Detailed information NTG0262357

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: C0J00_RS07180
• Genome accession: NZ_CP025536
• Coordinates: 1416353..1418503 (+)
• Length: 716 a.a.
• NCBI ID: WP_104968236.1
• Uniprot ID: A0A2L0D5E8
• Organism: Streptococcus pluranimalium strain TH11417
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1411353..1423503

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C0J00_RS07155 (C0J00_07160)	traF	1412940..1414127 (-)	1188	WP_104968231.1	conjugal transfer protein TraF	-
C0J00_RS07160 (C0J00_07165)	-	1414682..1414978 (-)	297	WP_104968232.1	bacteriocin immunity protein	-
C0J00_RS07165 (C0J00_07170)	-	1415222..1415596 (-)	375	WP_104968233.1	hypothetical protein	-
C0J00_RS07170 (C0J00_07175)	-	1415628..1415825 (-)	198	WP_104968234.1	Blp family class II bacteriocin	-
C0J00_RS07175 (C0J00_07180)	-	1415834..1416046 (-)	213	WP_104968235.1	Blp family class II bacteriocin	-
C0J00_RS07180 (C0J00_07185)	comA/nlmT	1416353..1418503 (+)	2151	WP_104968236.1	peptide cleavage/export ABC transporter	Regulator
C0J00_RS07185 (C0J00_07190)	-	1418513..1419838 (+)	1326	WP_104968237.1	bacteriocin secretion accessory protein	-
C0J00_RS10450	-	1419987..1420124 (+)	138	WP_158667322.1	bacteriocin	-
C0J00_RS07190 (C0J00_07195)	-	1420205..1421512 (-)	1308	WP_104968238.1	GHKL domain-containing protein	-
C0J00_RS07195 (C0J00_07200)	-	1421509..1422252 (-)	744	WP_104968239.1	LytR/AlgR family response regulator transcription factor	-
C0J00_RS07200 (C0J00_07205)	-	1422701..1422925 (+)	225	WP_158667323.1	hypothetical protein	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 79904.79 Da
• Isoelectric Point: 7.1130

>NTDB_id=262357 C0J00_RS07180 WP_104968236.1 1416353..1418503(+) (comA/nlmT) [Streptococcus pluranimalium strain TH11417]
MSRYKRTFIPQVDARDCGVAALASIAAFYGSRYSLAHLRELAKTNKEGTTALGLVKAAQEIDFETRAIQADASLFEMDDV
PYPFIVHVNKEGKLQHYYVVYQAGKKGLVIGDPDPSVKVTKMSYDTFLSEWTGVALFMGPKPSYKPHKDKKNGLTSFLPL
IFKQKAVISQIVIASLLVTIINIVGSYYLQSILDDYIPNHMLSTLGIISVGLIVTYVIQQVMTFARDYLLTVLSQRLTID
VILSYIKHIFDLPMSFFATRRTGEITSRFTDATAIIDALASTILSLFLDVSIVVIVGGVLLLQNPHLFLLSLVSIPVYLV
IIFAFMKPFERMNNDVMQSNAMVSSAIIEDINGIETIKSLTSEEVRYQKIDREFVDYLDKSFILSKLSTLQSALKQGAQL
ILNVLILWLGSRLVIQGKISVGQLITFNTLLSYFTDPLENIINLQTKLQSAKVANTRLNEVYLVDSEFKDNTFETDATML
NGDIIFDHVSYKYGFGRDTLSDISLTINEKTKVALVGISGSGKTTLAKMIVNFYEPYQGTIRVNGNDLKTLNKKVLRRHI
NYLPQQAYIFDGSILDNLTLGVQEGISQEDIIRACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLLALDKTIIFVAHRLSIAQRAEKILVLDQGKVVEEGSHSDLVRRQGFYYHLFSK

