Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CO686_RS03130 Genome accession   NZ_CP023507
Coordinates   633493..634233 (+) Length   246 a.a.
NCBI ID   WP_000782705.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 628493..639233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS03120 (CO686_03120) - 629317..631845 (+) 2529 WP_000792509.1 MBL fold metallo-hydrolase -
  CO686_RS03125 (CO686_03125) - 631892..633370 (-) 1479 WP_049490167.1 oligosaccharide flippase family protein -
  CO686_RS03130 (CO686_03130) mecA 633493..634233 (+) 741 WP_000782705.1 adaptor protein MecA Regulator
  CO686_RS03135 (CO686_03135) - 634381..635667 (+) 1287 WP_000216365.1 homoserine dehydrogenase -
  CO686_RS03140 (CO686_03140) thrB 635669..636538 (+) 870 WP_045617364.1 homoserine kinase -
  CO686_RS03150 (CO686_03150) msrB 636796..637734 (+) 939 WP_096753484.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28513.30 Da        Isoelectric Point: 4.1097

>NTDB_id=247851 CO686_RS03130 WP_000782705.1 633493..634233(+) (mecA) [Streptococcus oralis strain FDAARGOS_367]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETESKKEPYIYYILRFA
SLADLVSFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=247851 CO686_RS03130 WP_000782705.1 633493..634233(+) (mecA) [Streptococcus oralis strain FDAARGOS_367]
ATGAAGATGAAACAAATCAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCGATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTCGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATTTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAAAAGAGTATTGCAGATAAAACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAGTAAGAAAGAACCTTATATATACTATATCCTGCGCTTTGCA
AGCCTTGCTGACTTAGTTTCTTTTGCAAAGACGGTTAACTACCAGATGGAAACCTCTGAACTCTATAAGATGAATGGACA
CTATTATTTGACAATCTTAGTCGATGTAGAAAATCATCCAAGTCCATATCCAGCCTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGATATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTCGGT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.574

99.187

0.898
  mecA Streptococcus pneumoniae D39

90.574

99.187

0.898
  mecA Streptococcus pneumoniae R6

90.574

99.187

0.898
  mecA Streptococcus pneumoniae TIGR4

90.164

99.187

0.894
  mecA Streptococcus thermophilus LMD-9

47.619

100

0.488
  mecA Streptococcus thermophilus LMG 18311

47.222

100

0.484
  mecA Streptococcus mutans UA159

48.361

99.187

0.48

Multiple sequence alignment