Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   C0J00_RS07955 Genome accession   NZ_CP025536
Coordinates   1563780..1565663 (-) Length   627 a.a.
NCBI ID   WP_104968362.1    Uniprot ID   A0A2L0D633
Organism   Streptococcus pluranimalium strain TH11417     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1558780..1570663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS07925 (C0J00_07930) tnpA 1558809..1559320 (-) 512 Protein_1512 IS200/IS605 family transposase -
  C0J00_RS07930 (C0J00_07935) - 1559484..1559843 (-) 360 WP_104968357.1 S1 RNA-binding domain-containing protein -
  C0J00_RS10680 (C0J00_07940) - 1559843..1561243 (-) 1401 WP_104968358.1 Cof-type HAD-IIB family hydrolase -
  C0J00_RS07940 (C0J00_07945) - 1561291..1561929 (-) 639 WP_104968359.1 response regulator transcription factor -
  C0J00_RS07945 (C0J00_07950) - 1561922..1562920 (-) 999 WP_104968360.1 sensor histidine kinase -
  C0J00_RS07950 (C0J00_07955) liaF 1562917..1563615 (-) 699 WP_104968361.1 cell wall-active antibiotics response protein LiaF -
  C0J00_RS07955 (C0J00_07960) stkP/pknB 1563780..1565663 (-) 1884 WP_104968362.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  C0J00_RS07960 (C0J00_07965) - 1565663..1566400 (-) 738 WP_104968867.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  C0J00_RS07965 (C0J00_07970) rsmB 1566449..1567771 (-) 1323 WP_104968363.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  C0J00_RS07970 (C0J00_07975) fmt 1567761..1568702 (-) 942 WP_104968364.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68141.21 Da        Isoelectric Point: 4.7670

>NTDB_id=262366 C0J00_RS07955 WP_104968362.1 1563780..1565663(-) (stkP/pknB) [Streptococcus pluranimalium strain TH11417]
MIQIGKLFAGRYRILKSIGRGGMADVYLAHDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLAMEYVNGSDLKKYIQDHAPLSNTETVRIMSEVLSAMQLAHQKGIVHRDLKPQNVLLTKDGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTCHIPFDGDSAVTIALQHFQKPLPSIIFENRNVP
QALENVVIKATAKKLGDRYVSTTDMYQDLGTSLDSRRARESKLVFQDTTDTKTLPKIEPSPVKEAPKAAVASDSVEVPKE
KEASKKDASTPPSSKKSKKPFWQRLFRFFILALVLLLAGFAFFFMSSSNDSATVPDVSGQTIQEAQATLEEAGLTVGAVS
RKESDSVEEGKVISTTPKSGTTQKEGSEVDLLVSKGSKRFVMTDYTGMSYRDAVSDLTENYGLSKNQIVKKEVTNNQYEP
GEIVSQTPEAGEDFNPSGNDKIIFEVATASTVTIPTLVGYSYADAKNALLDLGFKASQIQTDSDQPSSSATVYAQYPYAG
TSVELSSGETVTLYLTTPEPSSTQPSSSSEEIDTDSSNQTSSSSSSSSSNHSTEATGDANSQPETTD

