Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   CTW00_RS00400 Genome accession   NZ_CP024843
Coordinates   70930..72834 (-) Length   634 a.a.
NCBI ID   WP_003101755.1    Uniprot ID   -
Organism   Streptococcus iniae strain FP5228     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 65930..77834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CTW00_RS00370 (CTW00_00076) tnpA 66091..66555 (+) 465 Protein_67 IS200/IS605 family transposase -
  CTW00_RS00375 (CTW00_00077) - 66691..67047 (-) 357 WP_003101745.1 S1 RNA-binding domain-containing protein -
  CTW00_RS00380 (CTW00_00078) - 67047..68447 (-) 1401 WP_003101746.1 Cof-type HAD-IIB family hydrolase -
  CTW00_RS00385 (CTW00_00079) - 68480..69124 (-) 645 WP_003101747.1 response regulator transcription factor -
  CTW00_RS00390 (CTW00_00080) - 69117..70121 (-) 1005 WP_003101748.1 sensor histidine kinase -
  CTW00_RS00395 (CTW00_00081) liaF 70118..70813 (-) 696 WP_003101751.1 cell wall-active antibiotics response protein LiaF -
  CTW00_RS00400 (CTW00_00082) pknB 70930..72834 (-) 1905 WP_003101755.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  CTW00_RS00405 (CTW00_00083) - 72831..73571 (-) 741 WP_003101757.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  CTW00_RS00410 (CTW00_00084) rsmB 73609..74931 (-) 1323 WP_003101760.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CTW00_RS00415 (CTW00_00085) fmt 74921..75856 (-) 936 WP_003101762.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 634 a.a.        Molecular weight: 69124.80 Da        Isoelectric Point: 8.9521

>NTDB_id=255791 CTW00_RS00400 WP_003101755.1 70930..72834(-) (pknB) [Streptococcus iniae strain FP5228]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYIQGADLKKFIQDNAPLSNTQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPQVP
QALENVVIKATAKKLSDRYNSTFEMSRDLMTALSYNRSRERKLVFLDVESTKPLPKVTPTPAPKPTVAPVSPSNTTKQKQ
EAIADVPVKKKKSGRFFGTLLKIIFALFVIGVAFFAFLVLTKPSTVKVPNVNGSSLAVAESELKSLGFKIGKVKEIESAT
VAEGNVVKTDPEAGTSKREGSKVDIYVSIGNQSFVMEDYKNQLYEDAVENLVNTYNVPRSKIKIERVVTSDYRKDMVIAQ
SPSPGEKFNPKGKSKIVLSVASNDTVLMPTIVNYTYQDALAALKALGIDSKRVKAYYPDVNSATGFSKMPNPKSTMIISA
QDPYAGVEISLSATSEISIYLYAEEPTANSSDTTTSSNSRSTASSSESHATSSSSSNPNAGTETNTDANVSPQN

