Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DV129_RS01300 Genome accession   NZ_CP031247
Coordinates   228742..229383 (+) Length   213 a.a.
NCBI ID   WP_000151483.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M23734     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 223742..234383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS01270 - 224438..224845 (+) 408 WP_000216069.1 cytidine deaminase -
  DV129_RS01275 - 224877..225794 (+) 918 WP_001281465.1 dihydrodipicolinate synthase family protein -
  DV129_RS01280 - 225821..226015 (+) 195 Protein_239 ROK family protein -
  DV129_RS01285 - 226165..226620 (-) 456 WP_000459732.1 transposase -
  DV129_RS01290 - 226797..228143 (+) 1347 WP_001845280.1 IS1380-like element ISSpn5 family transposase -
  DV129_RS12575 - 228430..228617 (+) 188 Protein_242 hypothetical protein -
  DV129_RS01300 comA 228742..229383 (+) 642 WP_000151483.1 ATP-binding cassette domain-containing protein Regulator
  DV129_RS11845 - 229396..229566 (+) 171 WP_000711943.1 hypothetical protein -
  DV129_RS01315 gdhA 230062..231408 (-) 1347 WP_000199558.1 NADP-specific glutamate dehydrogenase -
  DV129_RS01320 - 231815..232396 (+) 582 Protein_246 winged helix-turn-helix domain-containing protein -
  DV129_RS01325 - 232399..233411 (+) 1013 Protein_247 Dyp-type peroxidase -
  DV129_RS01330 - 233386..233964 (+) 579 WP_000252109.1 hypothetical protein -
  DV129_RS01335 - 234021..234263 (-) 243 WP_000710764.1 type B 50S ribosomal protein L31 -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23486.26 Da        Isoelectric Point: 9.2387

>NTDB_id=263217 DV129_RS01300 WP_000151483.1 228742..229383(+) (comA) [Streptococcus pneumoniae strain M23734]
MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEV
TSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK

Nucleotide


Download         Length: 642 bp        

>NTDB_id=263217 DV129_RS01300 WP_000151483.1 228742..229383(+) (comA) [Streptococcus pneumoniae strain M23734]
TTGACTATTGAGTCAGGACAGAGAATTGCACTAGTCGGTCAACCGGGGTCAGGAAAAAGTACATTATCAAAAATACCATC
AGGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTC
AAAATTTAGGAGTAGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAACATAACTTTAAAGCACGAAGTT
ACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATAC
TATCATCTCAGAGATGGGTTCAAATATTTCAGGTGGTCAAAGACAACGGATAGCACTGGCACGTGCATTAATAAATAATC
CTAGTATTGTAATTTTAGATGAAGCAACTAGTGCTTTAGACACTATTAATGAGGAAAGAATAACAAAGTATATAAAAAGT
CAGGGCTGTACTCAAATAATTGTAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTGTTGTAATGAAAGGTGG
TAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGAGAGTACTACAGCTTATATACAAAAAGGAAAT
GA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(1-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

43.333

98.592

0.427
  comA Streptococcus mitis SK321

42.857

98.592

0.423
  comA Streptococcus gordonii str. Challis substr. CH1

41.981

99.531

0.418
  comA/nlmT Streptococcus mutans UA159

41.981

99.531

0.418
  comA Streptococcus pneumoniae R6

41.905

98.592

0.413
  comA Streptococcus pneumoniae Rx1

41.905

98.592

0.413
  comA Streptococcus pneumoniae D39

41.905

98.592

0.413
  comA Streptococcus pneumoniae TIGR4

40.952

98.592

0.404
  rcrQ Streptococcus mutans UA159

36.62

100

0.366