Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CVO91_RS10855 Genome accession   NZ_CP024974
Coordinates   2129692..2130414 (-) Length   240 a.a.
NCBI ID   WP_002938171.1    Uniprot ID   A0A116M1G6
Organism   Streptococcus suis strain CZ130302     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2124692..2135414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS10840 (CVO91_10840) sufD 2125801..2127063 (-) 1263 WP_033875545.1 Fe-S cluster assembly protein SufD -
  CVO91_RS10845 (CVO91_10845) sufC 2127080..2127853 (-) 774 WP_002942293.1 Fe-S cluster assembly ATPase SufC -
  CVO91_RS10850 (CVO91_10850) - 2128523..2129695 (-) 1173 WP_002942284.1 MraY family glycosyltransferase -
  CVO91_RS10855 (CVO91_10855) mecA 2129692..2130414 (-) 723 WP_002938171.1 adaptor protein MecA Regulator
  CVO91_RS10860 (CVO91_10860) - 2130542..2131381 (-) 840 WP_024377889.1 undecaprenyl-diphosphate phosphatase -
  CVO91_RS10865 (CVO91_10865) - 2131505..2133070 (+) 1566 WP_002942280.1 ABC transporter substrate-binding protein/permease -
  CVO91_RS10870 (CVO91_10870) - 2133063..2133806 (+) 744 WP_002942278.1 amino acid ABC transporter ATP-binding protein -
  CVO91_RS10875 (CVO91_10875) - 2133874..2135226 (-) 1353 WP_004195537.1 IS66-like element short variant transposase -
  CVO91_RS10880 (CVO91_10880) - 2135180..2135386 (-) 207 WP_002941576.1 hypothetical protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27973.51 Da        Isoelectric Point: 4.0497

>NTDB_id=256945 CVO91_RS10855 WP_002938171.1 2129692..2130414(-) (mecA) [Streptococcus suis strain CZ130302]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=256945 CVO91_RS10855 WP_002938171.1 2129692..2130414(-) (mecA) [Streptococcus suis strain CZ130302]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTTGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTTTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116M1G6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment