Detailed information NTG0260960

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: CR921_RS09755
• Genome accession: NZ_CP025399
• Coordinates: 1855171..1856406 (+)
• Length: 411 a.a.
• NCBI ID: WP_011681767.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain GABA
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1850171..1861406

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR921_RS09725	-	1850638..1853244 (+)	2607	WP_024704279.1	YfhO family protein	-
CR921_RS09745	-	1853788..1854471 (-)	684	WP_011226711.1	YoaK family protein	-
CR921_RS09750	rlmH	1854487..1854966 (-)	480	WP_011681766.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
CR921_RS09755	htrA	1855171..1856406 (+)	1236	WP_011681767.1	S1C family serine protease	Regulator
CR921_RS09760	spo0J	1856472..1857239 (+)	768	WP_011681768.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42797.07 Da
• Isoelectric Point: 4.7061

>NTDB_id=260960 CR921_RS09755 WP_011681767.1 1855171..1856406(+) (htrA) [Streptococcus thermophilus strain GABA]
MKKINWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGAKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=260960 CR921_RS09755 WP_011681767.1 1855171..1856406(+) (htrA) [Streptococcus thermophilus strain GABA]
ATGAAAAAAATTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGCAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGCCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTCGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATTGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (46-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.538	98.054	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus mitis NCTC 12261	53.808	99.027	0.533
htrA	Streptococcus pneumoniae TIGR4	53.563	99.027	0.53
htrA	Streptococcus pneumoniae D39	53.563	99.027	0.53
htrA	Streptococcus pneumoniae Rx1	53.563	99.027	0.53
htrA	Streptococcus pneumoniae R6	53.563	99.027	0.53