Detailed information NTG0247982

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: CO687_RS05760
• Genome accession: NZ_CP023511
• Coordinates: 1168467..1170707 (+)
• Length: 746 a.a.
• NCBI ID: WP_082307454.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS_371
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1163467..1175707

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO687_RS05740 (CO687_05740)	-	1163916..1166285 (-)	2370	WP_096755042.1	cation-translocating P-type ATPase	-
CO687_RS05745 (CO687_05745)	-	1166415..1167155 (+)	741	WP_041789898.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
CO687_RS05750 (CO687_05750)	-	1167194..1167721 (+)	528	WP_082307452.1	HXXEE domain-containing protein	-
CO687_RS05755 (CO687_05755)	comEA/celA/cilE	1167818..1168483 (+)	666	WP_082307453.1	helix-hairpin-helix domain-containing protein	Machinery gene
CO687_RS05760 (CO687_05760)	comEC/celB	1168467..1170707 (+)	2241	WP_082307454.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
CO687_RS05765 (CO687_05765)	holA	1170798..1171835 (+)	1038	WP_096755043.1	DNA polymerase III subunit delta	-
CO687_RS05770 (CO687_05770)	-	1171908..1172513 (+)	606	WP_045773124.1	superoxide dismutase	-
CO687_RS05775 (CO687_05775)	-	1172625..1173698 (+)	1074	WP_096755044.1	serine hydrolase	-
CO687_RS05780 (CO687_05780)	-	1173904..1174692 (+)	789	WP_096755045.1	YhfC family glutamic-type intramembrane protease	-
CO687_RS05785 (CO687_05785)	-	1174670..1174951 (+)	282	WP_012130660.1	autorepressor SdpR family transcription factor	-
CO687_RS05790 (CO687_05790)	-	1174938..1175435 (+)	498	WP_082307456.1	DUF1648 domain-containing protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85608.52 Da
• Isoelectric Point: 9.8830

>NTDB_id=247982 CO687_RS05760 WP_082307454.1 1168467..1170707(+) (comEC/celB) [Streptococcus gordonii strain FDAARGOS_371]
MSQWIKKLPLSPIYLCFLLVWLYFAIYSGEKLAYMGVFLLIARLIWHYPRKKWLPTVAILIAFFIFFYARRELAERTFQS
QPAPARQVLVLPDTIKVNGDSLSFRGRIGGRLYQLYYKLASPREKESFQKLADLVTLEIEAEFNLAEERRNFSGFDYQAY
LKSQGIYRTVKVSRIMSSRSSQSANPFDWLSVWRRKALVFIKSTFPSPMSHYMTGLLFGDLDIDFAEMNDLYSSLGIIHL
FALSGMQVGFFMDVFRKILLRIGLRMETVDWLQFPLSFVYAGLTGFSVSVVRSLVQKLLSQFGVRRLDNFAMTVMVLMFL
MPSFLLTTGGVLSCAYAFIITMLDFEDSSGFRKAVLESLSISLGILPILIYYFAEFQPWSILLTFLFSIVFDTFMLPLLS
LIFLISPLFAFTQVNIFFQWLEMVIRWVASLSTRPIILGQPNLPLLIILLLVLALLYDFRKQKKIRVGLSLLAILLFFLS
KHPLQNEITVVDIGQGDSIFLRDVRGRTIVIDTGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDRLDKLVLTHTDT
DHMGDMLELAKHFSIREIYVSKGSMTQADFVDKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLTQGDGGNDDSIVLYGEF
FRTKFLFTGDLEALGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHKETLDRFEKIR
TKIFRTDEQGAIRFKGWNSWQIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=247982 CO687_RS05760 WP_082307454.1 1168467..1170707(+) (comEC/celB) [Streptococcus gordonii strain FDAARGOS_371]
ATGTCACAGTGGATTAAAAAACTTCCCCTTTCACCAATCTACTTGTGCTTTCTTTTGGTTTGGCTCTACTTCGCTATTTA
TAGTGGGGAAAAGCTCGCTTATATGGGAGTTTTTCTGCTTATAGCCCGACTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTGTAGCTATCCTAATTGCTTTTTTTATCTTTTTTTATGCTAGACGTGAGTTGGCGGAGCGAACCTTTCAGTCT
CAACCAGCTCCAGCAAGACAAGTCTTAGTTTTACCAGATACAATTAAAGTAAATGGAGATTCCCTGTCATTCCGTGGTAG
AATAGGTGGCAGACTCTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAGAATCATTTCAAAAACTAGCGGACT
TGGTCACTTTAGAGATTGAAGCAGAGTTTAATCTAGCAGAAGAACGGCGCAATTTCTCTGGCTTTGACTATCAGGCTTAT
TTAAAAAGTCAGGGAATCTATCGGACGGTTAAGGTCAGTAGGATTATGTCTAGTCGTTCTAGTCAGTCTGCTAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCCTTGGTTTTCATTAAGTCTACTTTTCCAAGCCCGATGAGTCACTACATGA
CAGGACTCTTGTTTGGTGATTTAGATATTGATTTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAAGTTGGTTTTTTTATGGATGTCTTTCGGAAAATTCTTCTACGCATAGGCTTAAGGATGGA
AACAGTAGATTGGTTGCAATTCCCTTTGTCCTTCGTGTATGCTGGTTTGACCGGATTTTCTGTGTCAGTAGTTAGAAGTT
TAGTGCAAAAGTTGTTGTCTCAATTTGGAGTGAGGCGCTTGGATAATTTTGCGATGACCGTGATGGTTTTGATGTTTCTT
ATGCCAAGTTTTCTCCTGACAACAGGTGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACTATGTTGGATTTTGAGGA
TTCTAGTGGTTTTCGTAAAGCCGTGCTAGAGAGTTTAAGTATCTCGTTAGGCATTTTACCGATTCTTATCTACTATTTTG
CAGAATTCCAACCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTCTTTGATACATTTATGTTGCCTCTCTTGAGT
CTAATTTTTCTCATTTCGCCTTTGTTTGCCTTCACTCAAGTTAACATCTTCTTCCAATGGCTGGAAATGGTGATTCGTTG
GGTAGCTAGTTTGTCAACAAGGCCGATAATTTTAGGACAGCCAAATCTGCCTTTGCTTATTATTCTCCTGCTGGTCTTAG
CCTTGCTCTATGACTTTAGAAAACAAAAAAAGATTAGGGTTGGCCTGAGTCTCTTAGCAATCTTACTATTTTTCCTAAGT
AAACATCCTTTACAAAATGAAATCACAGTGGTAGATATTGGGCAGGGAGACAGTATATTTCTGAGAGATGTCAGAGGTAG
GACTATCGTGATTGATACAGGAGGACGGGTGGAGATTGGAAAAAAAGAAGCTTGGCAAGAGCGCGTGAGAAAAAGTAATG
CGGAAACGACCTTGATCCCTTATCTAAAAAGCCGAGGAGTGGATCGATTGGATAAATTGGTCTTGACTCATACCGATACA
GACCATATGGGAGATATGTTGGAGTTAGCTAAGCACTTTTCTATCCGAGAAATTTATGTTTCCAAAGGAAGTATGACTCA
AGCTGATTTTGTAGACAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTGGTCGAGGTGGGAGATCGGCTTCCTATTTTTG
ATTCGGCTCTTGAAGTGCTCTACCCGCTTACTCAAGGAGATGGAGGTAATGATGATTCAATTGTCTTGTATGGTGAATTT
TTCCGAACCAAGTTTCTTTTCACAGGAGATTTAGAAGCTCTAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAACCGTTACCAGCATCCGCATAAGGAAACTTTAGATAGATTCGAAAAAATCCGG
ACTAAGATTTTTCGGACAGATGAGCAGGGAGCTATTCGATTTAAAGGCTGGAATTCTTGGCAGATAGAAACGGTTCGCTA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

• Competence protein (Competence) (216-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	57.314	100	0.578
comEC/celB	Streptococcus pneumoniae TIGR4	56.359	100	0.564
comEC/celB	Streptococcus mitis NCTC 12261	56.434	100	0.564
comEC/celB	Streptococcus pneumoniae Rx1	55.689	100	0.558
comEC/celB	Streptococcus pneumoniae D39	55.689	100	0.558
comEC/celB	Streptococcus pneumoniae R6	55.689	100	0.558
comEC	Lactococcus lactis subsp. cremoris KW2	49.597	99.732	0.495