Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   C0J00_RS01405 Genome accession   NZ_CP025536
Coordinates   269172..269930 (+) Length   252 a.a.
NCBI ID   WP_104967219.1    Uniprot ID   A0A2L0D226
Organism   Streptococcus pluranimalium strain TH11417     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 264172..274930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS01380 (C0J00_01380) - 265441..265944 (-) 504 WP_104967214.1 phosphatidylglycerophosphatase A -
  C0J00_RS01385 (C0J00_01385) - 266151..267467 (+) 1317 WP_104967215.1 FAD-containing oxidoreductase -
  C0J00_RS01390 (C0J00_01390) - 267477..267833 (+) 357 WP_104967216.1 DUF2200 domain-containing protein -
  C0J00_RS01395 (C0J00_01395) - 268038..268595 (+) 558 WP_158667298.1 DUF1697 domain-containing protein -
  C0J00_RS01400 (C0J00_01400) - 268596..269093 (+) 498 WP_104967218.1 phosphatase PAP2 family protein -
  C0J00_RS01405 (C0J00_01405) mecA 269172..269930 (+) 759 WP_104967219.1 adaptor protein MecA Regulator
  C0J00_RS01410 (C0J00_01410) - 269931..271088 (+) 1158 WP_104967220.1 glycosyltransferase family 4 protein -
  C0J00_RS01415 (C0J00_01415) sufC 271196..271966 (+) 771 WP_104967221.1 Fe-S cluster assembly ATPase SufC -
  C0J00_RS01420 (C0J00_01420) - 271979..272494 (+) 516 WP_104967222.1 GNAT family N-acetyltransferase -
  C0J00_RS01425 (C0J00_01425) sufD 272498..273760 (+) 1263 WP_104967223.1 Fe-S cluster assembly protein SufD -

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 28915.52 Da        Isoelectric Point: 4.2427

>NTDB_id=262333 C0J00_RS01405 WP_104967219.1 269172..269930(+) (mecA) [Streptococcus pluranimalium strain TH11417]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKNSGMLSFRVTPKKDRLDVFVTKSEI
DKDLNFDDLAALGDVSQMSPDEFFKTLEKSMLEKGDTEAHEKLKQMEEIVESAMTEQTSEADSVHEPNEDNAEQDSYTHY
VLQFPMLKDAVAFSKAIDFDIEASELYKFNGSYYITILVSLENKPAYYADLVHARLLEHSRGGQKTRAYLQEHGVRLLEG
YAVADLEGIKVV

Nucleotide


Download         Length: 759 bp        

>NTDB_id=262333 C0J00_RS01405 WP_104967219.1 269172..269930(+) (mecA) [Streptococcus pluranimalium strain TH11417]
ATGGAAATGAAACAAATTAGCGAAACAACGCTAAAAATAACGATTAGTATGGAAGATTTGGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTTATTCCTCAAGAAAAAACAGAAGAATTTTTTTATTCCGTGATGGACGAACTTGACTTACCAGATAACT
TCAAAAATAGTGGCATGTTGAGTTTTCGAGTGACACCTAAGAAAGATCGATTAGATGTTTTTGTAACCAAGTCTGAAATT
GATAAGGATTTAAACTTTGATGATTTAGCAGCCTTGGGGGATGTCTCTCAAATGTCTCCGGATGAATTCTTTAAGACATT
AGAAAAATCGATGTTGGAGAAGGGTGATACAGAAGCTCACGAGAAGTTAAAACAAATGGAAGAAATCGTGGAATCTGCGA
TGACAGAGCAAACATCAGAAGCAGACTCAGTACATGAACCTAATGAAGATAATGCTGAACAAGACAGTTATACGCACTAT
GTGTTACAGTTTCCCATGCTGAAAGATGCTGTTGCTTTTTCAAAAGCGATTGACTTTGATATAGAAGCATCAGAACTGTA
TAAATTCAACGGCAGTTACTATATTACTATCTTGGTCAGTCTAGAAAATAAGCCCGCTTATTATGCCGACTTGGTTCACG
CTCGCTTGTTGGAGCACAGTCGTGGTGGTCAAAAAACAAGAGCCTATCTGCAAGAGCATGGCGTCCGTTTGCTTGAAGGC
TATGCGGTGGCTGATTTAGAAGGTATCAAGGTGGTCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D226

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

59.839

98.81

0.591
  mecA Streptococcus thermophilus LMD-9

55.512

100

0.56
  mecA Streptococcus thermophilus LMG 18311

54.724

100

0.552
  mecA Streptococcus pneumoniae Rx1

49.603

100

0.496
  mecA Streptococcus pneumoniae D39

49.603

100

0.496
  mecA Streptococcus pneumoniae R6

49.603

100

0.496
  mecA Streptococcus pneumoniae TIGR4

49.603

100

0.496

Multiple sequence alignment