Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   SPYM_RS00660 Genome accession   NC_009332
Coordinates   106088..106516 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes str. Manfredo     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 101088..111516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS00640 (SpyM50083) - 103419..103784 (+) 366 WP_002986560.1 DUF1033 family protein -
  SPYM_RS00645 (SpyM50084) comGA 103877..104815 (+) 939 WP_011888534.1 competence type IV pilus ATPase ComGA Machinery gene
  SPYM_RS00650 (SpyM50085) comGB 104751..105785 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPYM_RS00655 (SpyM50086) comGC 105787..106113 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  SPYM_RS00660 (SpyM50087) comGD 106088..106516 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPYM_RS00665 (SpyM50088) comGE 106473..106757 (+) 285 WP_041174183.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPYM_RS00670 (SpyM50089) comGF 106750..107184 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPYM_RS00675 (SpyM50090) comGG 107168..107494 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  SPYM_RS00680 (SpyM50091) comGH 107592..108545 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  SPYM_RS00685 (SpyM50092) - 108604..109800 (+) 1197 WP_011888536.1 acetate kinase -
  SPYM_RS00690 (SpyM50093) - 109987..110295 (+) 309 WP_011017251.1 hypothetical protein -
  SPYM_RS00695 (SpyM50094) proC 110378..111148 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=26439 SPYM_RS00660 WP_002986548.1 106088..106516(+) (comGD) [Streptococcus pyogenes str. Manfredo]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=26439 SPYM_RS00660 WP_002986548.1 106088..106516(+) (comGD) [Streptococcus pyogenes str. Manfredo]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366

Multiple sequence alignment