Detailed information NTG0257304

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: CWQ23_RS10675
• Genome accession: NZ_CP025026
• Coordinates: 2022213..2023442 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728356.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SGEHI2015-113
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2017213..2028442

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWQ23_RS10650 (CWQ23_10650)	-	2018373..2020952 (+)	2580	WP_000154433.1	YfhO family protein	-
CWQ23_RS10670 (CWQ23_10670)	rlmH	2021533..2022012 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
CWQ23_RS10675 (CWQ23_10675)	htrA	2022213..2023442 (+)	1230	WP_000728356.1	trypsin-like peptidase domain-containing protein	Regulator
CWQ23_RS10680 (CWQ23_10680)	spo0J	2023540..2024313 (+)	774	WP_000456088.1	ParB/RepB/Spo0J family partition protein	Regulator
CWQ23_RS10685 (CWQ23_10685)	dnaA	2024522..2025883 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
CWQ23_RS10690 (CWQ23_10690)	dnaN	2026038..2027174 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
CWQ23_RS10695 (CWQ23_10695)	-	2027232..2028125 (+)	894	WP_000987448.1	diacylglycerol kinase family protein	-
CWQ23_RS10700 (CWQ23_10700)	-	2028135..2028332 (+)	198	WP_000285199.1	DUF951 family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43104.56 Da
• Isoelectric Point: 9.5271

>NTDB_id=257304 CWQ23_RS10675 WP_000728356.1 2022213..2023442(+) (htrA) [Streptococcus agalactiae strain SGEHI2015-113]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTITIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=257304 CWQ23_RS10675 WP_000728356.1 2022213..2023442(+) (htrA) [Streptococcus agalactiae strain SGEHI2015-113]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATCACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTACCGTGGTGAAAATAAACAAACAATCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.104	96.088	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.533	97.311	0.55
htrA	Streptococcus pneumoniae TIGR4	55.037	99.511	0.548
htrA	Streptococcus pneumoniae Rx1	55.037	99.511	0.548
htrA	Streptococcus pneumoniae D39	55.037	99.511	0.548
htrA	Streptococcus pneumoniae R6	55.037	99.511	0.548