Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CTW00_RS07360 Genome accession   NZ_CP024843
Coordinates   1519334..1520008 (+) Length   224 a.a.
NCBI ID   WP_003099507.1    Uniprot ID   -
Organism   Streptococcus iniae strain FP5228     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1514334..1525008
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CTW00_RS07345 (CTW00_01489) pstB 1515148..1515906 (+) 759 WP_003099501.1 phosphate ABC transporter ATP-binding protein PstB -
  CTW00_RS07350 (CTW00_01490) phoU 1515961..1516614 (+) 654 WP_003099503.1 phosphate signaling complex protein PhoU -
  CTW00_RS07355 (CTW00_01491) - 1516676..1519213 (+) 2538 WP_003099506.1 M1 family metallopeptidase -
  CTW00_RS07360 (CTW00_01492) ciaR 1519334..1520008 (+) 675 WP_003099507.1 response regulator transcription factor Regulator
  CTW00_RS07365 (CTW00_01493) ciaH 1520001..1521311 (+) 1311 WP_003099509.1 HAMP domain-containing sensor histidine kinase Regulator
  CTW00_RS07370 (CTW00_01494) rpsT 1521483..1521725 (-) 243 WP_080613191.1 30S ribosomal protein S20 -
  CTW00_RS07375 (CTW00_01495) coaA 1521785..1522705 (-) 921 WP_003099512.1 type I pantothenate kinase -
  CTW00_RS07380 (CTW00_01496) - 1522966..1523565 (+) 600 WP_003099513.1 class I SAM-dependent methyltransferase -
  CTW00_RS07385 (CTW00_01497) - 1523552..1524829 (+) 1278 WP_003099515.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25562.41 Da        Isoelectric Point: 4.3757

>NTDB_id=255826 CTW00_RS07360 WP_003099507.1 1519334..1520008(+) (ciaR) [Streptococcus iniae strain FP5228]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGFYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KESLDDKGHGFDLGADDYLTKPFYLEELKMRIQALLKRTGKMTTSQLSYGNISIDTERNMVKVGDTTIELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVDNLQTLRSVGYILKTNG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=255826 CTW00_RS07360 WP_003099507.1 1519334..1520008(+) (ciaR) [Streptococcus iniae strain FP5228]
ATGATAAAAATATTACTTGTTGAAGATGATTTAAGTTTATCTAATTCGATTTTTGATTTTTTAGATGATTTTGCTGATGT
TATGCAGGTTTTTGATGGAGATGAAGGTTTTTATGAGGCTGAAAGTGGTGTTTATGATCTTATTCTCCTGGACTTAATGT
TACCTGAAAAAAATGGTTTTCAAGTCCTAAAAGAATTAAGAGAAAAAGACATCAAAACGCCTGTTCTTATTATGACTGCT
AAAGAAAGTCTTGACGATAAAGGGCATGGCTTTGACCTTGGAGCTGATGACTACCTAACCAAACCATTTTATTTAGAGGA
GCTAAAAATGCGTATTCAAGCCCTCTTGAAACGAACTGGTAAGATGACTACCAGTCAGCTATCTTATGGGAATATCAGTA
TTGATACTGAACGAAATATGGTAAAAGTCGGAGACACTACCATTGAGCTTCTTGGAAAAGAGTATGATTTACTCATTTAT
CTCCTTCAAAATCAAAATGTTATTTTACCTAAATCACAGATTTTTGACCGTATATGGGGATTCGACAGTGATACCACAAT
ATCAGTTGTAGAGGTTTATGTTTCAAAAATCAGAAAAAAACTAAAAGGGACAGATTTTGTAGACAACCTTCAAACGCTTA
GAAGTGTCGGATACATCTTAAAAACAAATGGCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.767

100

0.393
  covR Streptococcus salivarius strain HSISS4

36.726

100

0.371

Multiple sequence alignment