Detailed information NTG0248459

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: CPS94_RS00110
• Genome accession: NZ_CP023565
• Coordinates: 16313..18472 (+)
• Length: 719 a.a.
• NCBI ID: WP_112193156.1
• Uniprot ID: A0AAD0L200
• Organism: Ligilactobacillus murinus strain CR147
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 11313..23472

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CPS94_RS00085 (CPS94_00085)	rpsI	11652..12044 (+)	393	WP_004050245.1	30S ribosomal protein S9	-
CPS94_RS00090 (CPS94_00090)	-	12235..12948 (+)	714	WP_191981800.1	helix-turn-helix domain-containing protein	-
CPS94_RS00095 (CPS94_00095)	-	12885..13796 (+)	912	WP_112193163.1	IS3 family transposase	-
CPS94_RS00100 (CPS94_00100)	-	14080..15357 (+)	1278	WP_112193161.1	GHKL domain-containing protein	-
CPS94_RS00105 (CPS94_00105)	-	15371..16153 (+)	783	WP_112193159.1	LytTR family DNA-binding domain-containing protein	-
CPS94_RS00110 (CPS94_00110)	comA	16313..18472 (+)	2160	WP_112193156.1	peptide cleavage/export ABC transporter	Regulator
CPS94_RS00115 (CPS94_00115)	-	18862..19113 (+)	252	WP_112193154.1	bacteriocin	-
CPS94_RS00120 (CPS94_00120)	-	19363..19590 (+)	228	WP_112193152.1	bacteriocin	-
CPS94_RS11770	-	19856..20074 (+)	219	WP_407936384.1	hypothetical protein	-
CPS94_RS00130 (CPS94_00130)	-	20249..20935 (-)	687	WP_056958175.1	GntR family transcriptional regulator	-
CPS94_RS00135 (CPS94_00135)	-	21058..22479 (+)	1422	WP_112193150.1	glycoside hydrolase family 1 protein	-
CPS94_RS00140 (CPS94_00140)	-	22567..23043 (+)	477	WP_112195883.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-

Sequence

Protein

• Length: 719 a.a.
• Molecular weight: 80691.57 Da
• Isoelectric Point: 8.8428

>NTDB_id=248459 CPS94_RS00110 WP_112193156.1 16313..18472(+) (comA) [Ligilactobacillus murinus strain CR147]
MSSKYKKMYISQIDESDCGVASLAMILRYYGSEVSLAYLRNLAKTNIEGTTAFGIINAAQKLGLETQAIKADMTLFDMQD
VTYPFIVHVVKEKTILHYYVVLKATSDHIIIADPDPEKGIVKLRYADFEAEWTGVTLFMKPGSKYSPIKETKSNLLSLFP
RTFKNIKLIISIVIVAMLTTIISILGSYFFQVLIDNYIPNGMEQMLDIVVMGLIVAYVCNSIFVYSRDFLLAILGQKLST
DIILEYIKHIFELPLEFFSTRKTGEIVSRFTDASKIIDALASMVVSIGLDASIVIIIGVTLFFQSIRLFVITLTALPIYI
IVIMTFAKKFEKLNKHQMESNAILSSSVIEDIQGIETIKACNSETVRFNIVSEQFFDYLNKSLSYIKSDSLQQALKIFIQ
QILNVIVLWVGAKLVIQNQLSVGQLLTFVALLSYFIDPLQNIINLQPKLQSAKVAYTRMNEVYLVKSEFRDENFNYTTQK
LLGDITLSGIKYQYGYGKNVLNNVSTTIKFGEKLAIVGMSGSGKSTLVKMLVKFFDPTSGKLEFNGYPSNSISKKSLRSY
INYVPQIPYVFSGTIEENLKLGGREGVTLKDINRACEVAMIKNDIENMPLGLNTKLDENASILSEGQKQRITIARALLSP
AEVLIFDESTSSLDTITEKKIIEQLIGMKDKTIIFVVHRLSIAKKADRILVLDSGEIVEEGSHSELLAKKGYYYKLLKA

