Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CR542_RS09840 Genome accession   NZ_CP024126
Coordinates   1915269..1915991 (-) Length   240 a.a.
NCBI ID   WP_012775334.1    Uniprot ID   -
Organism   Streptococcus suis strain HA0609     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1910269..1920991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR542_RS09820 (CR542_09780) - 1910340..1911566 (-) 1227 WP_002938158.1 cysteine desulfurase -
  CR542_RS09825 (CR542_09785) sufD 1911568..1912830 (-) 1263 WP_002938159.1 Fe-S cluster assembly protein SufD -
  CR542_RS09830 (CR542_09790) sufC 1912847..1913620 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  CR542_RS09835 (CR542_09795) - 1914100..1915272 (-) 1173 WP_002938168.1 glycosyltransferase family 4 protein -
  CR542_RS09840 (CR542_09800) mecA 1915269..1915991 (-) 723 WP_012775334.1 adaptor protein MecA Regulator
  CR542_RS09845 (CR542_09805) - 1916119..1916955 (-) 837 WP_013730561.1 undecaprenyl-diphosphate phosphatase -
  CR542_RS09850 (CR542_09810) - 1917082..1918647 (+) 1566 WP_013730562.1 ABC transporter substrate-binding protein/permease -
  CR542_RS09855 (CR542_09815) - 1918640..1919383 (+) 744 WP_009910795.1 amino acid ABC transporter ATP-binding protein -
  CR542_RS09860 (CR542_09820) - 1919506..1919715 (-) 210 WP_009910800.1 hypothetical protein -
  CR542_RS09865 (CR542_09825) - 1919801..1920703 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28000.54 Da        Isoelectric Point: 4.0497

>NTDB_id=252406 CR542_RS09840 WP_012775334.1 1915269..1915991(-) (mecA) [Streptococcus suis strain HA0609]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=252406 CR542_RS09840 WP_012775334.1 1915269..1915991(-) (mecA) [Streptococcus suis strain HA0609]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGTTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAACTTGAATTTTGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCAGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACAGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment