Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   C0J00_RS05300 Genome accession   NZ_CP025536
Coordinates   1027733..1029037 (-) Length   434 a.a.
NCBI ID   WP_104967888.1    Uniprot ID   A0A2L0D4Q8
Organism   Streptococcus pluranimalium strain TH11417     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1022733..1034037
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS05275 (C0J00_05280) - 1023201..1024250 (-) 1050 WP_104967883.1 BMP family lipoprotein -
  C0J00_RS05280 (C0J00_05285) - 1024341..1024730 (-) 390 WP_104967884.1 cytidine deaminase -
  C0J00_RS05285 (C0J00_05290) - 1025323..1025910 (-) 588 WP_104967885.1 class I SAM-dependent methyltransferase -
  C0J00_RS05290 (C0J00_05295) coaA 1026037..1026957 (+) 921 WP_104967886.1 type I pantothenate kinase -
  C0J00_RS05295 (C0J00_05300) rpsT 1027010..1027258 (+) 249 WP_104967887.1 30S ribosomal protein S20 -
  C0J00_RS05300 (C0J00_05305) ciaH 1027733..1029037 (-) 1305 WP_104967888.1 sensor histidine kinase Regulator
  C0J00_RS05305 (C0J00_05310) ciaR 1029030..1029701 (-) 672 WP_104967889.1 response regulator transcription factor Regulator
  C0J00_RS05310 (C0J00_05315) - 1029947..1032481 (-) 2535 WP_104967890.1 M1 family metallopeptidase -
  C0J00_RS05315 (C0J00_05320) phoU 1032603..1033256 (-) 654 WP_104967891.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 49885.50 Da        Isoelectric Point: 9.5266

>NTDB_id=262350 C0J00_RS05300 WP_104967888.1 1027733..1029037(-) (ciaH) [Streptococcus pluranimalium strain TH11417]
MHKYIQKKIHSDNFKPFIHFMMVFTAIFFVMTIIILQIMRLGLYSSTDNSLKRARYSAASYIAMTMARNYSWSSDGDGFG
ITIDPSKFKHNDDLAVLDIIVFDRFGEVINTVDAYSEFSSIKLNKKQLNRIVKETHINTYGHAENYRSVTLEVTDLAYPQ
VKYISFLASTRQLDEAFDRYVNVIISIMIIFWLISVITSVYLAKWSRKPIIASYEKQKSFVENASHELRTPLAVLQNRLE
TLFRKPNDTILEHSESIAASLDEVRNMRMLTTNLLNLARRDDGIDPNIEDISPTFFDDVFKNYQLIAQENDKELMVMNHL
KRPIKSDKTLIKQLMTILVDNALKYTKKQGIISISVETKGRRLWLRVSDNGLGISDDDKSKIFDRFYRVDKARTRQSGGF
GLGLSLAKQIVDTLGGEITVKDNTPQGTIFDVFL

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=262350 C0J00_RS05300 WP_104967888.1 1027733..1029037(-) (ciaH) [Streptococcus pluranimalium strain TH11417]
ATGCATAAATACATACAAAAAAAAATTCATTCTGATAATTTCAAGCCCTTTATCCATTTTATGATGGTATTCACTGCTAT
TTTCTTTGTGATGACGATTATTATTTTGCAGATTATGAGACTTGGTCTCTACTCTTCAACGGATAATAGTCTGAAAAGAG
CTAGGTACTCTGCGGCTAGTTATATTGCAATGACTATGGCTAGGAATTACTCTTGGAGCTCAGATGGAGATGGTTTCGGT
ATTACAATCGATCCTAGTAAGTTTAAACACAATGATGATCTGGCTGTTTTAGATATTATTGTATTTGATAGATTTGGAGA
GGTTATTAATACGGTTGATGCTTATTCTGAATTTTCAAGTATTAAGCTTAATAAAAAACAGCTCAATAGAATTGTTAAAG
AGACTCACATCAACACTTATGGACATGCTGAAAATTATCGCAGTGTCACGCTTGAAGTTACCGATTTAGCTTATCCTCAA
GTAAAATATATTAGTTTTCTAGCGAGTACGAGACAATTGGATGAGGCATTTGACCGCTATGTTAATGTTATTATAAGCAT
TATGATTATCTTTTGGTTGATATCAGTTATCACTAGTGTTTATCTAGCCAAGTGGAGTCGTAAACCAATCATTGCTAGTT
ATGAAAAACAAAAGAGCTTTGTTGAAAATGCCAGCCATGAATTAAGAACGCCCCTGGCTGTACTCCAAAATCGCTTAGAA
ACCTTGTTTAGAAAACCTAATGATACTATTCTTGAACATAGCGAGAGTATTGCAGCAAGTCTTGATGAAGTTAGAAATAT
GAGAATGTTAACGACAAATCTCTTAAACTTAGCTCGTCGTGATGATGGTATTGACCCGAACATAGAAGATATTTCACCAA
CATTTTTTGATGATGTCTTTAAAAATTACCAATTAATTGCTCAAGAGAATGACAAGGAGTTAATGGTAATGAATCATTTG
AAACGACCTATTAAATCAGATAAAACGCTCATAAAACAGTTGATGACTATTTTAGTTGATAACGCCTTGAAATATACAAA
GAAGCAAGGGATTATTAGTATTTCTGTTGAAACCAAAGGGCGCCGTTTGTGGTTGAGAGTATCTGATAATGGTCTAGGTA
TTTCAGATGATGATAAATCGAAAATCTTTGATCGATTTTACCGTGTTGATAAAGCAAGAACGAGACAATCTGGTGGATTT
GGTCTAGGTTTATCTCTTGCCAAGCAGATTGTAGATACTTTAGGTGGAGAGATAACAGTAAAAGATAATACACCTCAAGG
AACTATTTTTGATGTTTTCTTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-283)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D4Q8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.028

99.539

0.588
  ciaH Streptococcus pneumoniae Rx1

48.174

100

0.486
  ciaH Streptococcus pneumoniae D39

48.174

100

0.486
  ciaH Streptococcus pneumoniae R6

48.174

100

0.486
  ciaH Streptococcus pneumoniae TIGR4

48.174

100

0.486

Multiple sequence alignment