Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   C6669_RS19550 Genome accession   NZ_CP031134
Coordinates   3765925..3766581 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CFSAN064035     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3760925..3771581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6669_RS19520 (C6669_19520) dcyD 3761804..3762790 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  C6669_RS19525 (C6669_19525) tcyL 3762805..3763473 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  C6669_RS19530 (C6669_19530) tcyN 3763470..3764222 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  C6669_RS19535 (C6669_19535) sdiA 3764452..3765174 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  C6669_RS19540 (C6669_19540) yecF 3765242..3765466 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  C6669_RS29230 yecU 3765453..3765629 (-) 177 WP_000590344.1 protein YecU -
  C6669_RS30090 (C6669_19545) - 3765667..3765783 (-) 117 WP_001302039.1 hypothetical protein -
  C6669_RS19550 (C6669_19550) letA 3765925..3766581 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  C6669_RS19555 (C6669_19555) uvrC 3766578..3768410 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  C6669_RS19560 (C6669_19560) pgsA 3768467..3769015 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  C6669_RS19580 (C6669_19580) yecA 3769665..3770330 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=262399 C6669_RS19550 WP_000611335.1 3765925..3766581(+) (letA) [Escherichia coli strain CFSAN064035]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=262399 C6669_RS19550 WP_000611335.1 3765925..3766581(+) (letA) [Escherichia coli strain CFSAN064035]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment