Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CO692_RS02830 Genome accession   NZ_CP023515
Coordinates   394477..395781 (+) Length   434 a.a.
NCBI ID   WP_096741488.1    Uniprot ID   -
Organism   Enterococcus sp. FDAARGOS_375     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 389477..400781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO692_RS02800 (CO692_02800) - 389702..390109 (+) 408 WP_317720856.1 AsnC family transcriptional regulator -
  CO692_RS02805 (CO692_02805) - 390425..390775 (-) 351 WP_096741485.1 type II toxin-antitoxin system PemK/MazF family toxin -
  CO692_RS02810 (CO692_02810) - 390769..391032 (-) 264 WP_074932272.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  CO692_RS17560 - 391319..391486 (-) 168 WP_123906404.1 hypothetical protein -
  CO692_RS17565 - 391833..391931 (-) 99 WP_123906405.1 type I toxin-antitoxin system Fst family toxin -
  CO692_RS02815 (CO692_02815) map 391968..392777 (-) 810 WP_096741486.1 type I methionyl aminopeptidase -
  CO692_RS02820 (CO692_02820) truA 392820..393557 (-) 738 WP_096741487.1 tRNA pseudouridine(38-40) synthase TruA -
  CO692_RS02825 (CO692_02825) rlmH 393624..394103 (-) 480 WP_077452817.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CO692_RS02830 (CO692_02830) htrA 394477..395781 (+) 1305 WP_096741488.1 S1C family serine protease Regulator
  CO692_RS02835 (CO692_02835) ytpR 395858..396472 (-) 615 WP_096741489.1 YtpR family tRNA-binding protein -
  CO692_RS02840 (CO692_02840) - 396747..397208 (-) 462 WP_096741490.1 universal stress protein -
  CO692_RS02845 (CO692_02845) - 397221..397541 (-) 321 WP_026008043.1 thioredoxin family protein -
  CO692_RS02850 (CO692_02850) pepA 397674..398750 (-) 1077 WP_077452910.1 glutamyl aminopeptidase -
  CO692_RS02860 (CO692_02860) - 399043..399387 (+) 345 WP_005234590.1 peptidase -
  CO692_RS02865 (CO692_02865) - 399448..400482 (-) 1035 WP_096741491.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44842.39 Da        Isoelectric Point: 4.0569

>NTDB_id=248024 CO692_RS02830 WP_096741488.1 394477..395781(+) (htrA) [Enterococcus sp. FDAARGOS_375]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTK
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSDDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDSYTDLAVLKISSEKVTTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=248024 CO692_RS02830 WP_096741488.1 394477..395781(+) (htrA) [Enterococcus sp. FDAARGOS_375]
ATGGCAAGAAAATATGTCACACCAGGCAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATTTGGCAATGGGTTCATCTTTGACTTCAACACCAGAAACTACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACACAGGTATCCAATGTAAAACTAGACGTGACTAGCGATGTCACGAAA
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGATTGGAACAGCCTCTT
TGGTCAGCAAGGTGGACAAAGTGAAGGCGATAGCCAAAGCGACGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGTAGTG
GGGTCATCTACAAAATCGATGGCGACGATGCCTATGTCGTAACCAACAACCACGTAGTTGAAGGTCAAGACGGTTTGGAA
GTTGTCTTAGCAGATGGTACGAAAGTCAAAGCTGAATTGGTTGGTACCGATTCTTACACAGACTTAGCCGTCTTAAAAAT
CTCTTCTGAAAAAGTTACAACTGCCGCAACATTTGGTGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCCATCGCGATCG
GTTCACCTCTAGGCTCTGATTACGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACGAGCCAA
AACGAATCTGGTGGTACGATTAGTATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGAAACTCAGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGTTCTGCTTCAGGCGTTAGTG
TCGAAGGAATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTC
CGCCCTGCACTAGGGATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCAGGCGTTGTGATCTACTCAGTCAACAATGCAACTCCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATCACGAAGATCGATGATACAGAAGTCAGCACCACAACTGATCTGCAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACAATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACAGCAGAAGTAAAACTTTCCGTTGATACATCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(322-419)

Peptidase family M50 (Peptidase_M50)

(18-420)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.675

91.475

0.518
  htrA Streptococcus gordonii str. Challis substr. CH1

50.835

96.544

0.491
  htrA Streptococcus mitis NCTC 12261

55.989

82.719

0.463
  htrA Streptococcus pneumoniae TIGR4

57.602

78.802

0.454
  htrA Streptococcus pneumoniae D39

57.602

78.802

0.454
  htrA Streptococcus pneumoniae Rx1

57.602

78.802

0.454
  htrA Streptococcus pneumoniae R6

57.602

78.802

0.454

Multiple sequence alignment