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=262366 C0J00_RS07955 WP_104968362.1 1563780..1565663(-) (stkP/pknB) [Streptococcus pluranimalium strain TH11417]
ATGATCCAAATCGGCAAATTATTTGCTGGGCGTTATCGTATTTTAAAATCTATCGGTCGCGGTGGCATGGCTGATGTTTA
TTTGGCACATGATTTGATTTTGGATAATGAAGAAGTAGCGATTAAGGTGCTTCGAACCAATTATCAAACAGATCAAATTG
CAGTCGCGCGTTTCCAGAGAGAAGCGCGTGCGATGGCTGAATTAAATCATCCTAACATTGTAGCTATCAGAGATATCGGC
GAAGAAGATGGACAACAATTCCTTGCCATGGAATACGTTAATGGTTCAGATTTAAAGAAGTATATTCAAGATCATGCACC
TCTTTCTAATACTGAGACAGTTCGTATCATGAGTGAGGTGTTATCAGCTATGCAGCTGGCTCATCAAAAAGGAATTGTTC
ATCGTGACTTGAAACCACAGAATGTTCTTTTGACAAAAGACGGAGTAGCTAAGGTAACTGATTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTTTGACACAGACAAATTCGATGTTAGGAAGTGTTCATTACTTGTCACCAGAGCAAGCACGAGGCTC
TAAAGCAACGATACAAAGTGATATTTATGCTATGGGTATCATGTTGTTTGAAATGTTGACTTGTCATATCCCATTTGATG
GTGATAGTGCTGTTACGATTGCATTGCAACACTTTCAAAAACCTTTGCCATCGATTATTTTTGAAAATCGAAATGTTCCA
CAAGCTTTGGAGAATGTTGTTATCAAAGCAACTGCTAAAAAGCTCGGAGATCGCTATGTATCAACGACAGATATGTATCA
AGATTTAGGGACATCCCTAGATTCGCGCCGTGCTAGAGAATCAAAGTTAGTTTTTCAAGATACAACAGATACTAAGACAT
TACCTAAAATTGAGCCTTCACCTGTTAAAGAGGCACCTAAAGCAGCAGTTGCTTCGGATAGTGTTGAAGTGCCTAAAGAA
AAGGAAGCTTCTAAAAAAGACGCCTCTACACCGCCGTCATCTAAAAAGTCTAAGAAACCTTTTTGGCAACGTCTATTCCG
ATTTTTCATTTTGGCCCTCGTTTTATTACTAGCCGGTTTTGCATTCTTCTTTATGTCAAGTAGCAATGATAGTGCAACAG
TTCCTGATGTCTCAGGGCAAACAATCCAAGAAGCTCAAGCCACTCTAGAAGAGGCTGGTTTGACTGTAGGAGCTGTTTCT
CGTAAAGAAAGTGACAGTGTTGAGGAAGGAAAGGTCATTTCAACAACACCGAAATCAGGAACCACTCAAAAAGAGGGAAG
CGAAGTTGATTTACTAGTTTCAAAAGGTTCTAAACGCTTTGTTATGACAGATTATACCGGGATGTCATATAGGGATGCTG
TTAGTGATTTGACGGAAAATTATGGTTTGTCTAAAAATCAAATTGTCAAAAAAGAAGTTACAAATAATCAGTATGAACCG
GGAGAAATTGTTAGTCAGACTCCAGAAGCTGGCGAAGATTTTAACCCTTCAGGTAATGATAAGATTATTTTTGAAGTAGC
AACAGCTTCAACAGTAACAATACCAACTTTGGTTGGTTACAGTTATGCAGATGCCAAGAATGCTTTATTAGACCTAGGAT
TTAAAGCTTCTCAGATTCAGACAGATTCAGATCAACCGTCGTCATCGGCAACGGTTTATGCACAATACCCATATGCAGGG
ACGTCTGTTGAACTCTCATCTGGAGAAACGGTAACATTATATCTAACAACTCCTGAACCATCATCGACGCAACCGTCATC
ATCTTCTGAGGAGATAGATACGGATAGTAGTAATCAGACCTCTTCATCAAGTAGTTCTTCTAGTTCCAACCATTCAACGG
AAGCAACAGGTGATGCAAACAGCCAACCAGAAACTACTGACTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(512-576)

PASTA domain (PASTA)

(373-435)

PASTA domain (PASTA)

(441-507)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D633

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

63.14

93.461

0.59
  pknB Streptococcus mutans UA159

62.01

93.62

0.581
  stkP Streptococcus pneumoniae TIGR4

53.299

94.258

0.502
  stkP Streptococcus pneumoniae D39

53.13

94.258

0.501
  stkP Streptococcus pneumoniae R6

53.13

94.258

0.501
  stkP Streptococcus pneumoniae Rx1

52.961

94.258

0.499

Multiple sequence alignment