Detailed information NTG0256720

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: CV702_RS08910
• Genome accession: NZ_CP024954
• Coordinates: 1878004..1880160 (-)
• Length: 718 a.a.
• NCBI ID: WP_017864912.1
• Uniprot ID: A0AAE4T0Y4
• Organism: Lactococcus lactis subsp. lactis strain F44
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1873004..1885160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV702_RS08885 (CV702_08895)	-	1874681..1875208 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
CV702_RS08890 (CV702_08900)	atpF	1875210..1875716 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
CV702_RS08895 (CV702_08905)	atpB	1875731..1876444 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
CV702_RS08900 (CV702_08910)	-	1876489..1876704 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
CV702_RS08905 (CV702_08915)	-	1876889..1877665 (-)	777	WP_017864911.1	alpha/beta hydrolase	-
CV702_RS08910 (CV702_08920)	comEC	1878004..1880160 (-)	2157	WP_017864912.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
CV702_RS08915 (CV702_08925)	comEA	1880141..1880788 (-)	648	WP_017864913.1	ComEA family DNA-binding protein	Machinery gene
CV702_RS08920 (CV702_08930)	-	1880848..1882209 (-)	1362	WP_017864914.1	ABC transporter permease	-
CV702_RS08925 (CV702_08935)	-	1882206..1883138 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
CV702_RS08930 (CV702_08940)	-	1883244..1883642 (-)	399	WP_004255236.1	hypothetical protein	-
CV702_RS08935 (CV702_08945)	-	1883746..1884309 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 82234.53 Da
• Isoelectric Point: 9.5820

>NTDB_id=256720 CV702_RS08910 WP_017864912.1 1878004..1880160(-) (comEC) [Lactococcus lactis subsp. lactis strain F44]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTIGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKGRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQK

Nucleotide

• Length: 2157 bp

>NTDB_id=256720 CV702_RS08910 WP_017864912.1 1878004..1880160(-) (comEC) [Lactococcus lactis subsp. lactis strain F44]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTATTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGTCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAATAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAGGAA
GACAAATAATTTTTGCAGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGCCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (206-446)

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	77.159	100	0.772
comEC/celB	Streptococcus mitis SK321	44.766	100	0.453
comEC/celB	Streptococcus mitis NCTC 12261	44.613	100	0.45
comEC/celB	Streptococcus pneumoniae TIGR4	43.862	100	0.443
comEC/celB	Streptococcus pneumoniae Rx1	43.448	100	0.439
comEC/celB	Streptococcus pneumoniae D39	43.448	100	0.439
comEC/celB	Streptococcus pneumoniae R6	43.448	100	0.439