Detailed information NTG0255828

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: CTW00_RS07545
• Genome accession: NZ_CP024843
• Coordinates: 1558808..1559653 (+)
• Length: 281 a.a.
• NCBI ID: WP_003099573.1
• Uniprot ID: A0A1J0MYY1
• Organism: Streptococcus iniae strain FP5228
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1553808..1564653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CTW00_RS07520 (CTW00_01524)	-	1553931..1555253 (+)	1323	WP_225111305.1	PTS sugar transporter subunit IIC	-
CTW00_RS07525 (CTW00_01525)	-	1555250..1556089 (+)	840	WP_003099563.1	alpha/beta hydrolase	-
CTW00_RS07530 (CTW00_01526)	ylqF	1556558..1557412 (+)	855	WP_003099566.1	ribosome biogenesis GTPase YlqF	-
CTW00_RS07535 (CTW00_01527)	-	1557396..1558181 (+)	786	WP_003099568.1	ribonuclease HII	-
CTW00_RS07540 (CTW00_01528)	-	1558194..1558742 (+)	549	WP_003099570.1	sugar O-acetyltransferase	-
CTW00_RS07545 (CTW00_01529)	dprA	1558808..1559653 (+)	846	WP_003099573.1	DNA-processing protein DprA	Machinery gene
CTW00_RS07550 (CTW00_01530)	topA	1559750..1561885 (+)	2136	WP_003099575.1	type I DNA topoisomerase	-
CTW00_RS07555 (CTW00_01531)	-	1561979..1562863 (-)	885	WP_003099578.1	LysR family transcriptional regulator	-
CTW00_RS07560 (CTW00_01532)	-	1563029..1564087 (+)	1059	WP_003099589.1	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31550.74 Da
• Isoelectric Point: 9.9826

>NTDB_id=255828 CTW00_RS07545 WP_003099573.1 1558808..1559653(+) (dprA) [Streptococcus iniae strain FP5228]
MNNFELYKLKKAGLKNHHILNIIHYSQQTKKSLSLRNMAVVSGTSKPCLFLENYKLLNIKELRVEFKKYPSFSILDKTYP
LALKEIDNPPVLLFYQGNLELLNRHKLAVVGSRKSSAVGNKSVESLIKQLNNQFVIVSGLARGIDTVAHFSSIKQGGETI
AVIGSGLDIYYPKENRRLQEFIAEKHLLLSEYCPKEAPLAHHFPERNRIIAGLSMGVLVAEAKWRSGSLITCRFALDYGR
DIFVVPGAILDKQSQGGNHLIQEGAKLVTKGLDIISEYQFL

Nucleotide

• Length: 846 bp

>NTDB_id=255828 CTW00_RS07545 WP_003099573.1 1558808..1559653(+) (dprA) [Streptococcus iniae strain FP5228]
ATGAATAACTTTGAACTGTATAAATTAAAGAAAGCTGGCCTAAAAAATCATCATATTCTAAATATCATTCATTATAGCCA
GCAAACTAAGAAATCTCTATCACTTAGAAATATGGCTGTTGTTTCAGGAACAAGTAAACCATGTCTGTTTTTAGAAAATT
ACAAGCTGTTAAATATAAAAGAGTTACGAGTAGAATTTAAGAAGTATCCCAGCTTTTCAATTTTAGACAAGACCTATCCC
CTTGCTTTAAAAGAAATTGATAATCCGCCAGTATTATTATTTTATCAAGGAAATTTAGAGCTTTTAAATCGGCATAAATT
AGCAGTGGTAGGGTCAAGGAAATCCTCAGCAGTTGGAAACAAATCTGTTGAATCTCTCATCAAGCAACTTAATAATCAGT
TTGTTATTGTTAGTGGGTTGGCTAGAGGAATTGATACTGTAGCTCATTTTTCGAGCATCAAACAAGGTGGAGAGACTATT
GCTGTTATTGGATCAGGGTTAGACATTTATTATCCTAAGGAAAATAGAAGATTACAGGAGTTTATTGCTGAAAAGCATTT
ATTATTAAGTGAATATTGCCCTAAGGAAGCACCTTTAGCACATCATTTTCCAGAACGAAATCGCATAATTGCAGGCTTAT
CTATGGGAGTTTTAGTGGCAGAAGCCAAATGGCGTTCTGGTAGTCTAATCACTTGTCGCTTTGCACTTGATTACGGTAGG
GATATTTTTGTTGTTCCAGGCGCCATCCTTGACAAACAGTCGCAGGGAGGGAATCACCTCATTCAAGAGGGAGCGAAGCT
TGTTACAAAAGGACTTGACATCATTTCTGAATACCAATTTTTATAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

3D structure

• AlphaFold DB: A0A1J0MYY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.786	99.644	0.665
dprA/cilB/dalA	Streptococcus mitis SK321	57.5	99.644	0.573
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae D39	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae R6	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	56.786	99.644	0.566
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.644	0.544