Detailed information NTG0026568

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LACR_RS09390
• Genome accession: NC_008527
• Coordinates: 1835353..1836624 (-)
• Length: 423 a.a.
• NCBI ID: WP_324187454.1
• Uniprot ID: -
• Organism: Lactococcus cremoris subsp. cremoris SK11
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1833880..1834770	1835353..1836624	flank	583

Gene organization within MGE regions

Location: 1833880..1836624

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LACR_RS09385 (LACR_1943)	-	1833880..1834770 (-)	891	WP_011676771.1	IS982 family transposase	-
LACR_RS14585	comEC	1834847..1835356 (-)	510	WP_021165649.1	MBL fold metallo-hydrolase	Machinery gene
LACR_RS09390	comEC	1835353..1836624 (-)	1272	WP_324187454.1	ComEC/Rec2 family competence protein	Machinery gene

Sequence

Protein

• Length: 423 a.a.
• Molecular weight: 49066.18 Da
• Isoelectric Point: 9.7194

>NTDB_id=26568 LACR_RS09390 WP_324187454.1 1835353..1836624(-) (comEC) [Lactococcus cremoris subsp. cremoris SK11]
MIPILIVFAVFFLLINSLSIRDNENQPKNLSKIELIPDTIQFNGDLLSFQGRMNGQKYQVYDTLKSLKEKGFYQNLSQNC
QLSFTGNLEIPETQRNFNGFDDQKYLTSQNIYRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFG
FLSKDFNQMSDIYSSLGIIHLFALSGMQVNFFIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNI
RLTSLDNIAVTTLVLMLISPKFLLTTGGQLTLFYAFVISMLNHPFSNLNGLKKVLTESSVLSLCVLPLLIFDFHIFQPLS
ILLTIIFGFLFDFMLLPLLLCCFLISFLGFSLNLNYIFQILEWLVYKVDLPLHYPFVLGKPSSLELIILFVLIGLFVDSF
SHKKRRFFLIGFIFLFFSSLKIQ

Nucleotide

• Length: 1272 bp

>NTDB_id=26568 LACR_RS09390 WP_324187454.1 1835353..1836624(-) (comEC) [Lactococcus cremoris subsp. cremoris SK11]
ATGATTCCGATATTAATTGTTTTTGCTGTATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACC
AAAAAATCTCTCAAAAATTGAATTAATTCCAGATACAATCCAATTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGA
ATGGACAAAAATATCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAGGGTTTTATCAGAACTTAAGTCAAAATTGT
CAGTTAAGTTTCACAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAAC
TAGTCAAAATATCTATCGACAGATTACCATCCAACAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTT
TAAGGCGAAAGGCAATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACAGGTTTGCTTTTTGGC
TTTTTAAGTAAGGATTTTAATCAGATGAGCGATATTTACAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAAT
GCAAGTAAATTTTTTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTC
AAATTCCATTTTCTATTTTTTATGCTTTTATGACGGGATTATCGGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATT
CGTCTGACTTCTTTGGATAATATCGCAGTTACGACATTAGTTTTGATGCTCATAAGTCCAAAATTTTTACTGACGACTGG
TGGTCAGCTTACCTTGTTTTATGCTTTTGTCATTTCGATGCTTAATCATCCTTTTTCTAATTTAAATGGATTGAAAAAAG
TGCTGACAGAATCATCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTCCATATTTTTCAGCCTCTTTCA
ATATTATTAACAATTATATTTGGTTTTCTTTTTGATTTTATGTTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATT
TTTGGGATTTTCGCTCAATTTAAATTATATTTTTCAAATTCTAGAATGGCTAGTTTATAAAGTTGATTTACCCTTACATT
ACCCCTTTGTTTTGGGGAAACCTAGTTCACTCGAATTAATTATTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTT
TCTCATAAAAAAAGGAGATTTTTTTTAATTGGATTTATATTTTTATTTTTTTCATCACTAAAAATCCAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (56-122)

• Competence protein (Competence) (157-397)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	96.882	98.582	0.955
comEC/celB	Streptococcus mitis SK321	46.253	91.489	0.423
comEC/celB	Streptococcus mitis NCTC 12261	45.736	91.489	0.418
comEC/celB	Streptococcus pneumoniae TIGR4	45.736	91.489	0.418
comEC/celB	Streptococcus pneumoniae Rx1	44.961	91.489	0.411
comEC/celB	Streptococcus pneumoniae D39	44.961	91.489	0.411
comEC/celB	Streptococcus pneumoniae R6	44.961	91.489	0.411