Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CYK55_RS01555 Genome accession   NZ_CP025473
Coordinates   250687..251991 (-) Length   434 a.a.
NCBI ID   WP_034689954.1    Uniprot ID   -
Organism   Enterococcus mundtii strain Pe161     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 245687..256991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CYK55_RS01525 (CYK55_01540) - 246113..247072 (-) 960 WP_034689143.1 glycosyltransferase family 2 protein -
  CYK55_RS01530 (CYK55_01545) - 247211..247561 (-) 351 WP_034689140.1 PepSY domain-containing protein -
  CYK55_RS01535 (CYK55_01550) pepA 247763..248842 (+) 1080 WP_034689137.1 glutamyl aminopeptidase -
  CYK55_RS01540 (CYK55_01555) - 248966..249286 (+) 321 WP_034689135.1 thioredoxin family protein -
  CYK55_RS01545 (CYK55_01560) - 249308..249763 (+) 456 WP_034689132.1 universal stress protein -
  CYK55_RS01550 (CYK55_01570) ytpR 250034..250639 (+) 606 WP_034689956.1 YtpR family tRNA-binding protein -
  CYK55_RS01555 (CYK55_01575) htrA 250687..251991 (-) 1305 WP_034689954.1 trypsin-like peptidase domain-containing protein Regulator
  CYK55_RS01560 (CYK55_01580) rlmH 252420..252899 (+) 480 WP_034689953.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CYK55_RS01565 (CYK55_01585) - 253102..254310 (+) 1209 WP_241234784.1 PD-(D/E)XK nuclease family protein -
  CYK55_RS13925 - 254479..254601 (+) 123 WP_277600565.1 hypothetical protein -
  CYK55_RS01570 (CYK55_01590) - 254658..255065 (+) 408 WP_126133827.1 hypothetical protein -
  CYK55_RS01575 (CYK55_01595) - 255376..255606 (+) 231 WP_010728023.1 hypothetical protein -
  CYK55_RS01580 (CYK55_01600) - 255927..256235 (+) 309 WP_126134422.1 DUF960 domain-containing protein -
  CYK55_RS01585 (CYK55_01605) - 256262..256561 (+) 300 WP_126133828.1 4'-phosphopantetheinyl transferase -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 45108.03 Da        Isoelectric Point: 4.4838

>NTDB_id=261827 CYK55_RS01555 WP_034689954.1 250687..251991(-) (htrA) [Enterococcus mundtii strain Pe161]
MDRRDVTPKMKKRKSNGIWRKLGLGVVGGVIGGLLTFGIFYAATGGGNSVTTSSSSGTQNASGETVVENVKVNVDSDITS
AVDKVQGAVVSVINLQKQSSSSDPFGSLFGQQQESSGEDGELQAYSEGSGVIYKKEGGSAYIVTNNHVVDGQQGLEVLLK
DGTKVKAELVGTDAYTDLAVLKISADKVDTVASFGDSASLKVGEPAIAIGSPLGSQYANSVTSGIISSLNRQVTSTNESN
ETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSDSSSVSVEGMGFAIPSNDVVNIINQLERDGKVTRPALG
ITMTDLSAVSTQQQEQILKLPSSVTNGVIIRSVQPATPAEKAGLEQYDVITKIDDTEVSSGVELQSVLYGKKVGDTVKIT
YYRGEEEKTVDIKLTIDNTALNQGNSNSSNGSNN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=261827 CYK55_RS01555 WP_034689954.1 250687..251991(-) (htrA) [Enterococcus mundtii strain Pe161]
ATGGACAGAAGAGATGTGACACCAAAAATGAAAAAAAGAAAATCTAATGGCATTTGGCGAAAGCTAGGTCTTGGCGTAGT
TGGTGGCGTGATTGGCGGATTACTGACTTTCGGTATTTTTTATGCAGCAACTGGAGGTGGTAACTCAGTAACGACTTCTT
CTAGCAGTGGGACACAAAATGCATCAGGCGAAACAGTTGTCGAAAATGTAAAAGTCAATGTAGATTCAGATATCACTTCT
GCAGTAGATAAAGTACAAGGAGCAGTTGTTTCTGTTATCAACCTACAAAAACAAAGTTCATCATCTGACCCGTTTGGTTC
ATTATTTGGCCAACAACAAGAAAGTAGTGGCGAAGATGGCGAATTGCAAGCTTACAGTGAAGGTAGCGGTGTGATCTATA
AAAAAGAGGGCGGTTCCGCTTATATCGTGACGAATAATCACGTGGTCGATGGACAACAAGGGTTAGAAGTTTTATTAAAA
GATGGAACAAAAGTGAAAGCAGAATTAGTCGGTACAGATGCTTACACTGATTTAGCTGTATTGAAAATCAGTGCTGACAA
AGTCGACACTGTTGCTTCATTTGGCGATTCTGCTTCATTGAAAGTCGGCGAACCTGCAATTGCGATTGGTTCTCCTCTAG
GTTCTCAATACGCGAATTCCGTAACATCAGGGATCATTTCTTCCTTGAATCGCCAAGTGACAAGTACCAATGAATCTAAT
GAAACGGTCAATATCAACGCGATCCAAACAGATGCAGCGATCAACCCGGGGAACTCTGGTGGTCCACTAGTTAATATCGA
AGGACAAGTCATTGGTATCAATTCAAGTAAAATTGCATCGACTTCTGATTCTTCAAGTGTAAGTGTTGAAGGAATGGGCT
TTGCGATTCCAAGTAATGATGTCGTAAATATCATCAATCAACTTGAAAGAGATGGAAAAGTAACACGCCCTGCACTGGGT
ATCACAATGACCGATCTTTCAGCCGTTTCTACACAACAACAGGAACAGATCTTAAAATTACCATCTTCTGTAACAAATGG
CGTGATCATTCGTTCTGTTCAACCAGCAACGCCTGCGGAAAAAGCTGGCTTAGAACAATATGATGTCATCACAAAAATCG
ATGATACAGAAGTCTCATCTGGTGTTGAATTACAGTCTGTGCTTTATGGTAAAAAAGTTGGTGACACTGTGAAGATCACT
TATTACCGTGGCGAAGAAGAAAAAACTGTAGATATCAAATTGACAATTGATAATACTGCATTAAACCAAGGAAATTCAAA
TAGTTCCAATGGCTCAAATAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(128-273)

Peptidase family M50 (Peptidase_M50)

(13-416)

PDZ domain (PDZ_2)

(317-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.01

90.092

0.505
  htrA Streptococcus gordonii str. Challis substr. CH1

51.605

93.318

0.482
  htrA Streptococcus mitis NCTC 12261

52.525

91.244

0.479
  htrA Streptococcus pneumoniae Rx1

58.333

77.419

0.452
  htrA Streptococcus pneumoniae D39

58.333

77.419

0.452
  htrA Streptococcus pneumoniae R6

58.333

77.419

0.452
  htrA Streptococcus pneumoniae TIGR4

58.333

77.419

0.452

Multiple sequence alignment