Nucleotide

• Length: 2151 bp

>NTDB_id=262357 C0J00_RS07180 WP_104968236.1 1416353..1418503(+) (comA/nlmT) [Streptococcus pluranimalium strain TH11417]
ATGTCAAGATACAAACGAACCTTTATCCCTCAGGTTGATGCTAGGGATTGTGGGGTGGCAGCTTTGGCTTCTATTGCTGC
TTTTTATGGGTCTAGGTACTCACTCGCTCACTTAAGAGAACTCGCTAAAACCAATAAGGAGGGCACCACCGCTCTTGGAT
TAGTCAAGGCTGCTCAAGAAATCGACTTTGAAACACGAGCCATCCAAGCGGATGCTAGTCTCTTTGAAATGGATGATGTT
CCCTATCCTTTCATCGTACATGTCAATAAGGAAGGAAAACTACAACACTACTATGTTGTCTATCAGGCTGGCAAGAAAGG
GCTAGTCATTGGTGATCCTGATCCTAGTGTCAAAGTCACTAAAATGTCCTACGATACCTTCCTTTCTGAATGGACTGGTG
TTGCCTTATTTATGGGACCTAAACCATCCTACAAGCCCCATAAGGATAAAAAGAATGGCTTGACCAGTTTTCTGCCCCTC
ATTTTTAAGCAGAAAGCTGTTATTAGTCAGATTGTCATTGCTAGCCTCCTTGTGACCATCATTAACATTGTTGGTTCTTA
TTATCTGCAATCTATTTTAGATGATTATATTCCCAATCATATGCTCTCCACGCTTGGGATCATTTCTGTTGGCTTGATTG
TGACTTATGTTATCCAACAAGTGATGACCTTTGCCAGGGATTATCTGCTTACCGTGCTCAGTCAGCGCTTGACCATCGAT
GTTATTTTGTCTTATATCAAGCACATTTTTGACCTTCCCATGTCTTTTTTTGCGACTAGACGTACTGGAGAAATCACGTC
ACGCTTTACAGATGCCACTGCTATCATTGATGCTCTAGCGTCCACTATCCTATCTCTTTTTCTAGACGTCTCAATCGTTG
TCATTGTCGGTGGGGTCTTGTTACTGCAAAACCCTCATCTTTTCTTACTGTCACTCGTTTCTATTCCAGTCTATCTTGTC
ATTATTTTTGCCTTTATGAAACCTTTTGAACGGATGAATAACGATGTGATGCAAAGTAATGCCATGGTCAGTTCAGCCAT
TATTGAGGATATCAACGGGATTGAGACGATTAAATCATTAACCAGTGAGGAAGTGCGTTACCAAAAGATTGACCGTGAGT
TTGTGGATTATCTCGATAAATCTTTCATTTTAAGCAAACTGTCTACTCTTCAGTCCGCTTTGAAGCAAGGCGCTCAACTC
ATTCTCAATGTCCTCATCCTTTGGTTAGGGTCAAGACTTGTGATTCAAGGAAAAATCTCCGTTGGTCAACTCATTACCTT
TAACACCTTGTTAAGCTATTTTACGGATCCTTTAGAAAATATCATCAACCTCCAAACCAAATTACAATCTGCAAAAGTTG
CCAATACCCGCCTCAATGAAGTTTACCTAGTTGATTCTGAATTTAAAGACAACACCTTTGAAACGGATGCTACGATGCTT
AATGGCGATATCATTTTTGATCACGTTTCTTATAAATATGGTTTTGGACGCGATACCTTATCTGATATTTCCCTTACCAT
CAACGAAAAAACAAAAGTTGCTCTGGTGGGCATTAGTGGTTCTGGTAAAACAACTCTCGCTAAAATGATTGTCAATTTTT
ATGAGCCTTATCAGGGAACGATTCGAGTGAATGGTAACGATCTTAAAACACTCAATAAGAAAGTGCTACGCCGCCATATT
AATTATCTACCCCAGCAGGCTTATATTTTTGATGGCTCCATCCTTGACAACCTGACCCTAGGAGTTCAAGAAGGGATTAG
CCAAGAAGACATTATAAGAGCTTGTGAGATTGCCGAAATTCGTCAGGATATTGAACAAATGCCTATGGGCTATCAAACGG
AGTTATCAGATGGCGCAGGCTTATCCGGTGGACAGAAACAACGCATTGCCCTAGCCCGCGCCTTGCTCACAAAAGCACCA
GTTCTCATTCTTGACGAAGCGACAAGTGGCTTGGATGTTCTCACAGAGAAAAAAGTCATTGACAACCTCTTAGCTCTTGA
TAAAACTATTATCTTTGTGGCGCACCGTCTCAGCATTGCTCAACGAGCTGAGAAAATCCTTGTCTTAGACCAAGGCAAAG
TGGTAGAAGAAGGCTCCCATAGCGATTTGGTGAGACGCCAAGGCTTTTATTATCATTTATTTAGTAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (171-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: A0A2L0D5E8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.448	99.721	0.703
comA	Streptococcus mitis NCTC 12261	67.465	99.162	0.669
comA	Streptococcus mitis SK321	66.901	99.162	0.663
comA	Streptococcus pneumoniae Rx1	66.901	99.162	0.663
comA	Streptococcus pneumoniae D39	66.901	99.162	0.663
comA	Streptococcus pneumoniae R6	66.901	99.162	0.663
comA	Streptococcus pneumoniae TIGR4	66.62	99.162	0.661
comA	Streptococcus gordonii str. Challis substr. CH1	65.126	99.721	0.649