 624 WP_000932661.1 hypothetical protein -
  C4N11_RS10725 (C4N11_10725) jag 2003055..2004041 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  C4N11_RS10730 (C4N11_10730) - 2004060..2004884 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  C4N11_RS10735 (C4N11_10735) rnpA 2004859..2005230 (-) 372 WP_000739246.1 ribonuclease P protein component -
  C4N11_RS12850 - 2005247..2005378 (-) 132 WP_000768904.1 hypothetical protein -
  C4N11_RS10740 (C4N11_10740) - 2005379..2006569 (-) 1191 WP_000167766.1 acetate kinase -
  C4N11_RS10745 (C4N11_10745) comYH 2006620..2007573 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  C4N11_RS10750 (C4N11_10750) - 2007634..2008228 (-) 595 Protein_2003 class I SAM-dependent methyltransferase -
  C4N11_RS10755 (C4N11_10755) comGG/cglG 2008331..2008777 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  C4N11_RS10760 (C4N11_10760) comGF/cglF 2008755..2009216 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  C4N11_RS10765 (C4N11_10765) comGE/cglE 2009179..2009481 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  C4N11_RS10770 (C4N11_10770) comGD/cglD 2009444..2009848 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  C4N11_RS10775 (C4N11_10775) comGC/cglC 2009841..2010167 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  C4N11_RS10780 (C4N11_10780) comGB/cglB 2010169..2011185 (-) 1017 WP_078134418.1 competence type IV pilus assembly protein ComGB Machinery gene
  C4N11_RS10785 (C4N11_10785) comGA/cglA/cilD 2011133..2012074 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  C4N11_RS10790 (C4N11_10790) - 2012150..2012515 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35721.90 Da        Isoelectric Point: 4.2665

>NTDB_id=271462 C4N11_RS10745 WP_000345133.1 2006620..2007573(-) (comYH) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=271462 C4N11_RS10745 WP_000345133.1 2006620..2007573(-) (comYH) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGTTAAACCAGGTCAAAGACAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGTCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCTCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8FEM8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment