Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   C2E46_RS03765 Genome accession   NZ_CP026082
Coordinates   710613..711323 (+) Length   236 a.a.
NCBI ID   WP_000722052.1    Uniprot ID   X5K3L1
Organism   Streptococcus agalactiae strain YZ1605     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 705613..716323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS03745 (C2E46_03860) - 707336..707986 (-) 651 WP_000100034.1 amino acid ABC transporter permease -
  C2E46_RS03750 (C2E46_03865) - 707998..708693 (-) 696 WP_000173639.1 amino acid ABC transporter permease -
  C2E46_RS03755 (C2E46_03870) - 708706..709506 (-) 801 WP_000946171.1 transporter substrate-binding domain-containing protein -
  C2E46_RS03760 (C2E46_03875) - 709518..710273 (-) 756 WP_161501822.1 amino acid ABC transporter ATP-binding protein -
  C2E46_RS03765 (C2E46_03880) vicR 710613..711323 (+) 711 WP_000722052.1 response regulator YycF Regulator
  C2E46_RS03770 (C2E46_03885) vicK 711316..712665 (+) 1350 WP_001065469.1 cell wall metabolism sensor histidine kinase VicK Regulator
  C2E46_RS03775 (C2E46_03890) vicX 712669..713478 (+) 810 WP_001289498.1 MBL fold metallo-hydrolase Regulator
  C2E46_RS03780 (C2E46_03895) - 713481..713849 (+) 369 WP_000719385.1 YbaN family protein -
  C2E46_RS03785 (C2E46_03900) rnc 714025..714711 (+) 687 WP_000661525.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27063.90 Da        Isoelectric Point: 4.8246

>NTDB_id=266895 C2E46_RS03765 WP_000722052.1 710613..711323(+) (vicR) [Streptococcus agalactiae strain YZ1605]
MKKILIVDDEKPISDIIKFNLTKEGYETATAFDGREALVQYAEFQPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEESAQNASSDITIGELQILPDAFIAKKRGEEIE
LTHREFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=266895 C2E46_RS03765 WP_000722052.1 710613..711323(+) (vicR) [Streptococcus agalactiae strain YZ1605]
ATGAAAAAAATACTTATCGTTGATGATGAAAAACCAATTTCAGATATTATCAAATTTAATTTAACCAAAGAAGGATATGA
GACGGCGACAGCTTTCGATGGCCGTGAAGCTTTAGTACAATATGCAGAATTTCAACCAGATTTAATCATTTTGGATTTAA
TGCTCCCTGAACTAGATGGTTTAGAAGTGGCTAAGGAAGTTCGTAAAACCAGCCATATTCCTATTATTATGCTTTCTGCA
AAAGACAGTGAGTTTGACAAAGTCATTGGTTTAGAAATCGGTGCAGATGATTATGTTACTAAACCTTTTTCAAATCGTGA
ACTTTTGGCACGGGTCAAAGCACATTTACGACGTACTGAAAATATTGAAACAGCTGTAGCAGAAGAAAGTGCTCAAAATG
CTTCTTCAGATATTACTATTGGTGAGTTGCAAATTTTACCAGACGCCTTTATTGCTAAGAAACGTGGCGAAGAAATTGAA
TTAACGCACCGAGAATTTGAATTACTTCACCATTTAGCGACACATATCGGACAAGTCATGACACGCGAACATTTATTGGA
AACAGTTTGGGGATATGATTATTTTGGAGATGTCCGTACAGTTGATGTGACGGTGAGACGTTTACGTGAAAAGATTGAAG
ATACTCCTGGTCGTCCAGAATATATTTTGACTCGACGTGGTGTAGGTTATTACATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X5K3L1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

77.778

99.153

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.983

98.305

0.462
  covR Streptococcus salivarius strain HSISS4

44.635

98.729

0.441
  scnR Streptococcus mutans UA159

38.559

100

0.386

Multiple sequence alignment