Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   DV129_RS06925 Genome accession   NZ_CP031247
Coordinates   1292289..1292729 (+) Length   146 a.a.
NCBI ID   WP_000861968.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M23734     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1287289..1297729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS06900 ribE 1287481..1288116 (+) 636 WP_000493842.1 riboflavin synthase -
  DV129_RS06905 - 1288136..1289341 (+) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  DV129_RS06910 ribE 1289342..1289809 (+) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  DV129_RS06915 hexB 1290134..1292083 (-) 1950 WP_000018164.1 DNA mismatch repair endonuclease MutL Machinery gene
  DV129_RS06925 brsR 1292289..1292729 (+) 441 WP_000861968.1 LytTR family DNA-binding domain-containing protein Regulator
  DV129_RS06930 - 1292726..1293184 (+) 459 WP_000745054.1 DUF3021 domain-containing protein -
  DV129_RS06935 - 1293494..1294756 (+) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  DV129_RS06945 nrdI 1295049..1295519 (-) 471 WP_000849618.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  DV129_RS06950 - 1295597..1296130 (-) 534 WP_000729037.1 hypothetical protein -
  DV129_RS06955 - 1296182..1297468 (-) 1287 WP_000278864.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17137.81 Da        Isoelectric Point: 5.9797

>NTDB_id=263266 DV129_RS06925 WP_000861968.1 1292289..1292729(+) (brsR) [Streptococcus pneumoniae strain M23734]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=263266 DV129_RS06925 WP_000861968.1 1292289..1292729(+) (brsR) [Streptococcus pneumoniae strain M23734]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment