Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | CTI08_RS15190 | Genome accession | NZ_CP024576 |
| Coordinates | 3094976..3096094 (+) | Length | 372 a.a. |
| NCBI ID | WP_000347039.1 | Uniprot ID | A0A9P2XLL8 |
| Organism | Acinetobacter baumannii strain AbPK1 | ||
| Function | mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 3055796..3129616 | 3094976..3096094 | within | 0 |
Gene organization within MGE regions
Location: 3055796..3129616
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CTI08_RS14975 (CTI08_14955) | - | 3056099..3056593 (+) | 495 | WP_002045790.1 | LexA family protein | - |
| CTI08_RS14980 (CTI08_14960) | - | 3056597..3057895 (+) | 1299 | WP_099715007.1 | Y-family DNA polymerase | - |
| CTI08_RS14985 (CTI08_14965) | - | 3057936..3058667 (+) | 732 | WP_099715009.1 | hypothetical protein | - |
| CTI08_RS20765 | - | 3058720..3059421 (+) | 702 | WP_223852316.1 | hypothetical protein | - |
| CTI08_RS14995 (CTI08_14975) | - | 3059459..3060025 (+) | 567 | WP_099715011.1 | hypothetical protein | - |
| CTI08_RS15000 (CTI08_14980) | - | 3060129..3060446 (-) | 318 | WP_099715013.1 | DUF6527 family protein | - |
| CTI08_RS15005 (CTI08_14985) | - | 3060447..3060992 (-) | 546 | WP_099715015.1 | glycoside hydrolase family 108 protein | - |
| CTI08_RS15010 (CTI08_14990) | - | 3061331..3062230 (-) | 900 | WP_099715017.1 | Bro-N domain-containing protein | - |
| CTI08_RS15015 (CTI08_14995) | - | 3062396..3062656 (+) | 261 | WP_000124483.1 | Arc family DNA-binding protein | - |
| CTI08_RS15020 (CTI08_15000) | - | 3062676..3063167 (-) | 492 | WP_001226299.1 | hypothetical protein | - |
| CTI08_RS15025 (CTI08_15005) | - | 3063224..3063550 (-) | 327 | WP_023188287.1 | hypothetical protein | - |
| CTI08_RS15030 (CTI08_15010) | - | 3063554..3063895 (-) | 342 | WP_000720515.1 | hypothetical protein | - |
| CTI08_RS15035 (CTI08_15015) | - | 3064094..3064483 (-) | 390 | WP_005138791.1 | hypothetical protein | - |
| CTI08_RS15040 (CTI08_15020) | - | 3064598..3068023 (-) | 3426 | WP_099715019.1 | host specificity factor TipJ family phage tail protein | - |
| CTI08_RS15045 (CTI08_15025) | - | 3068016..3068387 (-) | 372 | WP_322853271.1 | hypothetical protein | - |
| CTI08_RS15050 (CTI08_15030) | - | 3068380..3068742 (-) | 363 | WP_000835159.1 | hypothetical protein | - |
| CTI08_RS15055 (CTI08_15035) | - | 3068739..3069245 (-) | 507 | WP_000368369.1 | DUF1833 family protein | - |
| CTI08_RS15060 (CTI08_15040) | - | 3069245..3069643 (-) | 399 | WP_004714958.1 | hypothetical protein | - |
| CTI08_RS15075 (CTI08_15055) | - | 3071109..3072230 (+) | 1122 | WP_099715021.1 | ATP-binding protein | - |
| CTI08_RS15080 (CTI08_15060) | - | 3072227..3073186 (+) | 960 | WP_099715023.1 | hypothetical protein | - |
| CTI08_RS15085 (CTI08_15065) | - | 3073188..3073433 (+) | 246 | WP_000654847.1 | hypothetical protein | - |
| CTI08_RS15090 (CTI08_15070) | - | 3073437..3073886 (+) | 450 | WP_099715025.1 | DUF551 domain-containing protein | - |
| CTI08_RS15095 (CTI08_15075) | - | 3073883..3074092 (+) | 210 | WP_000028955.1 | hypothetical protein | - |
| CTI08_RS15100 (CTI08_15080) | - | 3074089..3074361 (+) | 273 | WP_099715027.1 | hypothetical protein | - |
| CTI08_RS20825 | - | 3074426..3074554 (+) | 129 | WP_002066592.1 | hypothetical protein | - |
| CTI08_RS15105 (CTI08_15085) | - | 3074565..3075233 (-) | 669 | WP_002037254.1 | hypothetical protein | - |
| CTI08_RS15110 (CTI08_15090) | - | 3075233..3076384 (-) | 1152 | WP_000947481.1 | tyrosine-type recombinase/integrase | - |
| CTI08_RS15120 (CTI08_15100) | ggt | 3077082..3079067 (-) | 1986 | WP_001042923.1 | gamma-glutamyltransferase | - |
| CTI08_RS15125 (CTI08_15105) | - | 3079370..3080893 (-) | 1524 | WP_099715029.1 | DHA2 family efflux MFS transporter permease subunit | - |
| CTI08_RS15130 (CTI08_15110) | - | 3080900..3082051 (-) | 1152 | WP_000128703.1 | EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit | - |
| CTI08_RS15135 (CTI08_15115) | - | 3082321..3082818 (-) | 498 | WP_002019577.1 | thioesterase family protein | - |
| CTI08_RS15140 (CTI08_15120) | hemB | 3082961..3083974 (+) | 1014 | WP_000222569.1 | porphobilinogen synthase | - |
| CTI08_RS15145 (CTI08_15125) | - | 3084000..3085115 (+) | 1116 | WP_000546701.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| CTI08_RS15150 (CTI08_15130) | - | 3085107..3086012 (-) | 906 | WP_001039356.1 | TIGR01777 family oxidoreductase | - |
| CTI08_RS15155 (CTI08_15135) | - | 3086102..3086554 (-) | 453 | WP_000164153.1 | ABZJ_00895 family protein | - |
| CTI08_RS15160 (CTI08_15140) | - | 3086934..3087311 (+) | 378 | WP_001059438.1 | VOC family protein | - |
| CTI08_RS15165 (CTI08_15145) | - | 3087379..3087852 (-) | 474 | WP_000974358.1 | OsmC family protein | - |
| CTI08_RS15170 (CTI08_15150) | - | 3088016..3089284 (+) | 1269 | WP_000116701.1 | exonuclease SbcCD subunit D | - |
| CTI08_RS15175 (CTI08_15155) | - | 3089294..3092890 (+) | 3597 | WP_000698785.1 | AAA family ATPase | - |
| CTI08_RS15180 (CTI08_15160) | - | 3093092..3093784 (-) | 693 | WP_001108512.1 | YggS family pyridoxal phosphate-dependent enzyme | - |
| CTI08_RS15185 (CTI08_15165) | pilT | 3093911..3094948 (+) | 1038 | WP_000355489.1 | type IV pilus twitching motility protein PilT | Machinery gene |
| CTI08_RS15190 (CTI08_15170) | pilU | 3094976..3096094 (+) | 1119 | WP_000347039.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| CTI08_RS15195 (CTI08_15175) | fur | 3096164..3096601 (-) | 438 | WP_001122847.1 | ferric iron uptake transcriptional regulator | - |
| CTI08_RS15200 (CTI08_15180) | - | 3096713..3097111 (+) | 399 | WP_001170994.1 | outer membrane protein assembly factor BamE | - |
| CTI08_RS15205 (CTI08_15185) | - | 3097166..3097489 (-) | 324 | WP_000442587.1 | RnfH family protein | - |
| CTI08_RS15210 (CTI08_15190) | - | 3097489..3098556 (-) | 1068 | WP_002019572.1 | hypothetical protein | - |
| CTI08_RS15220 (CTI08_15200) | - | 3098709..3099164 (-) | 456 | WP_000782976.1 | bacteriohemerythrin | - |
| CTI08_RS15225 (CTI08_15205) | - | 3099417..3100265 (-) | 849 | WP_000336548.1 | class II glutamine amidotransferase | - |
| CTI08_RS15230 (CTI08_15210) | - | 3100374..3101156 (-) | 783 | WP_000890283.1 | GNAT family N-acetyltransferase | - |
| CTI08_RS15235 (CTI08_15215) | argB | 3101277..3102185 (-) | 909 | WP_001135419.1 | acetylglutamate kinase | - |
| CTI08_RS15240 (CTI08_15220) | - | 3102200..3103618 (-) | 1419 | WP_001102845.1 | phosphomannomutase/phosphoglucomutase | - |
| CTI08_RS15245 (CTI08_15225) | dut | 3103818..3104270 (-) | 453 | WP_000868152.1 | dUTP diphosphatase | - |
| CTI08_RS15250 (CTI08_15230) | rep | 3104295..3106334 (-) | 2040 | WP_000093035.1 | DNA helicase Rep | - |
| CTI08_RS15255 (CTI08_15235) | - | 3106528..3107181 (-) | 654 | WP_001202415.1 | OmpA family protein | - |
| CTI08_RS15260 (CTI08_15240) | - | 3107426..3108352 (+) | 927 | WP_000100965.1 | acyltransferase | - |
| CTI08_RS15265 (CTI08_15245) | - | 3108369..3109415 (+) | 1047 | WP_001181639.1 | hypothetical protein | - |
| CTI08_RS15270 (CTI08_15250) | minC | 3109537..3110259 (+) | 723 | WP_000763677.1 | septum site-determining protein MinC | - |
