Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   C2E46_RS02095 Genome accession   NZ_CP026082
Coordinates   369318..371273 (+) Length   651 a.a.
NCBI ID   WP_017643472.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain YZ1605     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 364318..376273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS02080 (C2E46_02130) fmt 366296..367231 (+) 936 WP_000163893.1 methionyl-tRNA formyltransferase -
  C2E46_RS02085 (C2E46_02135) rsmB 367221..368543 (+) 1323 WP_001262608.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  C2E46_RS02090 (C2E46_02140) - 368581..369318 (+) 738 WP_000406233.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  C2E46_RS02095 (C2E46_02145) pknB 369318..371273 (+) 1956 WP_017643472.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  C2E46_RS02100 (C2E46_02150) liaF 371433..372128 (+) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  C2E46_RS02105 (C2E46_02155) - 372125..373144 (+) 1020 WP_161501796.1 sensor histidine kinase -
  C2E46_RS02110 (C2E46_02160) - 373137..373778 (+) 642 WP_000357891.1 response regulator transcription factor -
  C2E46_RS02115 (C2E46_02165) - 373820..375220 (+) 1401 WP_000339135.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  C2E46_RS02120 (C2E46_02170) - 375222..375578 (+) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 70753.50 Da        Isoelectric Point: 9.6759

>NTDB_id=266887 C2E46_RS02095 WP_017643472.1 369318..371273(+) (pknB) [Streptococcus agalactiae strain YZ1605]
MIQIGKLFAGRYRILKSIGRGGMADVYLARDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELTHPNIVAIRDIG
EEDGQQFLVMEYVDGFDLKKYIQDNAPPSNNEVVRIMNEVLSAMSLAHQKGIVHRDLKPQNILLTKKGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENKSVP
QALENIVIKATAKKLTDRYKTTYEMGRDLSTALSSTRHREPKLVFNDTESTKTLPKVTSTVSSLTTEQLLRNQKQAKTTE
KITPDSASNDKTKSKKKASHRLLGTIMKLFFALCVVGIIVFAYKILVSPTTIRVPDVSNKTVAQAKMTLENSGLKVGAIR
NIESDSVSEGLVVKTDPAAGRSRREGAKVNLYIATPNKSFTLGNYKEHNYKDILKDLQGKGVKKSLIKVKRKINNDYTTG
TILAQSLPEGTSFNPDGNKKLTLTVAVNDPMIMPDVTGMTVGEVIETLTDLGLDADNLVFYQMQNGVYQAVVTPPSSSKI
ASQDPYYGGEVGLRRGDKVKLYLLGSKTTNNSSSTPIDSSASSSTGTTTSDSVSSSTDASTSDSSSTSTSSSTLPSDSTT
NTGTANNPLTQ

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=266887 C2E46_RS02095 WP_017643472.1 369318..371273(+) (pknB) [Streptococcus agalactiae strain YZ1605]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTTAAATCAATCGGACGAGGTGGAATGGCGGATGTTTA
TCTAGCTCGAGATCTAATTTTAGATAATGAAGAGGTCGCAATAAAAGTATTGCGAACCAATTATCAAACAGATCAGATTG
CGGTTGCTCGCTTCCAGAGAGAAGCACGAGCAATGGCTGAGCTGACACATCCTAATATTGTCGCTATTCGTGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATGTTGATGGATTCGATTTAAAAAAGTATATTCAAGACAATGCACC
CCCATCAAATAATGAAGTTGTTCGAATCATGAATGAAGTCCTTTCAGCCATGTCACTGGCACATCAGAAAGGTATCGTAC
ACCGTGATTTAAAACCTCAAAATATTTTATTAACTAAAAAAGGGACTGTAAAAGTTACAGATTTCGGTATTGCGGTAGCG
TTTGCTGAAACTAGTTTAACGCAAACGAATTCTATGTTAGGTAGTGTTCATTATTTATCACCAGAGCAGGCGCGTGGGTC
AAAAGCGACTGTTCAGAGTGATATTTATGCCATGGGAATCATGCTTTTTGAAATGTTAACTGGCCATATTCCTTATGATG
GGGATAGTGCAGTTACTATTGCCCTACAGCACTTCCAAAAACCACTACCATCAATCCTTGCAGAAAATAAAAGCGTTCCA
CAAGCTTTGGAAAACATTGTCATTAAAGCAACAGCTAAAAAGCTAACAGATCGCTATAAGACAACTTATGAGATGGGACG
TGATTTATCAACTGCTCTAAGCTCGACACGTCACCGTGAACCAAAACTTGTTTTTAATGATACTGAGAGTACTAAGACAC
TACCAAAAGTAACATCTACAGTATCATCTTTAACAACAGAACAACTGTTGCGTAATCAAAAACAGGCCAAAACAACAGAA
AAAATAACTCCTGATTCTGCGAGTAACGATAAAACGAAGTCTAAAAAGAAGGCTTCTCATCGACTTCTTGGTACAATCAT
GAAATTATTCTTTGCACTCTGTGTTGTAGGAATAATTGTATTTGCTTATAAAATTTTAGTAAGTCCTACGACTATTCGTG
TTCCAGATGTTAGCAACAAAACAGTAGCTCAAGCAAAAATGACATTGGAAAATTCTGGATTGAAAGTAGGAGCTATTCGT
AATATTGAGAGTGATAGTGTTTCAGAAGGCCTTGTCGTAAAAACAGACCCTGCTGCAGGACGTTCTCGCAGAGAAGGGGC
TAAAGTTAATCTTTATATTGCCACTCCAAACAAGAGTTTCACTCTAGGTAATTATAAGGAACATAATTACAAAGATATCC
TCAAAGATCTTCAAGGCAAAGGTGTTAAAAAATCTCTAATCAAGGTTAAGCGTAAAATTAATAATGATTATACTACTGGT
ACAATCTTAGCACAGTCGCTTCCAGAAGGAACATCTTTTAATCCTGATGGTAATAAGAAATTAACACTTACGGTTGCTGT
TAATGATCCAATGATTATGCCTGATGTAACAGGTATGACAGTTGGAGAAGTAATAGAAACTTTGACAGACCTCGGATTAG
ATGCAGATAATCTTGTCTTCTATCAAATGCAAAATGGCGTTTATCAAGCAGTAGTAACACCTCCATCTTCAAGTAAGATA
GCAAGTCAGGATCCTTATTACGGAGGAGAAGTTGGATTAAGGAGAGGAGATAAGGTTAAGCTGTATCTTCTTGGTTCTAA
AACAACGAATAACTCATCATCTACGCCAATAGATTCTTCGGCTTCAAGCTCAACAGGAACAACTACCTCGGATTCTGTAA
GCTCATCAACGGATGCTAGCACTTCTGATAGTAGTAGCACTTCTACAAGTAGTTCAACACTACCAAGTGATAGTACAACT
AATACAGGAACAGCTAACAATCCATTAACTCAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-254)

PASTA domain (PASTA)

(511-583)

PASTA domain (PASTA)

(373-434)

PASTA domain (PASTA)

(441-506)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

60.788

89.708

0.545
  stkP/pknB Streptococcus salivarius strain HSISS4

60.727

88.786

0.539
  stkP Streptococcus pneumoniae TIGR4

59.417

79.109

0.47
  stkP Streptococcus pneumoniae D39

59.223

79.109

0.469
  stkP Streptococcus pneumoniae R6

59.223

79.109

0.469
  stkP Streptococcus pneumoniae Rx1

59.029

79.109

0.467

Multiple sequence alignment