Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CWI26_RS10230 Genome accession   NZ_CP025043
Coordinates   2066519..2067241 (-) Length   240 a.a.
NCBI ID   WP_029177367.1    Uniprot ID   A0A0M9FHH4
Organism   Streptococcus suis strain AH681     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2061519..2072241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS10215 (CWI26_10215) sufC 2062362..2063135 (-) 774 WP_024376584.1 Fe-S cluster assembly ATPase SufC -
  CWI26_RS10220 (CWI26_10220) - 2063870..2065246 (+) 1377 WP_100881707.1 IS1182 family transposase -
  CWI26_RS10225 (CWI26_10225) - 2065350..2066522 (-) 1173 WP_100881708.1 glycosyltransferase family 4 protein -
  CWI26_RS10230 (CWI26_10230) mecA 2066519..2067241 (-) 723 WP_029177367.1 adaptor protein MecA Regulator
  CWI26_RS10235 (CWI26_10235) - 2067369..2068208 (-) 840 WP_024377889.1 undecaprenyl-diphosphate phosphatase -
  CWI26_RS10240 (CWI26_10240) - 2068330..2069895 (+) 1566 WP_044781720.1 ABC transporter substrate-binding protein/permease -
  CWI26_RS10245 (CWI26_10245) - 2069888..2070631 (+) 744 WP_100881709.1 amino acid ABC transporter ATP-binding protein -
  CWI26_RS10250 (CWI26_10250) - 2070758..2070967 (-) 210 WP_009910800.1 hypothetical protein -
  CWI26_RS10255 (CWI26_10255) - 2071053..2071955 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28007.53 Da        Isoelectric Point: 4.0497

>NTDB_id=257628 CWI26_RS10230 WP_029177367.1 2066519..2067241(-) (mecA) [Streptococcus suis strain AH681]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDFSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=257628 CWI26_RS10230 WP_029177367.1 2066519..2067241(-) (mecA) [Streptococcus suis strain AH681]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGTGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTAGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTTTCGGAACTTGGTGATGTTGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTTTCACGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FHH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.23

100

0.521
  mecA Streptococcus pneumoniae D39

51.23

100

0.521
  mecA Streptococcus pneumoniae R6

51.23

100

0.521
  mecA Streptococcus pneumoniae TIGR4

51.23

100

0.521
  mecA Streptococcus mutans UA159

49.59

100

0.504
  mecA Streptococcus thermophilus LMD-9

47.083

100

0.471
  mecA Streptococcus thermophilus LMG 18311

46.667

100

0.467

Multiple sequence alignment