Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   CO686_RS07190 Genome accession   NZ_CP023507
Coordinates   1453243..1455156 (-) Length   637 a.a.
NCBI ID   WP_096753667.1    Uniprot ID   A0AAW7W8Y9
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1448243..1460156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS07160 (CO686_07160) - 1448258..1449223 (+) 966 WP_049501092.1 LacI family DNA-binding transcriptional regulator -
  CO686_RS07170 (CO686_07170) - 1449375..1450649 (-) 1275 WP_049489528.1 hydroxymethylglutaryl-CoA reductase, degradative -
  CO686_RS07175 (CO686_07175) - 1450649..1451821 (-) 1173 WP_096753809.1 hydroxymethylglutaryl-CoA synthase -
  CO686_RS07180 (CO686_07180) - 1451940..1452395 (-) 456 WP_000176908.1 threonine/serine exporter family protein -
  CO686_RS07185 (CO686_07185) - 1452397..1453155 (-) 759 WP_000344543.1 threonine/serine exporter family protein -
  CO686_RS07190 (CO686_07190) stkP 1453243..1455156 (-) 1914 WP_096753667.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  CO686_RS07195 (CO686_07195) - 1455153..1455893 (-) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  CO686_RS07200 (CO686_07200) rsmB 1455909..1457222 (-) 1314 WP_172844177.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CO686_RS07205 (CO686_07205) fmt 1457215..1458150 (-) 936 WP_096753669.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69409.73 Da        Isoelectric Point: 9.2842

>NTDB_id=247869 CO686_RS07190 WP_096753667.1 1453243..1455156(-) (stkP) [Streptococcus oralis strain FDAARGOS_367]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKASAQEERPQPK
KPTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLVWILSRTPATIAIPNVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKEKKVPENLIKMEEEESSESEPGTV
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYIGSSLEFTKNNLTQIVGVKEANIEVVEVSNAPEGTAEGTVVSQTP
RAGELVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSPTSPTQGNQQGNQQGNQQGNNPPTNQPNGERNHESSRD

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=247869 CO686_RS07190 WP_096753667.1 1453243..1455156(-) (stkP) [Streptococcus oralis strain FDAARGOS_367]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAACGTGAAGCGAGAGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGCCTTGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAATGAAGAAGCAGTTCGGATTATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCTGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCTGTAGCC
TTTGCGGAGACTAGTCTGACCCAGACCAACTCAATGTTAGGCTCTGTTCATTATTTGTCACCTGAGCAAGCACGTGGTTC
TAAAGCGACTTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAGATGCTGACGGGACATATCCCTTACGATG
GGGATAGCGCGGTTACGATTGCCCTCCAGCATTTCCAGAAACCACTTCCGTCCGTCATAGCTGAAAATCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCTAAGAAGCTGTCAGATCGTTATCAGTCTGTTTCGGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGCAATGAACCGAAGCTGGTCTTTGATGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCTTCGGCGCAGGAAGAACGCCCTCAGCCAAAG
AAACCAACTCAACCAGTGGCAGAGCCGGCTCCAGCGCCAAAGCCAGCCAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCAGCCTCTTTGGTCTGGATTTTGTCAAGAACACCAGCAACGATTGCTATTCCTA
ACGTAGCTGGACAAACCGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCCAAGTTTGAAGCCGGTGAAGAAAAGTCAGAA
GCCAGCGATACAGTAGCAGAAGGACGTGTTATTCGAACGGATCCAGAAGCTGGTAGTGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGTAAGCAATCCTTCCAATTGAGCAATTATGTCGGACGCAAGTATACGGATGTCGTAGCTG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGCGAACCTGGCACCGTC
CTCAGACAGACCCCTGCTTCGGGTTCGACCTATGATCTCTCAAAAGCCACTACGATTACCTTAACAGTGGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATCGGTTCAAGTCTCGAGTTTACAAAGAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTAGAAGTATCGAATGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTAAGTCAAACGCCA
AGAGCAGGAGAACTGGTTGATCTTGCAAGTACGCGTATCAAACTTTCCATCTACAAACCAAAAACACCACCATCAACTTC
ATCCTCTAATCCTGCCCAACGTGGGAACCAGGGTTCTCCTACAAGTCCAACCCAGGGGAACCAGCAAGGAAATCAACAAG
GTAACCAACAAGGCAACAATCCTCCAACGAATCAACCAAACGGTGAAAGAAACCACGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.669

91.994

0.724
  stkP Streptococcus pneumoniae D39

78.328

91.994

0.721
  stkP Streptococcus pneumoniae R6

78.328

91.994

0.721
  stkP Streptococcus pneumoniae Rx1

78.157

91.994

0.719
  pknB Streptococcus mutans UA159

56.499

90.581

0.512
  stkP/pknB Streptococcus salivarius strain HSISS4

53.12

93.093

0.495

Multiple sequence alignment