Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   CXP32_RS08650 Genome accession   NZ_CP025256
Coordinates   1634703..1636466 (-) Length   587 a.a.
NCBI ID   WP_101258909.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Xen35     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1629703..1641466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXP32_RS08620 (CXP32_08620) - 1629801..1631075 (-) 1275 WP_000704390.1 hydroxymethylglutaryl-CoA reductase, degradative -
  CXP32_RS08625 (CXP32_08625) - 1631075..1632247 (-) 1173 WP_000151960.1 hydroxymethylglutaryl-CoA synthase -
  CXP32_RS08630 (CXP32_08630) - 1632378..1632626 (-) 249 WP_001818278.1 hypothetical protein -
  CXP32_RS08635 (CXP32_08635) - 1632694..1633317 (-) 624 Protein_1625 transposase -
  CXP32_RS08640 (CXP32_08640) - 1633379..1633828 (-) 450 WP_000176924.1 threonine/serine exporter family protein -
  CXP32_RS08645 (CXP32_08645) - 1633830..1634588 (-) 759 WP_000392877.1 threonine/serine exporter ThrE family protein -
  CXP32_RS08650 (CXP32_08650) stkP 1634703..1636466 (-) 1764 WP_101258909.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  CXP32_RS08655 (CXP32_08655) - 1636463..1637203 (-) 741 WP_101258910.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  CXP32_RS08660 (CXP32_08660) rsmB 1637218..1638531 (-) 1314 WP_001814363.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CXP32_RS08665 (CXP32_08665) fmt 1638524..1639459 (-) 936 WP_000163693.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 587 a.a.        Molecular weight: 64471.96 Da        Isoelectric Point: 9.2811

>NTDB_id=259472 CXP32_RS08650 WP_101258909.1 1634703..1636466(-) (stkP) [Streptococcus pneumoniae strain Xen35]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAEGMVVEQSP
RAGEKVDLNKTRVKISIYKPKTTSATP

Nucleotide


Download         Length: 1764 bp        

>NTDB_id=259472 CXP32_RS08650 WP_101258909.1 1634703..1636466(-) (stkP) [Streptococcus pneumoniae strain Xen35]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGTATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGC
GAGGAAGACGGTCAACAGTACCTAGCTATGGAGTATGTGGCTGGACTGGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCAGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTCTTGACACCAGATGGGACTGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
GAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTACCGCTCGGTTTCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAAACAGAACACAAATCAATCAAA
AACCCAAGCCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGCAACGCTCAAAAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGCAAGCAATCTTTCCAAATTAGTAATTATGTCGGTCGGAAATCCTCTGATGTCATTGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCGAATGAGAGTGAGGCTGGAACGGTC
CTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTCTTGACAGTAGCTAAAAAAGT
TACAAGTGTTGCCATGCCGAGTTACATTGGTTCTAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTA
AGGAAGCTAATATAGAAGTTGTAGAAGTGACGACAGCGCCTGCAGGTAGTGCAGAAGGCATGGTTGTTGAACAAAGTCCT
AGAGCAGGTGAAAAGGTAGACCTCAATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCC
TTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(371-432)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(510-579)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

89.171

100

0.898
  stkP Streptococcus pneumoniae D39

88.832

100

0.894
  stkP Streptococcus pneumoniae R6

88.832

100

0.894
  stkP Streptococcus pneumoniae Rx1

88.663

100

0.893
  stkP/pknB Streptococcus salivarius strain HSISS4

52.641

100

0.526
  pknB Streptococcus mutans UA159

53.553

98.296

0.526

Multiple sequence alignment