Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CO204_RS09325 Genome accession   NZ_CP023477
Coordinates   1845691..1846413 (-) Length   240 a.a.
NCBI ID   WP_019313045.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1840691..1851413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS09300 (CO204_09255) sufU 1840726..1841160 (-) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -
  CO204_RS09305 (CO204_09260) - 1841147..1842376 (-) 1230 WP_002271229.1 cysteine desulfurase -
  CO204_RS09310 (CO204_09265) sufD 1842381..1843643 (-) 1263 WP_002262746.1 Fe-S cluster assembly protein SufD -
  CO204_RS09315 (CO204_09270) sufC 1843681..1844451 (-) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  CO204_RS09320 (CO204_09275) rgpG 1844525..1845685 (-) 1161 WP_019313046.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  CO204_RS09325 (CO204_09280) mecA 1845691..1846413 (-) 723 WP_019313045.1 adaptor protein MecA Regulator
  CO204_RS09330 (CO204_09285) - 1846503..1847348 (-) 846 WP_002262750.1 undecaprenyl-diphosphate phosphatase -
  CO204_RS09335 (CO204_09290) - 1847406..1849307 (-) 1902 WP_019313044.1 DUF2207 domain-containing protein -
  CO204_RS09340 (CO204_09295) - 1849459..1851012 (+) 1554 WP_002266996.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28058.65 Da        Isoelectric Point: 4.2340

>NTDB_id=247448 CO204_RS09325 WP_019313045.1 1845691..1846413(-) (mecA) [Streptococcus mutans strain LAR01]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEIEKREEEKTQQEKSETKEKRDYVHFVLDFPNIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=247448 CO204_RS09325 WP_019313045.1 1845691..1846413(-) (mecA) [Streptococcus mutans strain LAR01]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATACTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGGACAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCTCCGGAGGATTTCTTTAATACCTT
GGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAAGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTAATATTCAGCAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCGAAGATAAACCCGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

99.167

100

0.992
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.571

100

0.496
  mecA Streptococcus pneumoniae D39

48.571

100

0.496
  mecA Streptococcus pneumoniae R6

48.571

100

0.496
  mecA Streptococcus pneumoniae TIGR4

48.571

100

0.496

Multiple sequence alignment