Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   CTW00_RS09445 Genome accession   NZ_CP024843
Coordinates   1957158..1957868 (-) Length   236 a.a.
NCBI ID   WP_003101337.1    Uniprot ID   -
Organism   Streptococcus iniae strain FP5228     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1952158..1962868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CTW00_RS09430 (CTW00_01914) rnc 1954199..1954891 (-) 693 WP_003101331.1 ribonuclease III -
  CTW00_RS09435 (CTW00_01915) vicX 1954994..1955803 (-) 810 WP_003101333.1 MBL fold metallo-hydrolase Regulator
  CTW00_RS09440 (CTW00_01916) vicK 1955807..1957165 (-) 1359 WP_100185199.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CTW00_RS09445 (CTW00_01917) vicR 1957158..1957868 (-) 711 WP_003101337.1 response regulator YycF Regulator
  CTW00_RS09450 (CTW00_01918) - 1958125..1958922 (+) 798 WP_003101338.1 amino acid ABC transporter ATP-binding protein -
  CTW00_RS09455 (CTW00_01919) - 1958919..1959737 (+) 819 WP_003101339.1 transporter substrate-binding domain-containing protein -
  CTW00_RS09460 (CTW00_01920) - 1959752..1960453 (+) 702 WP_003101340.1 amino acid ABC transporter permease -
  CTW00_RS09465 (CTW00_01921) - 1960469..1961116 (+) 648 WP_003101341.1 amino acid ABC transporter permease -
  CTW00_RS09470 (CTW00_01922) - 1961154..1962161 (-) 1008 WP_003101345.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27044.87 Da        Isoelectric Point: 5.0030

>NTDB_id=255837 CTW00_RS09445 WP_003101337.1 1957158..1957868(-) (vicR) [Streptococcus iniae strain FP5228]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAVTLFEEEKPDLVILDLMLPEMDGLEVAKEIRKTSHIPIVMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASAGNQELTIGNLQILPDAFLAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSHD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=255837 CTW00_RS09445 WP_003101337.1 1957158..1957868(-) (vicR) [Streptococcus iniae strain FP5228]
ATGAAGAAAATTCTTATAGTTGATGATGAAAAACCGATTTCAGATATCATCAAATTTAATTTAACAAAAGAAGGATATGA
AACGGTGACAGCTTTTGATGGACGTGAAGCAGTTACCTTGTTTGAAGAAGAAAAACCAGACTTGGTTATTTTAGATTTGA
TGTTACCTGAAATGGATGGTTTAGAAGTTGCTAAAGAAATTCGTAAAACAAGCCACATTCCAATTGTTATGTTATCAGCA
AAAGATAGTGAGTTTGATAAGGTCATCGGTCTTGAAATTGGTGCAGATGACTATGTGACAAAACCATTTTCTAATCGTGA
GCTATTAGCTCGTGTTAAGGCGCATTTGCGCCGTACAGAAACCATCGAAACAGCAGTTGCTGAAGAAAATGCCTCAGCTG
GTAATCAAGAGTTAACGATTGGCAACCTTCAAATCTTGCCAGATGCCTTTTTAGCTAAAAAGCATGGTCAAGAGGTTGAG
TTAACCCACCGTGAATTTGAATTATTGCATCACTTAGCCAACCATATTGGGCAAGTAATGACTCGTGAACATTTGCTTGA
AACTGTTTGGGGCTATGATTATTTTGGTGATGTTAGAACAGTTGACGTAACGGTACGTCGTTTGCGAGAAAAAATCGAAG
ATACTCCTAGCCGTCCTGAATATATTTTGACAAGACGAGGAGTTGGATACTACATGAAATCACATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.136

100

0.881
  micA Streptococcus pneumoniae Cp1015

77.872

99.576

0.775
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.534

98.305

0.428
  scnR Streptococcus mutans UA159

37.768

98.729

0.373

Multiple sequence alignment