Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CXM95_RS12680 Genome accession   NZ_CP025223
Coordinates   2639257..2640561 (+) Length   434 a.a.
NCBI ID   WP_086297606.1    Uniprot ID   -
Organism   Enterococcus sp. CR-Ec1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2634257..2645561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXM95_RS12635 (CXM95_12635) - 2634466..2634891 (+) 426 WP_016613640.1 AsnC family transcriptional regulator -
  CXM95_RS12645 (CXM95_12645) - 2635207..2635557 (-) 351 WP_086297585.1 type II toxin-antitoxin system PemK/MazF family toxin -
  CXM95_RS12650 (CXM95_12650) - 2635551..2635814 (-) 264 WP_086297597.1 PbsX family transcriptional regulator -
  CXM95_RS12655 (CXM95_12655) - 2636101..2636268 (-) 168 WP_016621416.1 PTS glucose transporter subunit IIA -
  CXM95_RS12660 (CXM95_12660) - 2636614..2636712 (-) 99 WP_074534955.1 type I toxin-antitoxin system Fst family toxin -
  CXM95_RS12665 (CXM95_12665) map 2636800..2637558 (-) 759 WP_086297604.1 type I methionyl aminopeptidase -
  CXM95_RS12670 (CXM95_12670) truA 2637601..2638338 (-) 738 WP_005225435.1 tRNA pseudouridine(38-40) synthase TruA -
  CXM95_RS12675 (CXM95_12675) rlmH 2638404..2638883 (-) 480 WP_008379108.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CXM95_RS12680 (CXM95_12680) htrA 2639257..2640561 (+) 1305 WP_086297606.1 trypsin-like peptidase domain-containing protein Regulator
  CXM95_RS12685 (CXM95_12685) - 2640641..2641255 (-) 615 WP_101699228.1 DUF4479 and tRNA-binding domain-containing protein -
  CXM95_RS12690 (CXM95_12690) - 2641528..2641989 (-) 462 WP_005225429.1 universal stress protein -
  CXM95_RS12695 (CXM95_12695) - 2642002..2642322 (-) 321 WP_026008043.1 thioredoxin family protein -
  CXM95_RS12700 (CXM95_12700) pepA 2642457..2643533 (-) 1077 WP_086299278.1 glutamyl aminopeptidase -
  CXM95_RS12710 (CXM95_12710) - 2643826..2644170 (+) 345 WP_005234590.1 peptidase -
  CXM95_RS12715 (CXM95_12715) - 2644231..2645265 (-) 1035 WP_086297614.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44873.36 Da        Isoelectric Point: 4.0123

>NTDB_id=259120 CXM95_RS12680 WP_086297606.1 2639257..2640561(+) (htrA) [Enterococcus sp. CR-Ec1]
MSRKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSEDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDSYTDLAVLKISSEKVTTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=259120 CXM95_RS12680 WP_086297606.1 2639257..2640561(+) (htrA) [Enterococcus sp. CR-Ec1]
ATGTCAAGAAAATATGTCACACCAGGTAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTATATCTGGCAATGGGTTCATCCTTGACTTCAACACCAGAAACCACGA
CCAACAGTGGGGTCCAAGATTCTAACGGGCAAACACAAGTATCTAATGTCAAACTTGATGTGACCAGCGATGTCACTGAA
GCAGTTGAAAAAGTACAAGATTCCGTCGTTTCCATCATTAATTTACAACAAAGTCAAAGCAACGATTGGAACAGCCTCTT
TGGTCAGCAAGGTGGACAAAGTGAAGGCGATAGCCAAAGCGAAGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGGAGTG
GTGTCATTTACAAAATCGATGGCGACGATGCCTATGTCGTAACCAACAACCACGTAGTTGAAGGTCAAGATGGTTTGGAA
GTTGTCTTAGCAGATGGTACAAAAGTCAAAGCTGAATTGGTAGGTACCGATTCTTACACAGACTTAGCCGTCTTAAAAAT
CTCTTCTGAAAAAGTTACAACTGCCGCAACATTTGGCGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCAATCGCGATTG
GTTCTCCTCTAGGCTCTGACTACGCAAACTCTGTGACACAAGGGATCGTGTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGTATCAACGCGATCCAAACGGATGCTGCAATCAACCCAGGAAACTCTGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGTTCTGCGTCAGGCGTTAGTG
TCGAAGGAATGGGCTTTGCGATTCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTC
CGCCCTGCACTAGGGATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCAGGCGTTGTGATCTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATCACGAAGATTGATGATACAGAAGTCAGCACAACAACGGATCTACAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACAGCAGAAGTAAAACTTTCCGTTGATACATCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(18-420)

PDZ domain (PDZ_2)

(322-419)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.927

91.475

0.521
  htrA Streptococcus gordonii str. Challis substr. CH1

51.074

96.544

0.493
  htrA Streptococcus mitis NCTC 12261

55.989

82.719

0.463
  htrA Streptococcus pneumoniae TIGR4

57.602

78.802

0.454
  htrA Streptococcus pneumoniae D39

57.602

78.802

0.454
  htrA Streptococcus pneumoniae Rx1

57.602

78.802

0.454
  htrA Streptococcus pneumoniae R6

57.602

78.802

0.454

Multiple sequence alignment