| CTI08_RS15275 (CTI08_15255) | minD | 3110330..3111142 (+) | 813 | WP_001074362.1 | septum site-determining protein MinD | - |
| CTI08_RS15280 (CTI08_15260) | minE | 3111145..3111417 (+) | 273 | WP_000896934.1 | cell division topological specificity factor MinE | - |
| CTI08_RS15285 (CTI08_15265) | - | 3111501..3111788 (+) | 288 | WP_001218560.1 | PA4642 family protein | - |
| CTI08_RS15290 (CTI08_15270) | - | 3111936..3112580 (+) | 645 | WP_047936530.1 | tyrosyl-tRNA synthetase | - |
| CTI08_RS15295 (CTI08_15275) | rhtC | 3112636..3113256 (-) | 621 | WP_099715031.1 | threonine export protein RhtC | - |
| CTI08_RS15300 (CTI08_15280) | - | 3113406..3116438 (-) | 3033 | WP_000127823.1 | DNA translocase FtsK | - |
| CTI08_RS15305 (CTI08_15285) | trxB | 3116708..3117655 (+) | 948 | WP_001276144.1 | thioredoxin-disulfide reductase | - |
| CTI08_RS15310 (CTI08_15290) | aat | 3117775..3118506 (+) | 732 | WP_000854785.1 | leucyl/phenylalanyl-tRNA--protein transferase | - |
| CTI08_RS15315 (CTI08_15295) | - | 3118525..3119340 (+) | 816 | WP_000844343.1 | arginyltransferase | - |
| CTI08_RS15320 (CTI08_15300) | rimI | 3119385..3119840 (-) | 456 | WP_000621543.1 | ribosomal protein S18-alanine N-acetyltransferase | - |
| CTI08_RS15325 (CTI08_15305) | - | 3119949..3120824 (-) | 876 | WP_000992291.1 | metal-dependent hydrolase | - |
| CTI08_RS15330 (CTI08_15310) | - | 3121061..3121942 (-) | 882 | WP_000992305.1 | metal-dependent hydrolase | - |
| CTI08_RS15335 (CTI08_15315) | tuf | 3122146..3123336 (-) | 1191 | WP_001029610.1 | elongation factor Tu | - |
| CTI08_RS15340 (CTI08_15320) | fusA | 3123431..3125569 (-) | 2139 | WP_000113824.1 | elongation factor G | - |
| CTI08_RS15345 (CTI08_15325) | rpsG | 3125748..3126218 (-) | 471 | WP_001138055.1 | 30S ribosomal protein S7 | - |
| CTI08_RS15350 (CTI08_15330) | rpsL | 3126378..3126752 (-) | 375 | WP_000246374.1 | 30S ribosomal protein S12 | - |
| CTI08_RS15355 (CTI08_15335) | - | 3126953..3128278 (-) | 1326 | WP_000160011.1 | EcsC family protein | - |
Sequence
Protein
Download Length: 372 a.a. Molecular weight: 41933.13 Da Isoelectric Point: 6.6944
>NTDB_id=254047 CTI08_RS15190 WP_000347039.1 3094976..3096094(+) (pilU) [Acinetobacter baumannii strain AbPK1]
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRREFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRREFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
Nucleotide
Download Length: 1119 bp
>NTDB_id=254047 CTI08_RS15190 WP_000347039.1 3094976..3096094(+) (pilU) [Acinetobacter baumannii strain AbPK1]
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAACAGTCTTTCTGGGGAAGTGATTGGTCAACTGTTACATTCCA
TCATGAGTGAAAAACAACGCAGAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCGGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTTGTAGGCGCGACAG
GCACAGGTAAATCTACTTCACTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCTAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCAGATGAAGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAACAGTCTTTCTGGGGAAGTGATTGGTCAACTGTTACATTCCA
TCATGAGTGAAAAACAACGCAGAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCGGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTTGTAGGCGCGACAG
GCACAGGTAAATCTACTTCACTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCTAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCAGATGAAGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Acinetobacter baylyi ADP1 |
75.926 |
100 |
0.772 |
| pilU | Pseudomonas stutzeri DSM 10701 |
69.565 |
98.925 |
0.688 |
| pilU | Vibrio cholerae strain A1552 |
53.243 |
99.462 |
0.53 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
42.486 |
93.011 |
0.395 |