Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DLJ52_RS01210 Genome accession   NZ_CP029559
Coordinates   218151..218954 (+) Length   267 a.a.
NCBI ID   WP_109982380.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NIDR 6715-15     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 213151..223954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ52_RS01195 (DLJ52_01195) - 213226..214770 (-) 1545 WP_109982377.1 ABC transporter permease subunit -
  DLJ52_RS01200 (DLJ52_01200) - 214947..216872 (+) 1926 WP_109982378.1 DUF2207 domain-containing protein -
  DLJ52_RS01205 (DLJ52_01205) - 217128..217970 (+) 843 WP_109982379.1 undecaprenyl-diphosphate phosphatase -
  DLJ52_RS01210 (DLJ52_01210) mecA 218151..218954 (+) 804 WP_109982380.1 adaptor protein MecA Regulator
  DLJ52_RS01215 (DLJ52_01215) - 218958..220121 (+) 1164 WP_019769031.1 glycosyltransferase family 4 protein -
  DLJ52_RS01220 (DLJ52_01220) sufC 220743..221513 (+) 771 WP_002962472.1 Fe-S cluster assembly ATPase SufC -
  DLJ52_RS01225 (DLJ52_01225) sufD 222242..223504 (+) 1263 WP_109982381.1 Fe-S cluster assembly protein SufD -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30338.12 Da        Isoelectric Point: 4.1351

>NTDB_id=254067 DLJ52_RS01210 WP_109982380.1 218151..218954(+) (mecA) [Streptococcus sobrinus strain NIDR 6715-15]
MEMKQINESTLKISVSLDDLDSYGMELKDFLMPQEKTEEFFYTILDELDIPDSFKSTGMLSFRVTPRKDRIDVFVTKSEL
NESLDFEQLAQDMGDMSDMNPEDFFKNLEKNMMAQGDTEAHEKLKNLEAMLDDAISGLPLEDGKSGTTSSEDDEEDTFFK
IKEEDFIPITSYAHYVADFPSLEAAIVAAKALAVPTEASELFKSEEGYHLAVLFSVEDEDQLRAKQLQAHLLEYGDPARH
TRAYLLEHAVKLLEHTAVKQLKLIDLV

Nucleotide


Download         Length: 804 bp        

>NTDB_id=254067 DLJ52_RS01210 WP_109982380.1 218151..218954(+) (mecA) [Streptococcus sobrinus strain NIDR 6715-15]
ATGGAAATGAAACAAATTAATGAGTCAACGCTCAAGATTTCGGTGAGTCTTGACGATTTGGACTCATATGGCATGGAATT
AAAAGATTTCCTCATGCCTCAAGAAAAAACAGAAGAATTTTTCTACACAATATTGGACGAATTAGATATTCCGGATAGCT
TTAAATCAACAGGGATGTTAAGCTTTCGAGTGACTCCCCGCAAGGATCGCATTGATGTTTTTGTGACCAAATCTGAGCTC
AATGAAAGTCTAGATTTTGAGCAGTTGGCTCAAGATATGGGTGATATGTCAGACATGAATCCTGAAGATTTTTTCAAGAA
TCTTGAAAAGAATATGATGGCTCAGGGTGATACTGAGGCTCATGAAAAACTGAAGAATCTGGAGGCTATGCTGGACGATG
CAATCAGCGGGCTGCCCCTTGAGGATGGTAAGTCTGGAACGACGAGTTCAGAGGATGATGAAGAGGACACTTTCTTTAAA
ATCAAAGAGGAGGACTTTATTCCTATTACCAGTTATGCTCATTATGTGGCTGATTTTCCTAGTTTAGAAGCCGCTATCGT
AGCAGCCAAGGCTCTAGCAGTTCCAACCGAAGCTTCGGAACTTTTCAAATCTGAAGAAGGTTATCATTTGGCAGTTCTCT
TTAGTGTGGAAGATGAAGATCAGCTGAGAGCGAAACAGTTGCAGGCCCATCTCTTGGAATACGGAGATCCAGCTAGGCAC
ACCCGTGCTTACCTCTTGGAACATGCCGTCAAGCTCTTAGAACATACGGCGGTGAAACAATTGAAGCTAATAGATTTGGT
GTAG

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

47.727

98.876

0.472
  mecA Streptococcus thermophilus LMG 18311

47.529

98.502

0.468
  mecA Streptococcus thermophilus LMD-9

47.148

98.502

0.464
  mecA Streptococcus pneumoniae Rx1

40.299

100

0.404
  mecA Streptococcus pneumoniae D39

40.299

100

0.404
  mecA Streptococcus pneumoniae R6

40.299

100

0.404
  mecA Streptococcus pneumoniae TIGR4

39.925

100

0.401