Nucleotide


Download         Length: 1905 bp        

>NTDB_id=255791 CTW00_RS00400 WP_003101755.1 70930..72834(-) (pknB) [Streptococcus iniae strain FP5228]
ATGATACAGATTGGCAAATTATTTGCTGGTCGTTATCGCATCTTAAAATCAATTGGCCGCGGTGGTATGGCGGATGTTTA
CTTAGCCAATGACTTAATCTTAGATAATGAAGAAGTTGCAATTAAAGTTTTGCGAACCAATTATCAAACAGATCAAGTTG
CAGTAGCGCGTTTCCAAAGAGAAGCGCGAGCGATGGCAGAATTAAATCATCCCAACATTGTCGCTATTCGAGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATATCCAGGGCGCTGACCTTAAGAAATTTATTCAAGATAACGCTCC
TTTGTCTAACACCCAAGTTGTTAGAATCATGGAAGAAGTTTTATCTGCTATGACATTAGCCCACCAAAAAGGGATTGTTC
ATAGAGACTTGAAACCTCAAAATATTCTATTAACAAAGTCAGGTGTTGTCAAAGTTACAGACTTTGGTATTGCTGTAGCT
TTTGCTGAAACTAGTTTAACGCAGACAAATTCCATGTTAGGAAGTGTGCATTATTTATCACCAGAACAAGCCCGTGGTTC
AAAAGCCACCATTCAAAGTGATATTTATGCCATGGGAATTATGCTCTTTGAAATGTTAACAGGTCATATCCCATATGATG
GTGATAGTGCTGTTACAATTGCATTGCAGCATTTCCAAAAACCCCTTCCTTCAATTATTGACGAGAACCCGCAAGTTCCA
CAGGCTTTAGAAAATGTTGTTATTAAGGCAACTGCTAAAAAGTTAAGTGATCGTTACAATTCGACATTTGAAATGAGTCG
CGACCTAATGACTGCACTAAGTTATAATCGAAGCCGTGAACGCAAGTTAGTCTTTTTGGATGTTGAAAGCACAAAACCCT
TACCAAAAGTAACCCCGACCCCAGCACCAAAACCAACGGTAGCTCCGGTAAGTCCAAGTAATACCACTAAACAAAAACAA
GAAGCCATTGCTGATGTGCCTGTTAAGAAAAAAAAGAGTGGGCGTTTCTTTGGAACTTTATTAAAGATTATTTTTGCACT
ATTTGTTATCGGTGTTGCGTTTTTTGCCTTTCTTGTCTTGACCAAGCCATCTACCGTAAAAGTTCCAAATGTTAATGGAA
GTAGTCTAGCGGTTGCTGAATCAGAGTTAAAATCTTTAGGGTTTAAGATTGGAAAAGTAAAAGAAATTGAGAGTGCAACC
GTTGCAGAAGGTAATGTTGTTAAAACAGATCCAGAAGCTGGAACTTCAAAACGCGAAGGCTCTAAGGTTGATATTTATGT
TTCAATAGGTAATCAGAGTTTTGTGATGGAAGATTATAAAAATCAACTTTACGAAGATGCCGTTGAAAACCTTGTTAACA
CCTACAATGTTCCAAGGTCGAAAATTAAAATTGAAAGAGTGGTAACATCCGACTATCGTAAGGATATGGTTATTGCCCAG
TCACCTAGTCCAGGTGAGAAATTTAATCCCAAAGGAAAATCGAAGATTGTCCTCAGTGTGGCTAGTAATGACACAGTTTT
AATGCCAACTATTGTTAACTATACTTATCAGGATGCCCTTGCAGCACTAAAAGCTTTAGGAATTGACAGTAAGCGTGTCA
AAGCTTATTATCCTGATGTTAACTCTGCTACTGGCTTTAGCAAGATGCCTAATCCAAAATCAACAATGATTATCAGCGCA
CAAGATCCATATGCAGGTGTAGAGATTTCCTTATCTGCTACTAGCGAGATTAGCATTTACCTTTATGCTGAAGAACCAAC
AGCCAATAGTTCTGATACAACAACATCATCAAACAGTCGAAGTACAGCATCAAGTAGTGAGAGTCATGCCACAAGCAGCT
CATCCTCTAACCCTAACGCAGGTACCGAAACAAACACCGATGCCAATGTATCACCTCAAAACTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-241)

PASTA domain (PASTA)

(366-428)

PASTA domain (PASTA)

(435-501)

PASTA domain (PASTA)

(506-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

63.884

92.587

0.591
  stkP/pknB Streptococcus salivarius strain HSISS4

63.763

90.536

0.577
  stkP Streptococcus pneumoniae TIGR4

56.977

81.388

0.464
  stkP Streptococcus pneumoniae D39

56.589

81.388

0.461
  stkP Streptococcus pneumoniae R6

56.589

81.388

0.461
  stkP Streptococcus pneumoniae Rx1

56.395

81.388

0.459

Multiple sequence alignment