Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AOY69_RS13485 Genome accession   NZ_CP028758
Coordinates   2862216..2864048 (-) Length   610 a.a.
NCBI ID   WP_028132062.1    Uniprot ID   -
Organism   Escherichia coli strain A16     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2857216..2869048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY69_RS13440 (AOY69_14270) yecR 2857563..2857886 (+) 324 WP_087900996.1 YecR-like lipofamily protein -
  AOY69_RS13445 (AOY69_14275) ftnA 2858057..2858554 (+) 498 WP_087900997.1 non-heme ferritin -
  AOY69_RS13450 (AOY69_14280) yecH 2858592..2858831 (-) 240 WP_000377224.1 YecH family metal-binding protein -
  AOY69_RS13455 (AOY69_14285) tyrP 2859023..2860234 (+) 1212 WP_000797566.1 tyrosine transporter TyrP -
  AOY69_RS13460 (AOY69_14290) yecA 2860296..2860961 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  AOY69_RS13480 (AOY69_14310) pgsA 2861611..2862159 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AOY69_RS13485 (AOY69_14315) uvrC 2862216..2864048 (-) 1833 WP_028132062.1 excinuclease ABC subunit UvrC Machinery gene
  AOY69_RS13490 (AOY69_14320) letA 2864045..2864701 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AOY69_RS23350 - 2864843..2864914 (+) 72 Protein_2632 transcriptional regulator -
  AOY69_RS13495 yecU 2864997..2865173 (+) 177 WP_000590347.1 protein YecU -
  AOY69_RS13500 (AOY69_14325) yecF 2865160..2865384 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  AOY69_RS13505 (AOY69_14330) sdiA 2865452..2866174 (-) 723 WP_024231281.1 transcriptional regulator SdiA -
  AOY69_RS13510 (AOY69_14335) tcyN 2866404..2867156 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AOY69_RS13515 (AOY69_14340) tcyL 2867153..2867821 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  AOY69_RS13520 (AOY69_14345) dcyD 2867836..2868822 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68197.04 Da        Isoelectric Point: 9.3687

>NTDB_id=247358 AOY69_RS13485 WP_028132062.1 2862216..2864048(-) (uvrC) [Escherichia coli strain A16]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASHNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=247358 AOY69_RS13485 WP_028132062.1 2862216..2864048(-) (uvrC) [Escherichia coli strain A16]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCTGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAATGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCATGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTTAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTGATTAGCCGTA
TGGAAACTGCCAGTCACAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTTGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTTGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGACAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGACAGTAAGATCCCGGATGTGATACTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGCCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae R6

37.397

99.508

0.372
  uvrC Streptococcus pneumoniae D39

37.397

99.508

0.372

Multiple sequence alignment