Detailed information NTG0256817

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: CV098_RS08645
• Genome accession: NZ_CP024958
• Coordinates: 1821747..1823903 (-)
• Length: 718 a.a.
• NCBI ID: WP_017864912.1
• Uniprot ID: A0AAE4T0Y4
• Organism: Lactococcus lactis subsp. lactis strain G423
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1816747..1828903

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV098_RS08620 (CV098_08620)	-	1818424..1818951 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
CV098_RS08625 (CV098_08625)	atpF	1818953..1819459 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
CV098_RS08630 (CV098_08630)	atpB	1819474..1820187 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
CV098_RS08635 (CV098_08635)	-	1820232..1820447 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
CV098_RS08640 (CV098_08640)	-	1820632..1821408 (-)	777	WP_017864911.1	alpha/beta hydrolase	-
CV098_RS08645 (CV098_08645)	comEC	1821747..1823903 (-)	2157	WP_017864912.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
CV098_RS08650 (CV098_08650)	comEA	1823884..1824531 (-)	648	WP_017864913.1	ComEA family DNA-binding protein	Machinery gene
CV098_RS08655 (CV098_08655)	-	1824591..1825952 (-)	1362	WP_017864914.1	ABC transporter permease	-
CV098_RS08660 (CV098_08660)	-	1825949..1826881 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
CV098_RS08665 (CV098_08665)	-	1826987..1827385 (-)	399	WP_004255236.1	hypothetical protein	-
CV098_RS08670 (CV098_08670)	-	1827489..1828052 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 82234.53 Da
• Isoelectric Point: 9.5820

>NTDB_id=256817 CV098_RS08645 WP_017864912.1 1821747..1823903(-) (comEC) [Lactococcus lactis subsp. lactis strain G423]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTIGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKGRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQK

Nucleotide

• Length: 2157 bp

>NTDB_id=256817 CV098_RS08645 WP_017864912.1 1821747..1823903(-) (comEC) [Lactococcus lactis subsp. lactis strain G423]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTATTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGTCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAATAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAGGAA
GACAAATAATTTTTGCAGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGCCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (206-446)

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	77.159	100	0.772
comEC/celB	Streptococcus mitis SK321	44.766	100	0.453
comEC/celB	Streptococcus mitis NCTC 12261	44.613	100	0.45
comEC/celB	Streptococcus pneumoniae TIGR4	43.862	100	0.443
comEC/celB	Streptococcus pneumoniae Rx1	43.448	100	0.439
comEC/celB	Streptococcus pneumoniae D39	43.448	100	0.439
comEC/celB	Streptococcus pneumoniae R6	43.448	100	0.439