Detailed information NTG0247932

Bioinformatically predicted

Overview

• Name: stkP
• Type: Regulator
• Locus tag: CO687_RS00190
• Genome accession: NZ_CP023511
• Coordinates: 27076..28929 (-)
• Length: 617 a.a.
• NCBI ID: WP_096754704.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS_371
• Function: require for competence development; phosphorylate ComE (predicted from homology) Competence regulation

Genomic Context

Location: 22076..33929

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO687_RS00150 (CO687_00150)	-	22087..22515 (-)	429	Protein_16	sigma-70 family RNA polymerase sigma factor	-
CO687_RS00155 (CO687_00155)	-	22657..23070 (-)	414	Protein_17	DNA/RNA helicase	-
CO687_RS00160 (CO687_00160)	-	23082..23189 (-)	108	Protein_18	HPF/RaiA family ribosome-associated protein	-
CO687_RS00165 (CO687_00165)	-	23326..23664 (+)	339	Protein_19	DUF1949 domain-containing protein	-
CO687_RS00170 (CO687_00170)	-	23762..24055 (+)	294	Protein_20	pyridoxal-phosphate dependent enzyme	-
CO687_RS00175 (CO687_00175)	-	24993..25205 (-)	213	Protein_21	response regulator transcription factor	-
CO687_RS00180 (CO687_00180)	-	25207..26208 (-)	1002	WP_061583693.1	sensor histidine kinase	-
CO687_RS00185 (CO687_00185)	liaF	26205..26903 (-)	699	WP_045506061.1	cell wall-active antibiotics response protein LiaF	-
CO687_RS00190 (CO687_00190)	stkP	27076..28929 (-)	1854	WP_096754704.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
CO687_RS00195 (CO687_00195)	-	28926..29666 (-)	741	WP_045772999.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
CO687_RS00200 (CO687_00200)	rsmB	29687..31000 (-)	1314	WP_096754705.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
CO687_RS00205 (CO687_00205)	fmt	30990..31925 (-)	936	WP_061596060.1	methionyl-tRNA formyltransferase	-

Sequence

Protein

• Length: 617 a.a.
• Molecular weight: 67149.20 Da
• Isoelectric Point: 6.5896

>NTDB_id=247932 CO687_RS00190 WP_096754704.1 27076..28929(-) (stkP) [Streptococcus gordonii strain FDAARGOS_371]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRVTDIG
EEDGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHARGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENANVP
QSLENVIIKATAKKLTDRYQSVSDMYVDLSSCLSPERRNEKKLMFDDAVKADTKTLPKIPQVTPPVAFRVNNDPATDVEQ
KVPQVAPPTKPKKKHHLRARYKVLLAAVFLVIAAFLALLYLTPSNKQVPDVTGKTVAEAREAIEKVNLKVGEEIEENSDE
VASGMIIRTDPVAGTQRKEGSTVNLVVSKGAKTLIMEDYTGQTTAQAVERLTDVLKVPKNNIKVEEVETNDAEEGTIFEQ
TPAAGATYDLTSNTKIVLKVAKAVSTIEMPNFGSLQYTYANARNYLISLGIPSSNIERVVDRSVVSSQSDLVTSQSPATG
PVNPKKVKVTLYVTEATTQSSSSSSSSNSNSSSSSKNTSSSSSSEDETSASSSTHGD

Nucleotide

• Length: 1854 bp

>NTDB_id=247932 CO687_RS00190 WP_096754704.1 27076..28929(-) (stkP) [Streptococcus gordonii strain FDAARGOS_371]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCAAACAAATTGGCCGAGGCGGGATGGCAGATGTCTA
TCTTGCCAAGGATTTGATTTTAGATGGTGAAGAAGTGGCGGTTAAGGTTCTTAGAACCAATTACCAGACGGATCCTATCG
CTGTTGCACGTTTCCAACGAGAAGCGCGTGCCATGGCGGATTTGGACCATCCACATATCGTTCGTGTCACCGATATTGGC
GAAGAAGACGGCCAGCAATATTTGGCTATGGAATATGTAGCTGGCTTGGATCTCAAACGATACATTAAAGAGCACGCTCC
TTTGTCGAACGAGGAAGCCGTTCGAATTATGGGACAAATTCTTTTAGCTATGCGCTTGGCACATGCTCGTGGGATTGTTC
ACCGAGATTTGAAACCGCAAAACGTTCTCCTGACTCCAGATGGAAATGCTAAGGTAACGGACTTTGGGATTGCGGTTGCC
TTTGCAGAAACAAGTTTGACCCAAACAAATTCCATGCTTGGTAGTGTCCATTATTTGTCTCCTGAGCAGGCGCGTGGTTC
GAAAGCAACTTTCCAAAGCGATATCTATGCGATGGGGATCATCTTTTATGAGATGCTGACTGGTCATATTCCTTATGATG
GGGATAGTGCAGTGACAATCGCTCTGCAACATTTCCAAAAACCATTGCCGTCCATTATTGCTGAAAACGCCAATGTTCCG
CAGTCTTTGGAAAATGTTATTATTAAGGCTACTGCTAAAAAGCTGACAGATCGATATCAGAGTGTTTCGGATATGTATGT
AGATCTGTCTAGCTGCCTGTCACCTGAACGACGGAATGAAAAGAAACTGATGTTTGATGACGCGGTAAAAGCGGATACTA
AAACACTTCCGAAGATTCCACAAGTCACACCTCCTGTAGCTTTTAGAGTAAATAATGATCCAGCTACAGATGTTGAACAG
AAAGTCCCTCAAGTTGCACCGCCAACAAAACCTAAGAAAAAGCATCATTTGAGAGCGAGATACAAGGTTTTGTTAGCTGC
AGTATTTCTGGTCATTGCTGCTTTTCTAGCTTTGCTCTATCTAACACCATCTAATAAGCAGGTTCCAGATGTTACTGGCA
AGACAGTTGCTGAAGCTAGAGAAGCGATTGAAAAAGTCAATTTAAAAGTTGGCGAAGAAATAGAAGAGAATAGTGATGAA
GTAGCTTCTGGAATGATTATTCGAACAGATCCAGTGGCAGGGACTCAGAGAAAGGAAGGCAGTACGGTTAATTTAGTTGT
TTCTAAGGGAGCTAAAACGCTGATCATGGAAGACTATACTGGTCAAACTACTGCCCAAGCCGTTGAAAGGCTCACGGATG
TTCTAAAAGTTCCAAAAAACAATATTAAAGTTGAAGAAGTTGAAACAAACGATGCAGAAGAAGGAACAATTTTTGAACAG
ACACCAGCTGCGGGAGCTACCTATGATCTCACTTCAAATACGAAGATTGTTTTAAAAGTAGCCAAAGCAGTATCAACGAT
TGAAATGCCAAACTTTGGTAGCCTTCAATATACTTATGCAAACGCTCGAAATTATCTGATTTCTCTAGGAATTCCATCTA
GCAACATTGAAAGAGTCGTGGATCGTTCAGTTGTGTCGAGTCAATCTGATTTGGTGACATCACAATCTCCAGCAACTGGA
CCAGTTAATCCTAAGAAGGTAAAAGTAACCTTATATGTAACTGAAGCAACTACTCAAAGTTCAAGCTCTAGCTCAAGTTC
GAATTCTAACTCCTCATCAAGTAGCAAGAATACGTCATCGTCAAGTTCTTCAGAGGATGAAACTTCAGCATCAAGTTCGA
CACATGGTGATTAA

Domains

Predicted by InterproScan.

• PASTA domain (PASTA) (435-502)

• PASTA domain (PASTA) (367-429)

• PASTA domain (PASTA) (508-574)

• Protein kinase domain (Pkinase) (12-243)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
stkP	Streptococcus pneumoniae TIGR4	70.543	83.63	0.59
stkP	Streptococcus pneumoniae D39	70.349	83.63	0.588
stkP	Streptococcus pneumoniae R6	70.349	83.63	0.588
stkP	Streptococcus pneumoniae Rx1	70.155	83.63	0.587
pknB	Streptococcus mutans UA159	57.343	92.707	0.532
stkP/pknB	Streptococcus salivarius strain HSISS4	57.847	88.817	0.514