Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DV130_RS01170 Genome accession   NZ_CP031248
Coordinates   212302..212943 (+) Length   213 a.a.
NCBI ID   WP_078130870.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26365     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 207302..217943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS01140 - 207516..208925 (+) 1410 WP_050072240.1 hypothetical protein -
  DV130_RS01145 - 208930..209418 (+) 489 Protein_219 phosphatidylglycerophosphatase A -
  DV130_RS01150 - 209706..210113 (+) 408 WP_000216067.1 cytidine deaminase -
  DV130_RS01155 - 210145..211062 (+) 918 WP_050209296.1 dihydrodipicolinate synthase family protein -
  DV130_RS01160 - 211089..211283 (+) 195 Protein_222 ROK family protein -
  DV130_RS01165 - 211433..212029 (-) 597 WP_000547415.1 transposase -
  DV130_RS12815 - 211990..212177 (+) 188 Protein_224 hypothetical protein -
  DV130_RS01170 comA 212302..212943 (+) 642 WP_078130870.1 ATP-binding cassette domain-containing protein Regulator
  DV130_RS12060 - 212956..213126 (+) 171 WP_000711943.1 hypothetical protein -
  DV130_RS01185 gdhA 213632..214978 (-) 1347 WP_000199566.1 NADP-specific glutamate dehydrogenase -
  DV130_RS12065 - 215319..215543 (+) 225 Protein_228 hypothetical protein -
  DV130_RS01190 - 215646..216175 (+) 530 Protein_229 transposase -
  DV130_RS01195 - 216172..216390 (+) 219 WP_000028153.1 hypothetical protein -
  DV130_RS01200 - 216447..216689 (-) 243 WP_000710764.1 type B 50S ribosomal protein L31 -
  DV130_RS01205 - 216785..217720 (-) 936 WP_000401770.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23645.50 Da        Isoelectric Point: 9.4837

>NTDB_id=263335 DV130_RS01170 WP_078130870.1 212302..212943(+) (comA) [Streptococcus pneumoniae strain M26365]
MTIESGQRIALVGQPGSGKSLLSKIPSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEV
TSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
QGCTQIIVAHRLSTIKDADIIFVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK

Nucleotide


Download         Length: 642 bp        

>NTDB_id=263335 DV130_RS01170 WP_078130870.1 212302..212943(+) (comA) [Streptococcus pneumoniae strain M26365]
TTGACTATTGAGTCAGGACAGAGAATTGCACTAGTCGGTCAACCGGGGTCAGGAAAAAGTCTATTATCAAAAATACCATC
AAGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTC
AAAATTTAGGAGTAGTTCCACAGGATTCATTTTTATTGAACCGAAGTATTCTTGATAATATAACTTTAAAGCACGAAGTT
ACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATAC
TATCATCTCAGAGATGGGGTCAAATATTTCAGGTGGGCAAAGGCAACGGATAGCACTGGCACGTGCATTAATAAATAATC
CTAGTATTGTAATTTTAGATGAAGCAACTAGTGCTTTAGACACTATTAATGAGGAAAGAATAACAAAGTATATAAAAAGT
CAGGGCTGTACTCAAATAATTGTAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTTTTGTAATGAAAGGTGG
TAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGAGAGTACTACAGCTTATATACAAAAAGGAAAT
GA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(1-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

42.381

98.592

0.418
  comA Streptococcus mitis SK321

41.905

98.592

0.413
  comA/nlmT Streptococcus mutans UA159

41.509

99.531

0.413
  comA Streptococcus gordonii str. Challis substr. CH1

41.038

99.531

0.408
  comA Streptococcus pneumoniae R6

40.952

98.592

0.404
  comA Streptococcus pneumoniae Rx1

40.952

98.592

0.404
  comA Streptococcus pneumoniae D39

40.952

98.592

0.404
  comA Streptococcus pneumoniae TIGR4

40

98.592

0.394
  rcrQ Streptococcus mutans UA159

36.62

100

0.366

Multiple sequence alignment