Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LACR_RS11800 Genome accession   NC_008527
Coordinates   2266690..2267913 (+) Length   407 a.a.
NCBI ID   WP_011677195.1    Uniprot ID   A0AA34XLX6
Organism   Lactococcus cremoris subsp. cremoris SK11     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2261690..2272913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LACR_RS11775 (LACR_2434) - 2262805..2263608 (-) 804 WP_011677190.1 phosphatidate cytidylyltransferase -
  LACR_RS11780 (LACR_2435) - 2263608..2264342 (-) 735 WP_011677191.1 isoprenyl transferase -
  LACR_RS11785 (LACR_2436) yajC 2264692..2265024 (-) 333 WP_011677192.1 preprotein translocase subunit YajC -
  LACR_RS11790 (LACR_2437) - 2265119..2265817 (-) 699 Protein_2297 DNA alkylation repair protein -
  LACR_RS11795 (LACR_2438) rlmH 2265835..2266314 (-) 480 WP_011677194.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LACR_RS11800 (LACR_2439) htrA 2266690..2267913 (+) 1224 WP_011677195.1 S1C family serine protease Regulator
  LACR_RS11805 (LACR_2440) - 2268035..2269033 (+) 999 WP_011677196.1 glycosyltransferase family 4 protein -
  LACR_RS11810 (LACR_2441) - 2269171..2270511 (+) 1341 WP_011677197.1 glycosyltransferase family 4 protein -
  LACR_RS11815 (LACR_2442) - 2270619..2270843 (+) 225 WP_011677198.1 YkuJ family protein -
  LACR_RS11820 (LACR_2443) - 2270982..2271986 (+) 1005 WP_011677199.1 hypothetical protein -
  LACR_RS11825 (LACR_2444) - 2272043..2272795 (-) 753 WP_014573352.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41564.97 Da        Isoelectric Point: 5.7132

>NTDB_id=26585 LACR_RS11800 WP_011677195.1 2266690..2267913(+) (htrA) [Lactococcus cremoris subsp. cremoris SK11]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKATVVGYDEYTDLAVL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGVVVYSVQAGHPAATAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSDLET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=26585 LACR_RS11800 WP_011677195.1 2266690..2267913(+) (htrA) [Lactococcus cremoris subsp. cremoris SK11]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTTGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAACCGCTCAAATACAACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTCACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACGGCTTGCAACTTTCCAGTGAGGG
TTCTGGTGTTATTTATAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCTGGAAATAGTTCCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGATGAATACACTGACCTTGCCGTTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
AGTCGGCTCACCTTTAGGTAGCCAGTTTGCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACTT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCGGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACCGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATCCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCTGCCTTAGGTATTCGTATGGTTGACCTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGAGTGGTTGTCTACTCTGTTCAAGCGGGTCATCCTGCTGCCACAGCTGGTCTGAAAGCTGGCGATGTGAT
AACGAAGGTGGGAGATACCGCCGTTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTTAAACTCTCTAAATCAACAAGCGATTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(250-395)

PDZ domain (PDZ_2)

(295-391)

Trypsin-like peptidase domain (Trypsin_2)

(107-252)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

55.128

95.823

0.528
  htrA Streptococcus mitis NCTC 12261

55.875

94.103

0.526
  htrA Streptococcus pneumoniae R6

58.14

84.521

0.491
  htrA Streptococcus pneumoniae TIGR4

58.14

84.521

0.491
  htrA Streptococcus pneumoniae D39

58.14

84.521

0.491
  htrA Streptococcus pneumoniae Rx1

58.14

84.521

0.491
  htrA Streptococcus mutans UA159

53.388

90.663

0.484

Multiple sequence alignment