Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   C5B40_RS21540 Genome accession   NZ_CP028917
Coordinates   4550769..4551440 (-) Length   223 a.a.
NCBI ID   WP_003090494.1    Uniprot ID   A0A0H2ZC88
Organism   Pseudomonas aeruginosa strain JB2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4545769..4556440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5B40_RS21525 - 4546887..4549031 (+) 2145 WP_023517725.1 methyl-accepting chemotaxis protein -
  C5B40_RS21530 - 4549036..4549344 (-) 309 WP_003097699.1 hypothetical protein -
  C5B40_RS21535 carS 4549435..4550772 (-) 1338 WP_023875208.1 two-component system sensor histidine kinase CarS -
  C5B40_RS21540 ciaR 4550769..4551440 (-) 672 WP_003090494.1 two-component system response regulator CarR Regulator
  C5B40_RS21545 - 4551440..4551754 (-) 315 WP_003097704.1 PepSY domain-containing protein -
  C5B40_RS21550 - 4551754..4552062 (-) 309 WP_003090497.1 PepSY domain-containing protein -
  C5B40_RS21555 - 4552277..4553359 (+) 1083 WP_023875207.1 hypothetical protein -
  C5B40_RS21560 - 4553386..4554279 (+) 894 WP_003116712.1 hypothetical protein -
  C5B40_RS21565 - 4554263..4554529 (+) 267 WP_003090500.1 DUF5329 domain-containing protein -
  C5B40_RS21570 - 4554530..4555723 (-) 1194 WP_024946954.1 NnrS family protein -
  C5B40_RS21575 ppyR 4555710..4555967 (-) 258 WP_003090502.1 psl/pyoverdine operon transcriptional regulator PpyR -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24729.20 Da        Isoelectric Point: 5.8445

>NTDB_id=249349 C5B40_RS21540 WP_003090494.1 4550769..4551440(-) (ciaR) [Pseudomonas aeruginosa strain JB2]
MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA
RGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR
YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide


Download         Length: 672 bp        

>NTDB_id=249349 C5B40_RS21540 WP_003090494.1 4550769..4551440(-) (ciaR) [Pseudomonas aeruginosa strain JB2]
ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT
GGACTGGCTGGCCGACGGCCGCGACGCGGCGGTGCAGGGCGCCAGCGAGCCCTACGACCTGATCATCCTCGACCTCGGCC
TGCCCGGGCGCCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGCCTGGGACTCGCGACTCCGGTGCTGATCCTCACCGCG
CGCGGTTCCTGGGCCGAACGCATCGATGGCCTCAAGGCCGGTGCCGACGACTACCTGACCAAGCCGTTCCATCCGGAAGA
GTTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCTGGGCTGC
GCCTGGACGAGCAGCGCCAGTGTGTGTGCCTGAACGGCGCCGACGTCGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC
TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA
TTCCAATGTCATCGAGGTCCACGTCAACCACTTGCGGCGCAAGCTCGGCCGCGAGGTGATCGAGACCCGCCGTGGCCAGG
GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZC88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

37.727

98.655

0.372
  ciaR Streptococcus pneumoniae Rx1

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae D39

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae R6

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae TIGR4

37.273

98.655

0.368
  micA Streptococcus pneumoniae Cp1015

35.683

100

0.363
  vicR Streptococcus mutans UA159

35.526

100

0.363