Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   C0J00_RS07090 Genome accession   NZ_CP025536
Coordinates   1402918..1403634 (-) Length   238 a.a.
NCBI ID   WP_104968219.1    Uniprot ID   A0A2L0D503
Organism   Streptococcus pluranimalium strain TH11417     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1397918..1408634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS07070 (C0J00_07075) pstA 1398535..1399350 (-) 816 WP_104968215.1 phosphate ABC transporter permease PstA -
  C0J00_RS07075 (C0J00_07080) pstC 1399343..1400203 (-) 861 WP_104968216.1 phosphate ABC transporter permease subunit PstC -
  C0J00_RS07080 (C0J00_07085) - 1400482..1401363 (-) 882 WP_104968217.1 substrate-binding domain-containing protein -
  C0J00_RS07085 (C0J00_07090) pnpS 1401578..1402918 (-) 1341 WP_104968218.1 two-component system histidine kinase PnpS -
  C0J00_RS07090 (C0J00_07095) vicR 1402918..1403634 (-) 717 WP_104968219.1 response regulator transcription factor Regulator
  C0J00_RS07095 (C0J00_07100) - 1403771..1404619 (-) 849 WP_104968220.1 aldo/keto reductase -
  C0J00_RS07100 (C0J00_07105) - 1404961..1405476 (+) 516 WP_104968221.1 RNA polymerase sigma factor -
  C0J00_RS07105 (C0J00_07110) - 1405454..1406425 (+) 972 WP_104968222.1 anti sigma factor C-terminal domain-containing protein -
  C0J00_RS07110 (C0J00_07115) - 1407005..1407202 (+) 198 WP_104968223.1 hypothetical protein -
  C0J00_RS07115 (C0J00_07120) - 1407338..1408384 (-) 1047 WP_104968224.1 LLM class flavin-dependent oxidoreductase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27528.83 Da        Isoelectric Point: 5.4806

>NTDB_id=262356 C0J00_RS07090 WP_104968219.1 1402918..1403634(-) (vicR) [Streptococcus pluranimalium strain TH11417]
MQKRVLIVDDEPHILTLVSYHLAKEGFEVTTVEDGRSALELGQGQPFDFIVLDIMLPQLDGVEVCKRLRKAGIETPILML
SAKGEEFDKVLALELGADDYMTKPFSPRELLARIKAILRRTEKNQLSELLQEEDQSDTKFQVADLTVYLERHQIYKADRE
ISLTPKEFELLVYLLKHPRMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPAIIKTVRGYGYKFEGDK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=262356 C0J00_RS07090 WP_104968219.1 1402918..1403634(-) (vicR) [Streptococcus pluranimalium strain TH11417]
ATGCAAAAGCGTGTTTTAATCGTGGATGATGAGCCACATATTCTCACTTTGGTTTCCTACCATTTAGCTAAGGAAGGTTT
TGAGGTAACGACTGTCGAAGATGGTCGGTCTGCCCTAGAATTGGGACAAGGTCAGCCCTTTGATTTTATTGTTTTAGATA
TCATGTTGCCACAACTTGATGGTGTTGAAGTTTGTAAAAGACTGCGAAAAGCCGGTATCGAAACCCCTATCCTCATGCTG
TCAGCTAAGGGAGAGGAATTTGATAAGGTTTTAGCTCTGGAATTAGGGGCGGATGACTACATGACCAAGCCCTTTAGTCC
GCGGGAACTTCTGGCTAGGATCAAGGCAATCCTGCGTCGGACTGAGAAAAATCAACTGTCAGAATTGCTCCAAGAAGAAG
ACCAGTCTGATACGAAATTTCAAGTTGCAGACTTAACGGTCTATTTGGAGCGTCATCAGATTTACAAGGCAGATCGAGAG
ATTAGCTTGACGCCTAAAGAGTTTGAACTCTTGGTTTATCTTTTGAAGCATCCTCGTATGACGCTGACCAGAGAACGCCT
GTTGGAGCGAATTTGGGGCTATGATTTTGGGCAGGAGACCCGTTTAGTGGATGTGCATATCGGTAAGTTACGTGAAAAAA
TCGAGGATAATCCCAAGGCACCTGCCATTATCAAAACAGTCAGAGGTTACGGCTACAAGTTTGAAGGAGACAAGTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D503

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

50.435

96.639

0.487
  micA Streptococcus pneumoniae Cp1015

50

96.639

0.483
  covR Streptococcus salivarius strain HSISS4

42.241

97.479

0.412
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.126

97.059

0.399
  scnR Streptococcus mutans UA159

37.021

98.739

0.366

Multiple sequence alignment