Nucleotide

• Length: 2160 bp

>NTDB_id=248459 CPS94_RS00110 WP_112193156.1 16313..18472(+) (comA) [Ligilactobacillus murinus strain CR147]
ATGTCGAGTAAATATAAAAAGATGTATATATCACAAATTGACGAATCTGATTGTGGTGTGGCTTCATTAGCCATGATACT
GCGTTATTATGGATCAGAAGTATCTTTAGCATATCTACGAAATTTAGCTAAAACAAATATTGAAGGAACTACTGCATTTG
GAATTATAAATGCAGCACAGAAATTAGGCTTGGAAACACAGGCTATTAAAGCTGACATGACCTTGTTTGATATGCAAGAT
GTTACTTATCCATTTATTGTCCATGTAGTCAAAGAAAAAACAATATTGCATTATTATGTGGTGTTAAAAGCAACATCTGA
TCATATAATTATTGCTGATCCTGATCCAGAAAAAGGAATAGTTAAATTAAGATATGCTGATTTTGAAGCAGAGTGGACAG
GTGTAACACTTTTTATGAAACCTGGTAGTAAGTATAGCCCTATCAAAGAAACTAAGAGTAATTTGTTATCTCTTTTTCCA
AGAACGTTTAAAAATATAAAATTGATCATCAGTATTGTGATAGTTGCCATGTTAACAACAATAATAAGTATTTTGGGGTC
ATATTTTTTTCAAGTATTAATAGATAACTATATACCCAATGGCATGGAACAGATGCTAGATATTGTCGTGATGGGATTAA
TAGTGGCATATGTGTGCAATTCGATTTTTGTATATAGTAGAGATTTTTTATTAGCTATTTTGGGGCAAAAATTGTCGACT
GATATTATTTTAGAGTACATTAAACATATTTTTGAGCTACCATTGGAATTTTTTTCGACAAGAAAGACGGGCGAGATCGT
TTCAAGGTTTACAGATGCTAGTAAAATAATAGATGCTTTAGCCAGTATGGTAGTTTCCATTGGACTAGATGCTAGTATAG
TTATTATTATTGGGGTGACCTTATTTTTTCAAAGTATTAGGTTATTTGTTATAACACTGACTGCTCTTCCAATATATATC
ATTGTTATTATGACTTTTGCTAAAAAATTTGAAAAATTAAATAAGCATCAAATGGAGAGTAATGCAATACTAAGTTCGTC
AGTCATCGAAGATATACAAGGTATAGAAACGATCAAGGCATGTAATAGTGAAACCGTTCGTTTTAATATAGTAAGTGAGC
AATTCTTTGATTATTTAAATAAATCACTTAGCTATATAAAAAGCGATTCTTTACAACAAGCATTGAAAATCTTTATTCAA
CAGATCTTGAATGTGATCGTTTTGTGGGTAGGCGCTAAACTAGTTATTCAAAACCAGTTATCTGTTGGACAGTTATTGAC
TTTTGTTGCATTACTATCATATTTTATTGATCCACTACAGAATATTATAAATCTTCAGCCAAAGTTGCAAAGTGCTAAAG
TTGCATATACTCGAATGAATGAAGTTTATTTGGTCAAAAGTGAATTTAGGGATGAAAATTTTAACTATACTACTCAAAAA
TTATTAGGTGATATAACATTATCAGGGATAAAATATCAATATGGATATGGGAAAAATGTATTAAATAATGTTAGTACAAC
TATAAAATTTGGCGAAAAGTTGGCTATTGTAGGGATGAGTGGCTCTGGGAAGTCTACATTAGTCAAAATGCTAGTTAAAT
TTTTTGATCCAACTTCAGGTAAGTTAGAATTTAATGGATATCCAAGTAACAGTATAAGTAAAAAGAGTTTACGTAGTTAT
ATAAACTATGTACCACAGATCCCATACGTATTTTCTGGAACAATTGAAGAGAATCTGAAATTAGGGGGAAGAGAAGGGGT
GACTCTAAAAGACATCAATAGAGCGTGTGAAGTTGCAATGATAAAAAATGATATAGAAAATATGCCTCTAGGATTAAATA
CTAAATTAGATGAAAATGCTAGTATTTTATCAGAGGGGCAAAAGCAAAGAATTACGATCGCAAGAGCGCTATTATCACCA
GCTGAGGTCTTGATTTTTGATGAATCTACAAGCTCTTTGGATACTATTACTGAGAAAAAAATAATTGAACAGTTGATAGG
GATGAAGGATAAGACCATAATTTTTGTAGTTCATAGATTATCGATCGCAAAGAAAGCTGATAGGATCTTAGTGTTAGATA
GTGGTGAAATTGTGGAAGAAGGTAGTCACAGTGAATTACTGGCAAAAAAAGGTTATTATTATAAACTTTTAAAGGCTTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-439)

• ABC transporter (ABC_tran) (501-651)

• Peptidase C39 family (Peptidase_C39) (8-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae Rx1	53.501	99.305	0.531
comA	Streptococcus pneumoniae D39	53.501	99.305	0.531
comA	Streptococcus pneumoniae R6	53.501	99.305	0.531
comA	Streptococcus mitis NCTC 12261	53.361	99.305	0.53
comA	Streptococcus pneumoniae TIGR4	53.221	99.305	0.529
comA	Streptococcus mitis SK321	52.801	99.305	0.524
comA	Streptococcus gordonii str. Challis substr. CH1	51.681	99.305	0.513
comA/nlmT	Streptococcus mutans UA159	51.189	99.444	0.509