Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   C0J00_RS05305 Genome accession   NZ_CP025536
Coordinates   1029030..1029701 (-) Length   223 a.a.
NCBI ID   WP_104967889.1    Uniprot ID   A0A2L0D3Z7
Organism   Streptococcus pluranimalium strain TH11417     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1024030..1034701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS05280 (C0J00_05285) - 1024341..1024730 (-) 390 WP_104967884.1 cytidine deaminase -
  C0J00_RS05285 (C0J00_05290) - 1025323..1025910 (-) 588 WP_104967885.1 class I SAM-dependent methyltransferase -
  C0J00_RS05290 (C0J00_05295) coaA 1026037..1026957 (+) 921 WP_104967886.1 type I pantothenate kinase -
  C0J00_RS05295 (C0J00_05300) rpsT 1027010..1027258 (+) 249 WP_104967887.1 30S ribosomal protein S20 -
  C0J00_RS05300 (C0J00_05305) ciaH 1027733..1029037 (-) 1305 WP_104967888.1 sensor histidine kinase Regulator
  C0J00_RS05305 (C0J00_05310) ciaR 1029030..1029701 (-) 672 WP_104967889.1 response regulator transcription factor Regulator
  C0J00_RS05310 (C0J00_05315) - 1029947..1032481 (-) 2535 WP_104967890.1 M1 family metallopeptidase -
  C0J00_RS05315 (C0J00_05320) phoU 1032603..1033256 (-) 654 WP_104967891.1 phosphate signaling complex protein PhoU -
  C0J00_RS05320 (C0J00_05325) pstB 1033282..1034040 (-) 759 WP_104967892.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25377.22 Da        Isoelectric Point: 4.4478

>NTDB_id=262351 C0J00_RS05305 WP_104967889.1 1029030..1029701(-) (ciaR) [Streptococcus pluranimalium strain TH11417]
MIKLLLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLTDHTIVYGNISVDTTINRVTVDGKEVEFLGKEFELLMY
FLQNQNVILPKTQIFDRLWGFDSDTTLSVVEVYVSKIRKKLKGTSFADHLQTLRSVGYILKDA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=262351 C0J00_RS05305 WP_104967889.1 1029030..1029701(-) (ciaR) [Streptococcus pluranimalium strain TH11417]
ATGATAAAATTACTCTTGGTTGAAGATGATTTGAGTTTGTCCAATTCTGTATTTGATTTTCTGGATGATTTTGCAGATGT
GATGCAGGTCTTTGATGGGGAAGAAGGATTGTATGAAGCTGAATCTGGCGTTTATGATCTTATTTTATTAGATCTTATGC
TTCCAGAAAAAAATGGTTTTCAAGTGCTAAAAGAGCTTCGAGAAAAAGGGATAACAACGCCTGTTTTAATTATGACAGCA
AAGGAAGGGTTGGATGATAAGGGACATGGTTTTGAGTTAGGAGCAGATGATTATTTAACTAAGCCATTTTATCTAGAAGA
ATTAAAAATGAGAATCCAAGCCTTACTTAAACGTTCTGGAAAGCTGACCGATCATACCATCGTATACGGTAATATTAGCG
TTGACACGACAATTAATCGTGTTACAGTAGATGGCAAAGAAGTAGAATTTTTAGGTAAAGAATTTGAATTGTTAATGTAC
TTTCTACAAAACCAAAATGTTATTTTACCTAAAACACAGATTTTTGATCGTTTATGGGGATTTGATAGCGATACAACGCT
TTCGGTTGTTGAAGTTTATGTGTCAAAAATCCGTAAAAAACTTAAAGGAACGAGTTTTGCAGATCATTTACAGACTTTAA
GAAGTGTTGGTTATATTTTAAAAGATGCATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D3Z7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

87.444

100

0.874
  ciaR Streptococcus pneumoniae Rx1

86.547

100

0.865
  ciaR Streptococcus pneumoniae D39

86.547

100

0.865
  ciaR Streptococcus pneumoniae R6

86.547

100

0.865
  ciaR Streptococcus pneumoniae TIGR4

86.547

100

0.865
  covR Lactococcus lactis subsp. lactis strain DGCC12653

35.841

100

0.363

Multiple sequence alignment