Detailed information NTG0026014

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: SPD_RS06190
• Genome accession: NC_008533
• Coordinates: 1189029..1189670 (-)
• Length: 213 a.a.
• NCBI ID: WP_000151458.1
• Uniprot ID: Q8DPF9
• Organism: Streptococcus pneumoniae D39
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1184029..1194670

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPD_RS06155 (SPD_1154)	-	1184142..1184384 (+)	243	WP_000710764.1	type B 50S ribosomal protein L31	-
SPD_RS06160 (SPD_1155)	-	1184441..1185019 (-)	579	WP_000252103.1	hypothetical protein	-
SPD_RS06165 (SPD_1156)	efeB	1184994..1186007 (-)	1014	Protein_1169	iron uptake transporter deferrochelatase/peroxidase subunit	-
SPD_RS06170	-	1185977..1186468 (-)	492	Protein_1170	winged helix-turn-helix domain-containing protein	-
SPD_RS06175 (SPD_1158)	gdhA	1187004..1188350 (+)	1347	WP_000199534.1	NADP-specific glutamate dehydrogenase	-
SPD_RS11365 (SPD_1159)	-	1188846..1189016 (-)	171	WP_000711943.1	hypothetical protein	-
SPD_RS06190 (SPD_1160)	comA	1189029..1189670 (-)	642	WP_000151458.1	ATP-binding cassette domain-containing protein	Regulator
SPD_RS12020	-	1189795..1189981 (-)	187	Protein_1174	hypothetical protein	-
SPD_RS06200 (SPD_1161)	-	1190044..1190520 (+)	477	Protein_1175	transposase	-
SPD_RS06205 (SPD_1162)	-	1190670..1190864 (-)	195	Protein_1176	ROK family protein	-
SPD_RS06210 (SPD_1163)	-	1190891..1191808 (-)	918	Protein_1177	dihydrodipicolinate synthase family protein	-
SPD_RS06215 (SPD_1164)	-	1191840..1192247 (-)	408	WP_000216067.1	cytidine deaminase	-
SPD_RS06220 (SPD_1165)	-	1192535..1193023 (-)	489	WP_000872894.1	phosphatidylglycerophosphatase A family protein	-
SPD_RS06225 (SPD_1166)	-	1193028..1194437 (-)	1410	WP_000773464.1	hypothetical protein	-

Sequence

Protein

• Length: 213 a.a.
• Molecular weight: 23486.26 Da
• Isoelectric Point: 9.2387

>NTDB_id=26014 SPD_RS06190 WP_000151458.1 1189029..1189670(-) (comA) [Streptococcus pneumoniae D39]
MTIEPGQRIALVGQSGSGKSTLSKIPSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEV
TSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK

Nucleotide

• Length: 642 bp

>NTDB_id=26014 SPD_RS06190 WP_000151458.1 1189029..1189670(-) (comA) [Streptococcus pneumoniae D39]
TTGACTATTGAGCCAGGACAGAGAATTGCACTAGTCGGTCAATCGGGGTCAGGAAAAAGTACGTTATCAAAAATACCATC
AGGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTC
AAAATTTAGGAGTAGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAACATAACTTTAAAGCACGAAGTT
ACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATAC
TATCATCTCAGAGATGGGTTCAAATATTTCAGGTGGTCAAAGACAACGGATAGCACTGGCACGTGCATTAATAAATAATC
CTAGTATTGTAATTTTAGATGAAGCAACTAGTGCTTTAGACACTATTAATGAGGAAAGAATAACAAAGTATATAAAAAGT
CAGGGCTGTACTCAAATAATTGTAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTGTTGTAATGAAAGGTGG
TAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGAGAGTACTACAGCTTATATACAAAAAGGAAAT
GA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (1-144)

3D structure

• AlphaFold DB: Q8DPF9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	43.81	98.592	0.432
comA	Streptococcus mitis SK321	43.333	98.592	0.427
comA	Streptococcus gordonii str. Challis substr. CH1	42.453	99.531	0.423
comA/nlmT	Streptococcus mutans UA159	42.453	99.531	0.423
comA	Streptococcus pneumoniae R6	42.381	98.592	0.418
comA	Streptococcus pneumoniae Rx1	42.381	98.592	0.418
comA	Streptococcus pneumoniae D39	42.381	98.592	0.418
comA	Streptococcus pneumoniae TIGR4	41.429	98.592	0.408
rcrQ	Streptococcus mutans UA159	36.62	100	0.366